Akhtar A Ali, 63119 Courts Ln, Little Rock, AR 72223

2009009, Apr 16, 2009

Sep 11, 2008

12/209054

Paul F. Coleman - Antioch IL, US
Akhtar X. Ali - Green Oaks IL, US

Abbott Laboratories - Abbott Park IL

C12Q 1/70
G01N 33/53

435 5, 435 71

This invention is related to methods for detecting hepatitis B virus by determining the level of hepatitis B virus surface antigen protein. This invention is also related to methods for detecting mutant hepatitis B virus surface antigen protein and kits for detecting hepatitis B virus.

2010013, Jun 3, 2010

Dec 3, 2009

12/629901

Paul F. Coleman - Antioch IL, US
Akhtar X. Ali - Green Oaks IL, US
Tanseem Ali - Green Oaks IL, US

ABBOTT LABORATORIES - Abbott Park IL

C12Q 1/70

435 5

This invention is related to methods for detecting hepatitis B virus by determining the level of hepatitis B virus surface antigen protein. This invention is also related to methods for detecting mutant hepatitis B virus surface antigen protein and kits for detecting hepatitis B virus.

4339390, Jul 13, 1982

Feb 17, 1981

6/235310

Akhtar Ali - Vernon Hills IL
Paulus T. K. Tsui - Libertyville IL

Abbott Laboratories - North Chicago IL

C07J 500

26039745

The synthesis, resolution, radiolabeling and determination of the superior immunoreactivity of the syn isomer of a derivative of cortisol-21-acetate is described.

4216142, Aug 5, 1980

Dec 18, 1978

5/970767

Akhtar Ali - Vernon Hills IL

Abbott Laboratories - North Chicago IL

C07C10352
C12K 104

2601125R

The present invention encompasses a compound of the formula ##STR1## and the biologically acceptable acid addition salts thereof wherein R is hydrogen, tosyl, carbobenzoxy or benzoyl. These compounds are chromogenic substrates for proteolytic enzymes useful in antithrombin III determination.

4244865, Jan 13, 1981

Dec 3, 1979

6/099376

Akhtar Ali - Vernon Hills IL
Robert G. Hiltibran - Gurnee IL

Abbott Laboratories - North Chicago IL

C07C10352
C07G 700

2601125R

This invention relates to the synthesis and use of novel. alpha. hydroxy tripeptide substrates which are useful in the quantitative determination of proteolytic enzymes such as thrombin and trypsin. In use, the disclosed substrates are hydrolyzed by a proteolytic enzyme to yield a moiety that can be evaluated spectrophotometrically to indicate the quantity of enzyme present.

4221706, Sep 9, 1980

Jun 14, 1979

6/048409

Akhtar Ali - Vernon Hills IL
Jacob J. Plattner - Libertyville IL

Abbott Laboratories - North Chicago IL

C07C10352
C12Q 156
C12Q 138
C12Q 136

2601125R

The present invention comprises compounds of the formula ##STR1## and the biologically acceptable acid addition salts thereof, wherein R. sub. 1 represents hydrogen or lower alkyl having 1 to 4 carbon atoms; R. sub. 2 represents an alkylene having 2 to 4 carbon atoms; R. sub. 3 represents amino or guanidino; R. sub. 4 represents nitrophenyl, methylnitrophenyl, dinitropheyl, naphthyl, or nitronaphtyl; m is 2 or 3; and n is 3 or 4. The compounds of the present invention are analytical reagents useful for measuring proteolytic enzymes such as thrombin and trypsin. The enzymatic hydrolysis of the invention compounds provides a chromogenic amine by which the proteolytic enzyme concentration can be determined spectrophotometrically.

4247453, Jan 27, 1981

Sep 13, 1978

5/942002

Akhtar Ali - Vernon Hills IL

Abbott Laboratories - North Chicago IL

C07C10352

2601125R

The present invention encompasses compounds I and II, mixtures of I and II and acid addition salts thereof wherein R is hydrogen or loweralkyl having 1-3 carbon atoms, as well as compounds wherein the phenol moiety is labeled with. sup. 125 I or. sup. 131 I. The radiolabeled compounds are useful in radiochemical assaying for folic acid. ##STR1##.