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Alan Robert Saltiel, 707579 Montien Rd, San Diego, CA 92127

Alan Saltiel Phones & Addresses

7579 Montien Rd, San Diego, CA 92127    248-3608481   

1215 Laurel View Dr, Ann Arbor, MI 48105    734-7616906   

2002 Valleyview Dr, Ann Arbor, MI 48105    734-4829552   

Columbia, SC   

14 Hillside Ter, Irvington, NY 10533   

2002 Valleyview Dr, Ann Arbor, MI 48105    734-4782243   

Work

Position: Professional/Technical

Education

Degree: Graduate or professional degree

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Alan Saltiel Photo 18

Alan R. Saltiel

Alan R. Saltiel is the Director of the Life Sciences Institute at the University of Michigan; a professor at the Division of Molecular Genetics at the ...

Us Patents

2-(4-Bromo Or 4-Iodo Phenylamino) Benzoic Acid Derivatives

US Patent:
6492363, Dec 10, 2002
Filed:
Aug 16, 2001
Appl. No.:
09/931596
Inventors:
Stephen Douglas Barrett - Livonia MI
Alexander James Bridges - Saline MI
Donna Reynolds Cody - Saline MI
Annette Marian Doherty - Paris, FR
David Thomas Dudley - Ann Arbor MI
Alan Robert Saltiel - Ann Arbor MI
Mel Conrad Schroeder - Dexter MI
Haile Tecle - Ann Arbor MI
Assignee:
Warner-Lambert Company - Morris Plains NJ
International Classification:
A61K 31535
US Classification:
5142378, 514381, 514428, 514650, 544165, 544241, 544334, 544335, 544376, 564149, 548250, 548252, 562463
Abstract:
Phenylamino benzoic acid, benzamides, and benzyl alcohol derivatives of the formula where R , R , R , R , R , and R are hydrogen or substituent groups such as alkyl, and where R is hydrogen or an organic radical, and Z is COOR , tetrazolyl, CONR R , or CH OR , are potent inhibitors of MEK and, as such, are effective in treating cancer and other proliferative diseases such as inflammation, psoriasis and restenosis, as well as stroke, heart failure, and immunodeficiency disorders.

Treatment Of Asthma With Mek Inhibitors

US Patent:
6696440, Feb 24, 2004
Filed:
Jul 11, 2001
Appl. No.:
09/889091
Inventors:
Alexander James Bridges - Saline MI
David Thomas Dudley - Ann Arbor MI
James Leslie Mobley - Brighton MI
Alan Robert Saltiel - Ann Arbor MI
Assignee:
Warner-Lambert Company - Morris Plains NJ
International Classification:
A61K 31535
US Classification:
5142312, 514277, 514315, 514408, 514438, 514532, 514534, 514535
Abstract:
This invention provides a method of preventing or treating asthma by administering to a patient in need of treatment an effective amount of a selective MEK inhibitor, especially a phenyl amine of Formula I and II:.

4-Bromo Or 4-Iodo Phenylamino Benzhydroxamic Acid Derivatives And Their Use As Mek Inhibitors

US Patent:
6821963, Nov 23, 2004
Filed:
Jun 4, 2002
Appl. No.:
10/163890
Inventors:
Stephen Douglas Barrett - Livonia MI
Alexander James Bridges - Saline MI
Annette Marian Doherty - Paris, FR
David Thomas Dudley - Ann Arbor MI
Alan Robert Saltiel - Ann Arbor MI
Haile Tecle - Ann Arbor MI
Assignee:
Warner-Lambert Company - Morris Plains NJ
International Classification:
A61K 31397
US Classification:
51421015, 540203, 540455, 540485, 51421712, 514335, 514424, 546290, 548541, 558415, 558419, 564163
Abstract:
Phenylamino benzhydroxamic acid derivatives of formula (I) where R , R , R , R , R , and R are hydrogen or substituent groups such as alkyl, and where R is hydrogen or an organic radical, are potent inhibitors of MEK and, as such, are effective in treating cancer and other proliferative diseases such as psoriasis and restenosis.

2-(4-Bromo Or 4-Iodo Phenylamino) Benzoic Acid Derivatives

US Patent:
7019033, Mar 28, 2006
Filed:
Dec 10, 2002
Appl. No.:
10/315654
Inventors:
Stephen Douglas Barrett - Livonia MI, US
Alexander James Bridges - Saline MI, US
Donna Reynolds Cody - Saline MI, US
Annette Marian Doherty - Paris, FR
David Thomas Dudley - Ann Arbor MI, US
Alan Robert Saltiel - Ann Arbor MI, US
Mel Conrad Schroeder - Dexter MI, US
Haile Tecle - Ann Arbor MI, US
Assignee:
Warner-Lambert Company - Morris Plains NJ
International Classification:
A61K 31/5377
A61K 31/496
A61K 31/277
A61K 31/198
US Classification:
514559, 5142358, 514317, 514326, 514381, 514524, 514534, 514567, 558418, 548254, 548950, 546210, 546229, 544392, 544366, 560 19, 562433, 562456
Abstract:
Phenylamino benzoic acid, benzamides, and benzyl alcohol derivatives of the formula.

4-Bromo Or 4-Iodo Phenylamino Benzhydroxamic Acid Derivatives And Their Use As Mek Inhibitors

US Patent:
7169816, Jan 30, 2007
Filed:
Oct 12, 2005
Appl. No.:
11/249543
Inventors:
Stephen Douglas Barrett - Hartland MI, US
Alexander James Bridges - Saline MI, US
Annette Marian Doherty - Nr Canterbury, GB
David Thomas Dudley - Ann Arbor MI, US
Alan Robert Saltiel - Ann Arbor MI, US
Haile Tecle - Ann Arbor MI, US
Assignee:
Warner-Lambert Company - Morris Plains NJ
International Classification:
A61K 31/166
C07D 233/64
US Classification:
514615, 564163
Abstract:
Phenylamino benzhydroxamic acid derivatives of the formula.

Treatment Of Asthma With Mek Inhibitors

US Patent:
2004014, Jul 22, 2004
Filed:
Jan 7, 2004
Appl. No.:
10/753170
Inventors:
Alexander Bridges - Saline MI, US
David Dudley - Ann Arbor MI, US
James Mobley - Brighton MI, US
Alan Saltiel - Ann Arbor MI, US
International Classification:
A61L009/04
US Classification:
424/045000
Abstract:
This invention provides a method of preventing or treating asthma by administering to a patient in need of treatment an effective amount of a selective MEK inhibitor, especially a phenyl amine of Formula I and II:

4-Bromo Or 4-Iodo Phenylamino Benzhydroxamic Acid Derivatives And Their Use As Mek Inhibitors

US Patent:
2005004, Mar 3, 2005
Filed:
Oct 18, 2004
Appl. No.:
10/967427
Inventors:
Stephen Barrett - Livonia MI, US
Alexander Bridges - Saline MI, US
Annette Doherty - Paris, FR
David Dudley - Ann Arbor MI, US
Alan Saltiel - Ann Arbor MI, US
Haile Tecle - Ann Arbor MI, US
International Classification:
C07C239/22
US Classification:
560315000
Abstract:
Phenylamino benzhydroxamic acid derivatives of the formula where R, R, R, R, R, and Rare hydrogen or substituent groups such as alkyl, and where Ris hydrogen or an organic radical, are potent inhibitors of MEK and, as such, are effective in treating cancer and other proliferative diseases such as psoriasis and restenosis.

Ikki Inhibitor Therapies And Screening Methods, And Related Ikki Diagnostics

US Patent:
2009030, Dec 10, 2009
Filed:
Mar 25, 2009
Appl. No.:
12/411226
Inventors:
Alan Saltiel - Ann Arbor MI, US
Merlijn Bazuine - Bethesda MD, US
Assignee:
The Regents of the University of Michigan - Ann Arbor MI
International Classification:
A61K 39/395
A61K 31/4184
A61K 31/7105
C12Q 1/02
C12Q 1/68
G01N 33/68
US Classification:
4241721, 514394, 514 44 A, 435 29, 435 6, 435 721, 436 86
Abstract:
The present invention provides diagnostics, screening methods, and treatment methods related to obesity, insulin resistance, diabetes, weight loss, and related disorders. In particular, the present invention provides methods of treating such conditions with IKKi inhibitors, methods of diagnosing such conditions based on IKKi status, and methods of screening candidate IKKi inhibitors.

Isbn (Books And Publications)

Mechanisms Of Insulin Action

Author:
Alan Saltiel
ISBN #:
0387722033

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