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Agnes M Vignery, 75172 Clark Ave, Branford, CT 06405

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172 Clark Ave, Branford, CT 06405    203-4835802    203-4836236   

170 Clark Ave, Branford, CT 06405   

94 New Quarry Rd, Guilford, CT 06437   

139 Pendleton St, New Haven, CT 06511   

172 Clark Ave, Branford, CT 06405    203-4835802   

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Agnes M Vignery

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Position: Professional/Technical

Education

Degree: Graduate or professional degree

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Microsoft Office • Microsoft Word • Customer Service • Leadership • Research • Powerpoint • Management • Training • Nonprofits

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Agnes Vignery

Skills:
Microsoft Office, Microsoft Word, Customer Service, Leadership, Research, Powerpoint, Management, Training, Nonprofits

Publications & IP owners

Us Patents

Method For Fostering Bone Formation And Preservation

US Patent:
7648700, Jan 19, 2010
Filed:
Aug 16, 2007
Appl. No.:
11/839957
Inventors:
Agnes Vignery - Branford CT, US
Nozer M. Mehta - Randolph NJ, US
James P. Gilligan - Union NJ, US
Assignee:
Unigene Laboratories, Inc. - Boonton NJ
Yale University - New Haven CT
International Classification:
A01N 63/00
A61K 38/00
A61F 2/02
US Classification:
424 937, 514 12, 623 1111, 623 1312, 623 1717
Abstract:
A method of inducing bone formation in a subject in need of such inducement comprises the steps of mechanically inducing an increase in osteoblast activity in the subject and elevating blood concentration of at least one bone anabolic agent in the subject. The method steps may be performed in any order, but in sufficient time proximity that the elevated concentration of the anabolic agent and the mechanically induced increase in osteoblast activity overlaps. The method may additionally comprise providing the subject with an elevated blood concentration of at least one antiresorptive agent, wherein the elevated concentration is sufficient to prevent resorption of new bone growth produced due to the osteoblast activity. Use of the method permits targeting of specific bones of the subject for bone production and preservation, faster bone production and earlier discontinuation of bone anabolic pharmaceuticals. Kits adapted for performing the method are provided.

Method For Fostering Bone Formation And Preservation

US Patent:
7776826, Aug 17, 2010
Filed:
Mar 31, 2008
Appl. No.:
12/059662
Inventors:
Agnes Vignery - Branford CT, US
Nozer M. Mehta - Randolph NJ, US
James P. Gilligan - Union NJ, US
Assignee:
Unigene Laboratories, Inc. - Boonton NJ
Yale University - New Haven CT
International Classification:
A61K 38/22
A61K 38/23
A61K 38/29
US Classification:
514 12
Abstract:
A method of inducing bone formation in a subject in need of such inducement comprises the steps of mechanically inducing an increase in osteoblast activity in the subject and elevating blood concentration of at least one bone anabolic agent in the subject. The method steps may be performed in any order, but in sufficient time proximity that the elevated concentration of the anabolic agent and the mechanically induced increase in osteoblast activity overlaps. The method may additionally comprise providing the subject with an elevated blood concentration of at least one antiresorptive agent, wherein the elevated concentration is sufficient to prevent resorption of new bone growth produced due to the osteoblast activity. Use of the method permits targeting of specific bones of the subject for bone production and preservation, faster bone production and earlier discontinuation of bone anabolic pharmaceuticals. Kits adapted for performing the method are provided.

Method For Fostering Bone Formation And Preservation

US Patent:
2005025, Nov 17, 2005
Filed:
May 11, 2005
Appl. No.:
11/128095
Inventors:
Agnes Vignery - Branford CT, US
Nozer Mehta - Randolph NJ, US
James Gilligan - Union NJ, US
International Classification:
A61H001/02
A61K038/17
US Classification:
514012000, 601001000
Abstract:
A method of inducing bone formation in a subject in need of such inducement comprises the steps of mechanically inducing an increase in osteoblast activity in the subject and elevating blood concentration of at least one bone anabolic agent in the subject. The method steps may be performed in any order, but in sufficient time proximity that the elevated concentration of the anabolic agent and the mechanically induced increase in osteoblast activity overlaps. The method may additionally comprise providing the subject with an elevated blood concentration of at least one antiresorptive agent, wherein the elevated concentration is sufficient to prevent resorption of new bone growth produced due to the osteoblast activity. Use of the method permits targeting of specific bones of the subject for bone production and preservation, faster bone production and earlier discontinuation of bone anabolic pharmaceuticals. Kits adapted for performing the method are provided.

Method For Fostering Bone Formation And Preservation

US Patent:
2006009, May 4, 2006
Filed:
Nov 7, 2005
Appl. No.:
11/267987
Inventors:
Agnes Vignery - Branford CT, US
Nozer Mehta - Randolph NJ, US
James Gilligan - Union NJ, US
International Classification:
A61K 38/22
A61K 38/18
A61H 1/02
US Classification:
514012000, 601001000
Abstract:
A method of inducing bone formation in a subject in need of such inducement comprises the steps of mechanically inducing an increase in osteoblast activity in the subject and elevating blood concentration of at least one bone anabolic agent in the subject. The method steps may be performed in any order, but in sufficient time proximity that the elevated concentration of the anabolic agent and the mechanically induced increase in osteoblast activity overlaps. The method may additionally comprise providing the subject with an elevated blood concentration of at least one antiresorptive agent, wherein the elevated concentration is sufficient to prevent resorption of new bone growth produced due to the osteoblast activity. Use of the method permits targeting of specific bones of the subject for bone production and preservation, faster bone production and earlier discontinuation of bone anabolic pharmaceuticals. Kits adapted for performing the method are provided.

Bone Implant Device And Methods Of Using Same

US Patent:
2006029, Dec 28, 2006
Filed:
May 9, 2006
Appl. No.:
11/430752
Inventors:
Agnes Vignery - Branford CT, US
Nozer Mehta - Randolph NJ, US
James Gilligan - Union NJ, US
International Classification:
A61F 2/30
US Classification:
606062000
Abstract:
A bone implant device comprising a plurality of interconnected plate members, at least one plate member defining a plurality of apertures therein adapted for permitting bone growth there through from an interior portion of the bone in which the device is implanted for aiding in securing the device within the interior portion, and wherein the device is configured and adapted to minimize contact with an interior surface of the bone. The device is useful in applications including, but not limited to, repairing bone fractures, modeling bone in growing subjects, service as artificial joints and anchoring prostheses, such as an artificial limb, to a bone stub in the body of a subject.

Method For Fostering Bone Formation And Preservation

US Patent:
2008005, Feb 28, 2008
Filed:
Aug 16, 2007
Appl. No.:
11/839993
Inventors:
Agnes Vignery - Branford CT, US
Nozer Mehta - Randolph NJ, US
James Gilligan - Union NJ, US
International Classification:
A61K 38/22
A61P 19/00
US Classification:
514012000, 514789000
Abstract:
A method of inducing bone formation in a subject in need of such inducement comprises the steps of mechanically inducing an increase in osteoblast activity in the subject and elevating blood concentration of at least one bone anabolic agent in the subject. The method steps may be performed in any order, but in sufficient time proximity that the elevated concentration of the anabolic agent and the mechanically induced increase in osteoblast activity overlaps. The method may additionally comprise providing the subject with an elevated blood concentration of at least one antiresorptive agent, wherein the elevated concentration is sufficient to prevent resorption of new bone growth produced due to the osteoblast activity. Use of the method permits targeting of specific bones of the subject for bone production and preservation, faster bone production and earlier discontinuation of bone anabolic pharmaceuticals. Kits adapted for performing the method are provided.

Method For Fostering Bone Formation And Preservation

US Patent:
2008018, Jul 31, 2008
Filed:
Mar 31, 2008
Appl. No.:
12/059605
Inventors:
Agnes Vignery - Branford CT, US
Nozer M. Mehta - Randolph NJ, US
James P. Gilligan - Union NJ, US
Assignee:
UNIGENE LABORATORIES, INC. - Fairfield NJ
YALE UNIVERSITY - New Haven CT
International Classification:
A61M 37/00
A61B 17/58
A61F 2/28
US Classification:
604131, 606 92, 623 2362
Abstract:
A method of inducing bone formation in a subject in need of such inducement comprises the steps of mechanically inducing an increase in osteoblast activity in the subject and elevating blood concentration of at least one bone anabolic agent in the subject. The method steps may be performed in any order, but in sufficient time proximity that the elevated concentration of the anabolic agent and the mechanically induced increase in osteoblast activity overlaps. The method may additionally comprise providing the subject with an elevated blood concentration of at least one antiresorptive agent, wherein the elevated concentration is sufficient to prevent resorption of new bone growth produced due to the osteoblast activity. Use of the method permits targeting of specific bones of the subject for bone production and preservation, faster bone production and earlier discontinuation of bone anabolic pharmaceuticals. Kits adapted for performing the method are provided.

Methods And Compositions For Fostering And Preserving Bone Growth

US Patent:
2008021, Sep 4, 2008
Filed:
Apr 27, 2007
Appl. No.:
11/796439
Inventors:
Agnes Vignery - Branford CT, US
Nozer M. Mehta - Randolph NJ, US
James P. Gilligan - Union NJ, US
Keiran P. Murphy - Baltimore MD, US
International Classification:
A61F 2/28
A61K 38/18
A61K 31/592
A61B 19/02
A61K 38/22
US Classification:
424423, 514 12, 514167, 206572
Abstract:
A method for augmenting bone in a subject in need thereof including installing within an interior portion of a bone located in the subject a sufficient amount of a biocompatible material to form a scaffold within the bone interior, wherein the scaffold serves as a support for the formation of new bone within the bone interior portion, and administering to the subject a sufficient amount of at least one bone augmentation agent to elevate blood concentration of at least one anabolic agent in the subject. The method may further include administering at least one anti-resorptive agent to the subject in an amount sufficient to substantially prevent resorption of new bone growth. In another embodiment, the method may further include a step of mechanically inducing an increase in osteoblast activity in the subject, wherein the elevation in blood concentration of the anabolic agent and the increase in osteoblast activity at least partially overlap in time.

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