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Daniel B Dadon, 37Boston, MA

Known as:
Daniel Dodan
Related to:
Charity L Ostrowski 48

Daniel Dadon Phones & Addresses

Boston, MA   

Cambridge, MA   

Westlake Village, CA   

San Diego, CA   

Agoura Hills, CA   

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Resumes

Daniel Dadon Photo 13

Director Of Scientific Strategy And Business Development

Location:
Cambridge, MA
Industry:
Biotechnology
Work:
Evelo Biosciences Jun 2016 - Sep 2016
Scientific Strategy and Corporate Development Fellow Massachusetts Institute of Technology (Mit) Jun 2011 - May 2016
Nsf Graduate Research Fellow Elektrofi Jun 2011 - May 2016
Director of Scientific Strategy and Business Development University of California, San Diego Dec 2008 - Aug 2010
Assistant Iii Biogen Sep 2008 - Jan 2009
Associate Scientist I
Education:
Massachusetts Institute of Technology 2010 - 2015
Doctorates, Doctor of Philosophy, Biology Uc San Diego 2004 - 2009
Bachelors, Bachelor of Science, Molecular Biology Agoura High School 2000 - 2004
Skills:
Molecular Biology, Biochemistry, Computational Biology, Genomics, Chromatography, Drug Design, Biotechnology, Protein Purification, Research, Data Analysis, Genome Editing, Leadership, Project Management, Business Development, Public Speaking, Market Research, Microsoft Excel, Strategic Planning, Powerpoint, Business Strategy
Languages:
Spanish
Daniel Dadon Photo 14

Graduate Research Fellow

Location:
Boston, MA
Work:
Massachusetts Institute of Technology (Mit)
Graduate Research Fellow

Publications & IP owners

Us Patents

Peptide Particles And Methods Of Formation

US Patent:
2023009, Mar 30, 2023
Filed:
Feb 5, 2021
Appl. No.:
17/759594
Inventors:
- Boston MA, US
Chase Spenser Coffman - Newton MA, US
Daniel Benjamin Dadon - East Boston MA, US
Chaitanya Sudrik - Stoneham MA, US
International Classification:
A61K 9/16
A61K 38/03
A61K 41/17
Abstract:
The present disclosure relates to compositions and methods that enable the formation of pharmaceutically relevant particles that can be used for therapy. In particular, the methods disclosed herein allow the controlled formation of circular particles comprising biologically active peptides.

Formation Of Particles Including Agents

US Patent:
2021032, Oct 21, 2021
Filed:
Jun 30, 2021
Appl. No.:
17/364770
Inventors:
- Boston MA, US
Paul Brown - Boston MA, US
Daniel Benjamin Dadon - East Boston MA, US
Lisa Liu - Somerville MA, US
Cory Robinson - Cambridge MA, US
International Classification:
A61K 9/14
B01J 2/06
Abstract:
The invention provides methods for the preparation of particles including one or more agents, e.g., therapeutic or diagnostic agents. The particles can be formed by creating droplets of a first liquid, e.g., including an agent, and removing the first liquid, e.g., through its dispersal in a second liquid and/or evaporation, to solidify the droplets. Advantageously, the process of forming the particles does not significantly alter the structure or activity of the agents and may enhance the stability of the agents. For example, the particles may be stored for long periods of time without significant loss of activity, and in some embodiments, without the need for refrigeration. These particles may be used to generate stabilized pharmaceutical compositions for storage or other logistical purposes, pharmaceutical suspensions, pharmaceutical powder formulations (e.g., inhalable powders, injectable powders), creams or other topical pastes, nutraceuticals, or cosmetics.

Particle Formation And Morphology

US Patent:
2021031, Oct 14, 2021
Filed:
Jun 18, 2021
Appl. No.:
17/351937
Inventors:
- Boston MA, US
Chase Spenser Coffman - Newton MA, US
Daniel Benjamin Dadon - East Boston MA, US
James Ivey - Somerville MA, US
Lisa Liu - Somerville MA, US
Chaitanya Sudrik - Stoneham MA, US
International Classification:
A61K 9/51
C07K 16/00
Abstract:
The present disclosure relates to compositions and methods that enable the formation of pharmaceutically relevant particles that can be used for therapy. In particular, the methods disclosed herein allow the controlled formation of circular particles having low internal void spaces comprising bioactive therapeutic agents.

Compositions And Methods For The Delivery Of Therapeutic Biologics For Treatment Of Disease

US Patent:
2021030, Oct 7, 2021
Filed:
Jun 18, 2021
Appl. No.:
17/351963
Inventors:
- Boston MA, US
Tyler L. Carter - Newburyport MA, US
Chase Spenser Coffman - Newton MA, US
Daniel Benjamin Dadon - East Boston MA, US
Lisa Liu - Somerville MA, US
Sadiqua Shadbar - Allston MA, US
Chaitanya Sudrik - Stoneham MA, US
Yi Tang - Medford MA, US
Shankul Vartak - Cambridge MA, US
International Classification:
C07K 16/00
A61K 45/06
Abstract:
The present disclosure provides compositions and methods for treating a disease or condition in a subject in need thereof, comprising administering to the subject a pharmaceutically effective amount of a composition comprising a plurality of particles comprising at least one therapeutic biologic suspended in a pharmaceutically acceptable liquid carrier.

Particles Comprising A Therapeutic Or Diagnostic Agent And Suspensions And Methods Of Use Thereof

US Patent:
2021022, Jul 22, 2021
Filed:
May 24, 2019
Appl. No.:
17/058339
Inventors:
- Boston MA, US
Lyndon CHARLES, Jr. - Medford MA, US
Paul BROWN - Boston MA, US
Daniel Benjamin DADON - East Boston MA, US
Lisa LIU - Somerville MA, US
Sadiqua SHADBAR - Allston MA, US
Chaitanya SUDRIK - Cambridge MA, US
International Classification:
A61K 9/51
A61K 47/02
A61K 47/26
A61K 47/14
A61K 47/18
A61K 31/167
A61K 45/06
Abstract:
The invention provides particles, compositions including the particles, and methods of making the particles using electrospray. In certain embodiments, the particles allow for high concentrations of a therapeutic or diagnostic agent to be delivered at low viscosity. Particles may also exhibit beneficial properties with respect to stability.

Formation Of Particles Including Agents

US Patent:
2020025, Aug 13, 2020
Filed:
Jul 25, 2018
Appl. No.:
16/633097
Inventors:
- Boston MA, US
Paul Brown - Boston MA, US
Daniel Benjamin Dadon - Cambridge MA, US
Lisa Liu - Cambridge MA, US
Cory Robinson - Cambridge MA, US
International Classification:
A61K 9/14
B01J 2/06
Abstract:
The invention provides methods for the preparation of particles including one or more agents, e.g., therapeutic or diagnostic agents. The particles can be formed by creating droplets of a first liquid, e.g., including an agent, and removing the first liquid, e.g., through its dispersal in a second liquid and/or evaporation, to solidify the droplets. Advantageously, the process of forming the particles does not significantly alter the structure or activity of the agents and may enhance the stability of the agents. For example, the particles may be stored for long periods of time without significant loss of activity, and in some embodiments, without the need for refrigeration. These particles may be used to generate stabilized pharmaceutical compositions for storage or other logistical purposes, pharmaceutical suspensions, pharmaceutical powder formulations (e.g., inhalable powders, injectable powders), creams or other topical pastes, nutraceuticals, or cosmetics.

Particles Comprising A Therapeutic Or Diagnostic Agent And Suspensions And Methods Of Use Thereof

US Patent:
2019037, Dec 12, 2019
Filed:
Nov 22, 2017
Appl. No.:
16/463238
Inventors:
- Boston MA, US
Lyndon CHARLES - Medford MA, US
Paul BROWN - Boston MA, US
Daniel Benjamin DADON - Cambridge MA, US
Lisa LIU - Somerville MA, US
Cory ROBINSON - Cambridge MA, US
International Classification:
A61K 9/16
A61K 39/395
B05B 5/025
Abstract:
The invention provides particles, compositions including the particles, and methods of making the particles using electrospray. In certain embodiments, the particles allow for high concentrations of a therapeutic or diagnostic agent to be delivered at low viscosity. Particles may also exhibit beneficial properties with respect to stability.

Chromosome Neighborhood Structures And Methods Relating Thereto

US Patent:
2019000, Jan 3, 2019
Filed:
Jul 14, 2016
Appl. No.:
15/744685
Inventors:
- Cambridge MA, US
Richard A. Young - Boston MA, US
Diego R. Borges-Rivera - Belmont MA, US
Abraham S. Weintraub - Somerville MA, US
Xiong Ji - Cambridge MA, US
Daniel B. Dadon - Cambridge MA, US
Zi Peng Fan - Waltham MA, US
Tong Ihn Lee - Somerville MA, US
International Classification:
G06F 19/20
C12Q 1/6886
Abstract:
Work described herein reveals 3D regulatory landscapes of hESCs representative of early human development. This work also demonstrates that cohesin-associated CTCF loops, and the cohesin-associate enhancer-promoter loops within them, dominate the organization of TADs. The CTCF-CTCF loops form a chromosomal scaffold of insulated neighborhoods that are largely preserved in vertebrates, and enhancer-promoter interactions occur within these neighborhoods. Genes are regulated in the context of conserved insulated neighborhood structures. Loss of neighborhood structures occurs frequently in cancer cells, and proto-oncogenes can be activated by genetic alterations that disrupt specific 3D chromosome structures.

Possible Relatives

Linda Dadon  Meir Dadon  Daniel G Last  Daniel J Johnson  Daniel W Stamps  Daniel C Stan  Daniel Stancil  Daniel S Standage  Daniel W Standifer  Daniel J Standish 

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