Thomas R Mullinax, 6910233 Glenwood St, Overland Park, KS 66212

7413893, Aug 19, 2008

Jun 9, 2004

10/864086

Mack J. Schermer - Belmont MA, US
Mark Norman Bobrow - Lexington MA, US
Philip R. Buzby - Brockton MA, US
Thomas R. Mullinax - Newton MA, US

PerkinElmer LAS, Inc. - Waltham MA

C12Q 1/68
C12M 1/34

4352872, 435 6, 4352887, 422 8206, 436164

The invention provides an apparatus for interrogating an optical biosensor. The apparatus includes (a) locating means for positioning one or more optical biosensors; (b) calibration means for generating a reference measurement; (c) one or more biosensors for generating one or more sample measurements, the biosensors being substantially planar and removable from the apparatus; (d) a reading means for interrogating biosensor and calibration means, and (e) a transport means for moving one or more of a biosensor, the calibration means and the reading means, whereby the reading means is positioned to interrogate the biosensor and the calibration means.

6066446, May 23, 2000

Jul 14, 1999

9/353515

Thomas R. Mullinax - Newton MA
Mark N. Bobrow - Lexington MA
Michael E. Bembenek - Burlington MA

NEN Life Science Products, Inc. - Boston MA

C12Q 100
C12Q 144
C12Q 116

435 4

Disclosed is a member comprising an interactive material which is covalently bonded to a support body by a linker material. The member can be used as a part of an assay, and the support body may include a scintillator material.

5972595, Oct 26, 1999

Dec 16, 1998

9/212211

Patricia Kasila - Windham NH
Thomas R. Mullinax - Newton MA
Michael E. Bembenek - Burlington MA
Mark N. Bobrow - Lexington MA

NEN Life Science Products, Inc. - Boston MA

C12Q 100
C12Q 144
C12Q 134
C12Q 148

435 4

This invention relates to a hydrophobic layer formed on a solid support, the hydrophobic layer incorporating by hydrophobic interactions an amphipathic enzyme substrate labeled with a reporter on its hydrophilic region, and the use of the same to conduct various enzyme assays without extraction steps.

6030840, Feb 29, 2000

Jun 15, 1998

9/094628

Thomas Robert Mullinax - Newton MA
Margaret R. Cody - Nashua NH
Mark N. Bobrow - Lexington MA

NEN Life Sciences, Inc. - Boston MA

G01N 3320

436 82

A method for the spectroscopic determination of a marker comprises: (a) contacting chelated lanthanide metal ions bound to a marker with a buffered solution comprising a detergent, an enhancer reagent and a polyanion, wherein the buffer maintains the pH of the solution within the range of about 3. 5 to about 11. 5 and the polyanion is present in sufficient concentration such that the lanthanide metal ion disassociates from the chelate complex and reassociates with the enhancer reagent, thereby transferring the lanthanide metal ion into fluorescent form; and (b) determining the amount of lanthanide metal ion liberated from the marker as a measure of the amount of marker present by subjecting the solution to a short radiation pulse and detecting the fluorescence of the lanthanide metal ion after the fluorescence from any background sources substantially has ceased.