Patrick G Coffey, 60435 Hardison Way, Los Angeles, CA 90042

7444877, Nov 4, 2008

Aug 20, 2003

10/525279

Mark Bachman - Irvine CA, US
Tao Xu - Irvine CA, US
Patrick Coffey - Mission Viejo CA, US

The Regents of the University of California - Oakland CA

G01D 5/353
H04R 25/02
G01D 21/00

73651, 73655, 381312, 381313, 381328, 2989621, 398134

A directionally-sensitive device for detecting and processing vibration waves includes an array of polymeric optical waveguide resonators positioned between a light source, such as an LED array, and a light detector, such as a photodiode array. The resonators which are preferably oriented substantially perpendicularly with respect to incoming vibration waves, vibrate when a wave is detected, thus modulating light signals that are transmitted between the light source and the light detector. The light detector converts the modulated light into electrical signals which, in a preferred embodiment, are used to drive either the speaker of a hearing aid or the electrode array of a cochlear implant. The device is manufactured using a combination of traditional semiconductor processes and polymer microfabrication techniques.

2004013, Jul 15, 2004

Sep 23, 2003

10/669231

Mark Bachman - Irvine CA, US
Abraham Lee - Irvine CA, US
Nancy Albritton - Irvine CA, US
Brigette Schobert - Irvine CA, US
Noo Jeon - Irvine CA, US
Patrick Coffey - Irvine CA, US
Janos Lanyi - Irvine CA, US
Liang Wu - Irvine CA, US

The Regents of the University of California

G06F019/00
C07K017/00

702/027000, 530/333000

Systems and methods that facilitate crystallization studies through the use of a system of microfluidics, sensors, actuators, and computer instrumentation to enable automated microcrystallization experiments using feedback assisted control and data from a protein crystallization or solubility database. In a preferred embodiment, the crystallization system comprises a database containing quantitative information about the chemical and physical properties under various thermodynamics conditions of the molecule or compounds of interest and a feedback assisted, dynamically controlled chemical system. The chemical system includes a controller that accesses the database and can monitor and control the state of one or more experiments, a software program that uses database information, sensory information, historical information and the like to change the conditions of the experiment, and a crystallization platform that allows computer control and sensing of one or more chemical experiments.