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John G Yager, 728200 Pennsylvania Rd, Minneapolis, MN 55438

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8200 Pennsylvania Rd, Minneapolis, MN 55438    952-9461163   

Bloomington, MN   

Mocksville, NC   

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Optical Biopsy System And Methods For Tissue Diagnosis

US Patent:
6174291, Jan 16, 2001
Filed:
Mar 9, 1998
Appl. No.:
9/037722
Inventors:
Brain T. McMahon - Minnetonka MN
Chester E. Sievert - Mahtomedi MN
Scott R. Wilson - Maple Grove MN
Ronald R. Zimmermann - Robbinsdale MN
Robert A. Palme - Taylor Falls MN
John G. Yager - Bloomington MN
David R. Walsh - River Falls WI
Assignee:
SpectraScience, Inc. - Plymouth MN
International Classification:
A61B 1000
US Classification:
600564
Abstract:
A system characterizes tissue using fluorescence spectroscopy, such as light-induced fluorescence. Native fluorescence ("autofluorescence") from endogenous tissue without requiring fluorescence-enhancing agents is used to distinguish between normal tissue, hyperplastic tissue, adenomatous tissue, and adenocarcinomas. The system provides endoscopic image enhancement for easy location of a tissue site for optical biopsy tissue characterization. The system allows the use of an integrated endoscopic diagnosis and treatment device for immediate diagnosis and treatment without interchanging equipment and relocating the tissue site. The system is also integrated with existing endoscopy equipment for initiating and displaying the diagnosis. The system provides an adjunctive tool to histopathological tissue classification or, alternatively, further treatment is based on the optical biopsy system diagnosis itself.

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