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Michael A Yaffe, 5023 Glenview Rd, South Orange, NJ 07079

Known as:
Michael A Yapf Mike Yaffe Brian Conrad
Related to:
Warren E Yaffe 81 Andrew J Singer 49

Michael Yaffe Phones & Addresses

23 Glenview Rd, South Orange, NJ 07079   

Windham, NH   

Jersey City, NJ   

7414 6Th St, Brooklyn, NY 11209   

199 Elm St, Dedham, MA 02026    781-2510809   

New York, NY   

Massena, NY   

North Adams, MA   

Work

Company: MASS. INST OF TECHNOLOGY Address: 77 Massachusetts Ave Suite E18-580, Cambridge, MA 02139 Phones: 617-4522103 (Phone) 617-4524978 (Fax)

Education

School / High School: Case Western Reserve University School of Medicine 1989

Languages

English

Awards

Healthgrades Honor Roll

Ranks

Certificate: Critical Care Surgery, 2008
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Mentions for Michael A Yaffe

Career records & work history

Medicine Doctors

Michael Yaffe Photo 1

Dr. Michael B Yaffe, Cambridge MA - MD (Doctor of Medicine)

Specialties:
Critical Care Surgery
Address:
77 Massachusetts Ave Suite E18, Cambridge, MA 02139
617-4524978 (Fax)
MASS. INST OF TECHNOLOGY
77 Massachusetts Ave Suite E18-580, Cambridge, MA 02139
617-4522103 (Phone) 617-4524978 (Fax)
Certifications:
Critical Care Surgery, 2008
General Surgery, 2012
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
77 Massachusetts Ave Suite E18, Cambridge, MA 02139
MASS. INST OF TECHNOLOGY
77 Massachusetts Ave Suite E18-580, Cambridge, MA 02139
Beth Israel Deaconess Medical Center
330 Brookline Avenue, Boston, MA 02215
Education:
Medical School
Case Western Reserve University School of Medicine
Graduated: 1989
Medical School
Deaconess Hospital Havard Med School
Graduated: 1990
Medical School
Deaconess Hospital Havard Med School
Graduated: 1993
Medical School
University Hosps
Graduated: 1993
Medical School
Harvard Longwood Program
Graduated: 1996
Medical School
Harvard Med School
Graduated: 1998

Michael R. Yaffe

Specialties:
Pediatrics
Work:
Dean Clinic
1313 Fish Hatchery Rd, Madison, WI 53715
608-2528000 (phone) 608-2537193 (fax)
Site
Education:
Medical School
Rush Medical College
Graduated: 1979
Procedures:
Circumcision, Colonoscopy, Hearing Evaluation, Upper Gastrointestinal Endoscopy, Vaccine Administration
Conditions:
Acute Bronchitis, Acute Conjunctivitis, Acute Pharyngitis, Acute Sinusitis, Acute Upper Respiratory Tract Infections, Allergic Rhinitis, Anal or Rectal Abscess, Anemia, Anxiety Dissociative and Somatoform Disorders, Anxiety Phobic Disorders, Atopic Dermatitis, Attention Deficit Disorder (ADD), Autism, Bronchial Asthma, Celiac Disease, Chronic Sinusitis, Constipation, Croup, Esophagitis, Gastritis and Duodenitis, Gastroesophageal Reflux Disease (GERD), Gastrointestinal Hemorrhage, Hearing Loss, Inflammatory Bowel Disease (IBD), Iron Deficiency Anemia, Irritable Bowel Syndrome (IBS), Otitis Media, Pertussis, Plantar Warts, Pneumonia, Skin and Subcutaneous Infections, Urinary Incontinence
Languages:
English, Spanish
Description:
Dr. Yaffe graduated from the Rush Medical College in 1979. He works in Madison, WI and specializes in Pediatrics. Dr. Yaffe is affiliated with St Clare Hospital & Health Services and St Marys Hospital.

Michael E. Yaffe

Specialties:
Family Medicine
Work:
McConnell Heart Health Center
3773 Olentangy Riv Rd, Columbus, OH 43214
614-5665356 (phone) 614-5663835 (fax)
Site
Education:
Medical School
Ohio State University College of Medicine
Graduated: 1980
Procedures:
Cardiac Stress Test, Pulmonary Function Tests, Vaccine Administration
Conditions:
Anxiety Phobic Disorders, Disorders of Lipoid Metabolism, Hypothyroidism, Ischemic Heart Disease, Mitral Valvular Disease, Vitamin D Deficiency, Abdominal Hernia, Acute Bronchitis, Acute Conjunctivitis, Acute Myocardial Infarction (AMI), Acute Sinusitis, Acute Upper Respiratory Tract Infections, Alopecia Areata, Alzheimer's Disease, Anal Fissure, Anemia, Angina Pectoris, Anxiety Dissociative and Somatoform Disorders, Atrial Fibrillation and Atrial Flutter, Attention Deficit Disorder (ADD), Bacterial Food Poisoning, Benign Polyps of the Colon, Benign Prostatic Hypertrophy, Bronchial Asthma, Cardiac Arrhythmia, Chronic Renal Disease, Contact Dermatitis, Dementia, Dermatitis, Diabetes Mellitus (DM), Erectile Dysfunction (ED), Esophagitis, Fractures, Dislocations, Derangement, and Sprains, Gastroesophageal Reflux Disease (GERD), Gout, Hallux Valgus, Hearing Loss, Herpes Simplex, Herpes Zoster, Hypertension (HTN), Hyperthyroidism, Inguinal Hernia, Internal Derangement of Knee Cartilage, Intervertebral Disc Degeneration, Iron Deficiency Anemia, Irritable Bowel Syndrome (IBS), Lateral Epicondylitis, Menopausal and Postmenopausal Disorders, Migraine Headache, Non-Toxic Goiter, Obstructive Sleep Apnea, Osteoarthritis, Osteoporosis, Overweight and Obesity, Parkinson's Disease, Peripheral Nerve Disorders, Phlebitis and Thrombophlebitis, Plantar Fascitis, Pneumonia, Prostatitis, Psoriasis, Pulmonary Embolism, Rotator Cuff Syndrome and Allied Disorders, Skin and Subcutaneous Infections, Skin Cancer, Spinal Stenosis, Substance Abuse and/or Dependency, Thyroiditis, Tinea Unguium, Valvular Heart Disease, Varicose Veins, Venous Embolism and Thrombosis, Vitamin B12 Deficiency Anemia
Languages:
English, Spanish
Description:
Dr. Yaffe graduated from the Ohio State University College of Medicine in 1980. He works in Columbus, OH and specializes in Family Medicine. Dr. Yaffe is affiliated with Dublin Methodist Hospital, Grady Memorial Hospital, Grant Medical Center and Riverside Methodist Hospital.

Michael B. Yaffe

Specialties:
General Surgery, Traumatic Surgery
Work:
Beth Israel Deaconess Medical Center Acute Care Surgery
110 Francis St STE 3A, Boston, MA 02215
617-6329922 (phone) 617-6320886 (fax)
Education:
Medical School
Case Western Reserve University School of Medicine
Graduated: 1989
Languages:
English, Spanish
Description:
Dr. Yaffe graduated from the Case Western Reserve University School of Medicine in 1989. He works in Boston, MA and specializes in General Surgery and Traumatic Surgery. Dr. Yaffe is affiliated with Beth Israel Deaconess Medical Center West Campus.
Michael Yaffe Photo 2

Michael Yaffe, Boston MA

Work:
Beth Israel Deaconess Medical Center
330 Brookline Ave, Boston, MA 02215

Resumes & CV records

Resumes

Michael Yaffe Photo 36

Experienced Director Of Operations

Location:
Elkridge, Maryland
Industry:
Political Organization
Work:
FreedoMed Pharmacy - Tampa/St. Petersburg, Florida Area Jun 2009 - Sep 2011
Director of Operations Morgan Stanley - Boca Raton, FL Jun 2008 - Aug 2008
Sales Analyst Navigant Consulting - London, United Kingdom Jun 2007 - Aug 2007
Analyst
Education:
Babson College 2005 - 2009
Bachelor's of Science in Business Administration, Strategic Management
Michael Yaffe Photo 37

Michael Yaffe

Location:
Greater New York City Area
Industry:
Commercial Real Estate

Publications & IP owners

Us Patents

Cell-Based Screening Methods

US Patent:
6730492, May 4, 2004
Filed:
Mar 9, 2002
Appl. No.:
10/093945
Inventors:
Michael H. Cardone - Boston MA
Michael Yaffe - Jamaica Plain MA
Assignee:
Merrimack Pharmaceuticals, Inc. - Cambridge MA
International Classification:
C12Q 148
US Classification:
435 15, 4353201, 435 6, 4352523, 435194, 435 691, 530350
Abstract:
Cell-based screening methods for determining kinase activity are provided. The methods utilize existing cellular pathways that are regulated by kinases. In one embodiment, various components of a ubiquitin-mediated degradation pathway are modified to create an assay that can be used to screen for a molecule that modulates the activity of a kinase of interest that otherwise does not regulate the degradation pathway. In another embodiment, various components of a protein translocation pathway are modified to screen for a molecule that modulates the activity of a kinase of interest that otherwise does not regulate the translocation pathway.

Cell-Based Screening Methods

US Patent:
7083938, Aug 1, 2006
Filed:
Feb 3, 2004
Appl. No.:
10/771035
Inventors:
Michael H. Cardone - Boston MA, US
Michael Yaffe - Jamaica Plain MA, US
Assignee:
Merrimack Pharmaceuticals, Inc. - Cambridge MA
International Classification:
C12Q 1/48
C12N 9/00
C12P 21/06
C07K 1/00
US Classification:
435 15, 435183, 435 691, 530350
Abstract:
Cell-based screening methods for determining kinase activity are provided. The methods utilize existing cellular pathways that are regulated by kinases. In one embodiment, various components of a ubiquitin-mediated degradation pathway are modified to create an assay that can be used to screen for a molecule that modulates the activity of a kinase of interest that otherwise does not regulate the degradation pathway. In another embodiment, various components of a protein translocation pathway are modified to screen for a molecule that modulates the activity of a kinase of interest that otherwise does not regulate the translocation pathway.

Mapkap Kinase-2 As A Specific Target For Blocking Proliferation Of P53-Defective Cells

US Patent:
8440610, May 14, 2013
Filed:
Apr 24, 2007
Appl. No.:
11/789239
Inventors:
Michael B. Yaffe - West Roxbury MA, US
Isaac A. Manke - New York NY, US
Hans Christian Reinhardt - Cambridge MA, US
Assignee:
Massachusetts Institute of Technology - Cambridge MA
International Classification:
A61K 38/16
US Classification:
514 11, 4241331
Abstract:
The present invention relates to compounds and pharmaceutical compositions for treating cellular proliferative disorders, e. g. , in patients having one or more p53-deficient cells, screening assays for identifying such compounds, and methods for treating such disorders.

Cyclic Peptide Libraries And Methods Of Use Thereof To Identify Binding Motifs

US Patent:
2002006, Jun 6, 2002
Filed:
May 28, 1997
Appl. No.:
08/864392
Inventors:
MICHAEL B. YAFFE - SOMERVILLE MA, US
ZHOU SONGYANG - BROOKLINE MA, US
KERMIT L. CARRAWAY - WATERTOWN MA, US
LEWIS C. CANTLEY - CAMBRIDGE MA, US
International Classification:
G01N033/53
C12N009/12
US Classification:
435/007100, 435/194000
Abstract:
Methods for determining an optimal binding motif for a binding compound are provided in which the binding compound is contacted with an oriented degenerate cyclic peptide library (ODCPL) under conditions which allow for interaction between the binding compound and the ODCPL such that a complex is formed between the binding compound and a subpopulation of library members capable of interacting with the binding compound. The subpopulation of library members capable of interacting with the binding compound is then separated from library members that are incapable of interacting with the binding compound. The subpopulation of library members capable of interacting with the binding compound is linearized to form a subpopulation of linearized library members. The amino acid sequence of the subpopulation of linearized library members is determined and an amino acid sequence motif is then determined for an interaction site of the binding compound, based upon the relative abundance of different amino acid residues at each degenerate position within the linearized library members. Oriented degenerate cyclic peptide libraries, and methods for purifying cyclic peptides from linear peptides, are also provided.

Methods For Identifying Ligands Of G-Protein-Coupled Receptors

US Patent:
2002019, Dec 19, 2002
Filed:
Apr 19, 2002
Appl. No.:
10/126430
Inventors:
John Nestor - Bedford MA, US
Carol Wilson - Somerville MA, US
Lewis Cantley - Cambridge MA, US
Michael Yaffe - Jamaica Plain MA, US
Ailan Guo - Medford MA, US
International Classification:
C12Q001/68
G01N033/53
G01N033/543
A61K031/00
US Classification:
435/007100, 435/006000, 436/518000, 514/001000
Abstract:
Methods for identifying ligands of G-protein coupled receptors are provided. Methods generally involve the steps of associating a GPCR having a functional conformation with a support, interacting a naturally-derived sample with the GPCR to bind a molecule in the sample to the GPCR and separating the molecule from the support.

Inhibitors Of Phosphoserine And Phosphothreonine-Proline-Specific Isomerases

US Patent:
2003010, Jun 12, 2003
Filed:
Jul 10, 2002
Appl. No.:
10/193768
Inventors:
Kun Lu - Newton MA, US
Lewis Cantley - Cambridge MA, US
Michael Yaffe - Somerville MA, US
Gunter Fischer - Halle, DE
Assignee:
Max-Planck-Gesellschaft zur Forderung der and Beth Israel Deaconess Medical Center
International Classification:
C12N009/99
US Classification:
514/007000, 435/184000
Abstract:
Inhibitors of phosphoserine- or phosphothreonine-specific pepidyl prolyl isomerases are described.

Cell-Based Screening Methods

US Patent:
2003017, Sep 11, 2003
Filed:
Mar 9, 2002
Appl. No.:
10/093840
Inventors:
Michael Cardone - Boston MA, US
Michael Yaffe - Jamaica Plain MA, US
International Classification:
C12Q001/70
G01N033/53
C12Q001/48
US Classification:
435/005000, 435/007100, 435/015000
Abstract:
Cell-based screening methods for determining kinase activity are provided. The methods utilize existing cellular pathways that are regulated by kinases. In one embodiment, various components of a ubiquitin-mediated degradation pathway are modified to create an assay that can be used to screen for a molecule that modulates the activity of a kinase of interest that otherwise does not regulate the degradation pathway. In another embodiment, various components of a protein translocation pathway are modified to screen for a molecule that modulates the activity of a kinase of interest that otherwise does not regulate the translocation pathway.

Cell-Based Screening Methods

US Patent:
2003017, Sep 11, 2003
Filed:
Mar 9, 2002
Appl. No.:
10/093838
Inventors:
Michael Cardone - Boston MA, US
Michael Yaffe - Jamaica Plain MA, US
International Classification:
C12Q001/66
C12N009/12
C07H021/04
C12P021/02
C12N005/06
US Classification:
435/194000, 435/069700, 435/320100, 435/325000, 536/023200
Abstract:
Cell-based screening methods for determining kinase activity are provided. The methods utilize existing cellular pathways that are regulated by kinases. In one embodiment, various components of a ubiquitin-mediated degradation pathway are modified to create an assay that can be used to screen for a molecule that modulates the activity of a kinase of interest that otherwise does not regulate the degradation pathway. In another embodiment, various components of a protein translocation pathway are modified to screen for a molecule that modulates the activity of a kinase of interest that otherwise does not regulate the translocation pathway.

Isbn (Books And Publications)

Modular Protein Domains

Author:
Michael Yaffe
ISBN #:
3527603611

Possible Relatives

Deborah M Yaffe  Daniel I Yaffe  Eric L Yaffe  Hal Yaffe  Howard D Yaffe  James S Yaffe  Karen K Yaffe  Michael C Last  Michael C Johnson  Michael F Stamps 

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