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Deborah F Boles, 66Wilmington, NC

Known as:
Deborah Faye White Deborah F White Debrah F Boles Frank Boles Debora H White Deb White Beatrice Elliott
Related to:
Geraldine Boles

Deborah Boles Phones & Addresses

Wilmington, NC   

Garner, NC   

Raleigh, NC   

110 Ashley Rd, Apex, NC 27502   

Cary, NC   

New Rochelle, NY   

Wake Forest, NC   

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Mentions for Deborah F Boles

Career records & work history

Medicine Doctors

Deborah Boles

Specialties:
Family Medicine
Work:
Valley Family Practice
3524 Heathrow Way, Medford, OR 97504
541-6463505 (phone) 541-6463553 (fax)
Site
Languages:
English, Spanish
Description:
Ms. Boles works in Medford, OR and specializes in Family Medicine. Ms. Boles is affiliated with Asante Rogue Regional Medical Center and Providence Medford Medical Center.

Resumes & CV records

Resumes

Deborah Boles Photo 34

Deborah Boles

Location:
United States
Deborah Boles Photo 35

Executive Office Professional

Location:
Raleigh-Durham, North Carolina Area
Industry:
Executive Office

Publications & IP owners

Us Patents

High-Resolution Melting Analysis

US Patent:
8606529, Dec 10, 2013
Filed:
Mar 26, 2012
Appl. No.:
13/429911
Inventors:
Deborah Boles - Cary NC, US
Kenton C. Hasson - Germantown MD, US
Sami Kanderian - Germantown MD, US
Assignee:
Canon U.S. Life Sciences, Inc. - Rockville MD
International Classification:
G06F 19/00
US Classification:
702 19, 435 6, 435 71, 435 79, 435 911, 435 912, 544245, 544334, 544242, 544152, 536 231, 536 243
Abstract:
The application relates to methods and systems for analysis of dissociation behavior of nucleic acids and identification of nucleic acids. In one aspect, methods and systems are disclosed for identifying a nucleic acid in a sample including an unknown nucleic acid and for detecting a single nucleotide polymorphism in a nucleic acid in a sample. Methods and systems are also disclosed for identification of a nucleic acid in a biological sample including at least one unknown nucleic acid by fitting denaturation data including measurements of a quantifiable physical change of the sample at a plurality of independent sample property points to a function to determine an intrinsic physical value and to obtain an estimated physical change function, and identifying the nucleic acid in the biological sample by comparing the intrinsic physical value for at least one unknown nucleic acid to an intrinsic physical value for a known nucleic acid.

Methods And Systems For Sequential Determination Of Genetic Mutations And/Or Varients

US Patent:
2012008, Apr 12, 2012
Filed:
Jun 2, 2011
Appl. No.:
13/152260
Inventors:
Jacquline Yancy - Laurel MD, US
Lingxia Jiang - Boyds MD, US
Stephanie Buszczak - Rockville MD, US
Renee Howell - Rockville MD, US
Deborah Boles - Cary NC, US
Assignee:
CANON U.S. LIFE SCIENCES, INC. - Rockville MD
International Classification:
C12Q 1/68
US Classification:
435 611
Abstract:
The present invention relates to methods and systems for genome scanning using high resolution melting analysis for identifying mutations and/or variants in genes of interest.

Systems For And Methods Of Hybrid Pyrosequencing

US Patent:
2013017, Jul 11, 2013
Filed:
Jul 6, 2012
Appl. No.:
13/542721
Inventors:
Allen E. Eckhardt - Durham NC, US
Jonathan Benton - Apex NC, US
Deborah Boles - Cary NC, US
Assignee:
ADVANCED LIQUID LOGIC, INC. - Research Triangle Park NC
International Classification:
C12N 15/10
C12Q 1/68
US Classification:
506 5, 506 38
Abstract:
The systems and methods of the invention provide a guided approach to pyrosequencing (i.e., hybrid pyrosequencing). A de novo nucleic acid sequence may compared to a library of possible results and the next nucleotide to be dispensed is selected based on the comparison of the de novo sequence and the library of possible results. In another example, at least the first nucleotide to be dispensed is selected based on a query of a database(s) of non-sequence parameters (e.g., incidence of infection, diagnostic symptoms, sample source) and subsequent dispensations determined based on a comparison of the de novo sequence and the library of possible results (e.g., candidate sequences). The systems and methods of the invention may be performed using a droplet actuator.

Method And Apparatus For Generating Thermal Melting Curves In A Microfluidic Device

US Patent:
2018032, Nov 8, 2018
Filed:
May 25, 2018
Appl. No.:
15/990369
Inventors:
- Rockville MD, US
Deborah John Boles - Cary NC, US
Aaron Rulison - Los Altos CA, US
Wesley B. Dong - Belmont CA, US
Andrew Fabans - Los Gatos CA, US
Allen Boronkay - San Jose CA, US
Edward Donlon - San Jose CA, US
Robert Moti - San Jose CA, US
Michael Slater - Modesto CA, US
Steven A. Sundberg - San Francisco CA, US
Michael R. Knapp - Palo Alto CA, US
Assignee:
Canon U.S. Life Sciences, Inc. - Rockville MD
CALIPER LIFE SCIENCES, INC. - MOUNTAIN VIEW CA
International Classification:
G01N 25/04
B01L 3/00
B01L 7/00
C12Q 1/6862
G01N 21/33
G01N 21/64
C12Q 1/6844
C12Q 1/686
C12Q 1/68
Abstract:
The present invention provides novel methods and devices that employ microfluidic technology to generate molecular melt curves. In particular, the devices and methods in accordance with the invention are useful in providing for the analysis of PCR amplification products.

Systems For And Methods Of Hybrid Pyrosequencing

US Patent:
2015006, Mar 5, 2015
Filed:
Nov 11, 2014
Appl. No.:
14/538379
Inventors:
- San Diego CA, US
Jonathan Benton - Apex NC, US
Deborah Boles - Cary NC, US
Assignee:
ADVANCED LIQUID LOGIC, INC. - San Diego CA
International Classification:
C12N 15/10
C12Q 1/70
C12Q 1/68
US Classification:
506 5, 506 38
Abstract:
The systems and methods of the invention provide a guided approach to pyrosequencing (i.e., hybrid pyrosequencing). A de novo nucleic acid sequence may compared to a library of possible results and the next nucleotide to be dispensed is selected based on the comparison of the de novo sequence and the library of possible results. In another example, at least the first nucleotide to be dispensed is selected based on a query of a database(s) of non-sequence parameters (e.g., incidence of infection, diagnostic symptoms, sample source) and subsequent dispensations determined based on a comparison of the de novo sequence and the library of possible results (e.g., candidate sequences). The systems and methods of the invention may be performed using a droplet actuator.

Method And Apparatus For Generating Thermal Melting Curves In A Microfluidic Device

US Patent:
2014009, Apr 3, 2014
Filed:
Mar 15, 2013
Appl. No.:
13/840994
Inventors:
- Rockville MD, US
Deborah John Boles - Cary NC, US
Aaron Rulison - Los Altos CA, US
Wesley B. Dong - Belmont CA, US
Andrew Fabans - Los Gatos CA, US
Allen Boronkay - San Jose CA, US
Edward Donlon - San Jose CA, US
Robert Moti - San Jose CA, US
Michael Slater - Modesto CA, US
Assignee:
Canon U.S. Life Sciences, Inc. - Rockville MD
International Classification:
C12Q 1/68
US Classification:
435 612, 4352872, 436 94
Abstract:
The present invention provides novel methods and devices that employ microfluidic technology to generate molecular melt curves. In particular, the devices and methods in accordance with the invention are useful in providing for the analysis of PCR amplification products.

Possible Relatives

Cynthia H Boles  David Boles  Dale L Boles  Debbie M Boles  Daniel Boles  Aaron J Boles  Denise Boles  Deborah L Johnson  Deborah A Stamps  Deborah L Stanbery 

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