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Alireza R Ebrahim, 6223492 Dorielle Ct, Laguna Beach, CA 92677

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23492 Dorielle Ct, Laguna Niguel, CA 92677    949-7166781   

31 Sunswept Mesa, Aliso Viejo, CA 92656    949-8318293   

Trabuco Canyon, CA   

Tuscaloosa, AL   

Semmes, AL   

Vestavia, AL   

Fresno, TX   

Katy, TX   

Mobile, AL   

Foothill Ranch, CA   

Orange, CA   

Irvine, CA   

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Alireza Ebrahim Photo 17

Division R&D Manager At Bio-Rad Laboratories

Publications & IP owners

Us Patents

Reference Control For High-Sensitivity C-Reactive Protein Testing

US Patent:
6548646, Apr 15, 2003
Filed:
Aug 23, 2001
Appl. No.:
09/938409
Inventors:
Alireza Ebrahim - Aliso Viejo CA
Jayshree Parikh - Diamond Bar CA
Warren Eric Vanderslice - Fullerton CA
Assignee:
Bio-Rad Laboratories, Inc. - Hercules CA
International Classification:
A61K 3816
US Classification:
530415, 530380, 530417
Abstract:
Low-concentration reference controls for C-reactive protein assays are prepared from higher-level starting materials by simple filtration using silica-type filter media formerly used for removing lipids. This process avoids the need for antibodies to capture the protein and resuspend it. Surprisingly, the removal of CRP by the silica-type filter media is selective toward CRP, having little or negligible effect on other proteins in the starting matrix, and accordingly little or negligible change in the total protein content.

Apparatus With A Chemical Indicator For Indicating Exposure To An Oxidative Sterilant Or Disinfectant

US Patent:
6551555, Apr 22, 2003
Filed:
Dec 19, 2000
Appl. No.:
09/741633
Inventors:
Patricia A. Antonoplos - Newport Beach CA
Henry K. Hui - Laguna Niguel CA
Alireza Ebrahim - Foothill Ranch CA
Leslie A. Feldman - Calabasas Hills CA
Nitu Kohli - Lake Forest CA
Assignee:
Ethicon, Inc. - New Brunswick NJ
International Classification:
G01N 3112
US Classification:
422 58, 422 57, 422 61, 436 1, 436166
Abstract:
An apparatus for determining exposure to an oxidative sterilant is described. The apparatus includes a chemical indicator for indicating exposure to the oxidative sterilant and a biological indicator for determining the effectiveness of the exposure to the oxidative sterilant. The chemical indicator has a metallic surface with a non-pH sensitive permanent indicator on the surface for indicating exposure to the oxidative sterilant. The chemical indicator may be on a self-contained biological indicator. The biological indicator and chemical indicator may be inside a test pack, where the test pack restricts sterilant flow to the indicators.

Storage-Stable Cellular Whole Blood Composition Containing Elevated Amounts Of D-Dimer

US Patent:
7560283, Jul 14, 2009
Filed:
Jan 27, 2006
Appl. No.:
11/342014
Inventors:
Timothy Ho - Foothill Ranch CA, US
Sholeh Zaminasli - Mission Viejo CA, US
James Cole - Yorba Linda CA, US
Alireza Ebrahim - Laguna Niguel CA, US
Assignee:
Bio-Rad Laboratories, Inc. - Hercules CA
International Classification:
G01N 31/00
US Classification:
436 15
Abstract:
The present invention provides a cellular whole-blood D-dimer composition for use with diagnostic test procedures for D-dimer, and a method of its preparation. The composition comprises human erythrocytes and processed plasma to which D-dimer, and stabilizers, and optionally antimicrobial agents, are added and can be used as a standard and control for D-dimer testing.

Standard/Reference/Control For Blood Coagulation Testing

US Patent:
7588942, Sep 15, 2009
Filed:
Aug 4, 2006
Appl. No.:
11/462436
Inventors:
Timothy Ho - Foothill Ranch CA, US
James Cole - Yorba Linda CA, US
Alireza Ebrahim - Laguna Niguel CA, US
Assignee:
Bio-Rad Laboratories, Inc. - Hercules CA
International Classification:
G01N 33/86
G01N 33/48
US Classification:
436 17, 436 8, 436 18, 436 63, 436 66, 436 69, 436174, 435 2, 435 13, 600369, 73 6441, 2524081
Abstract:
A whole-blood-based substitute composition that is useful in coagulation assays as a standard, reference, control, calibrator, linearity verifier, or training material is prepared by combining a red blood cell lysate that is free of plasma, leukocytes, and platelets with a platelet-free plasma of human origin and an antimicrobial agent.

Stabilized Compositions Containing Natriuretic Peptides

US Patent:
2006018, Aug 17, 2006
Filed:
Feb 14, 2005
Appl. No.:
11/058465
Inventors:
Alireza Ebrahim - Laguna Niguel CA, US
Timothy Ho - Foothill Ranch CA, US
James Cole - Yorba Linda CA, US
Assignee:
Bio-Rad Laboratories, Inc. - Hercules CA
International Classification:
A61K 38/17
US Classification:
514012000
Abstract:
Stabilized compositions of natriuretic peptides comprise the peptide and an effective stabilizing amount of (i) an alkyl or aryl sulfonyl fluoride protease inhibitor, or (ii) benzamidine:

Customized Quality Controls For Analytical Assays

US Patent:
2013022, Aug 29, 2013
Filed:
Aug 24, 2012
Appl. No.:
13/594227
Inventors:
Alireza Ebrahim - Laguna Niguel CA, US
Christopher Spates - Laguna Hills CA, US
Karl De Vore - Coto de Caza CA, US
Assignee:
BIO-RAD LABORATORIES, INC. - Hercules CA
International Classification:
G01N 1/28
US Classification:
2524081
Abstract:
Solid beads each containing a selected quantity of analyte are combined and a liquid base matrix that contains attributes of a biological fluid that is to be assayed, together constitute a kit from which a laboratory technician can, at the point of use, prepare a liquid control for a particular analyte, and preferably a series of such controls at different levels of the same analyte customized for a particular assay.

Biosynthetic Carbohydrate-Deficient Transferrin References

US Patent:
6255047, Jul 3, 2001
Filed:
Feb 28, 2000
Appl. No.:
9/514827
Inventors:
Kristen Toblesky - Yorba Linda CA
Douglas Kang - Mission Viejo CA
Alireza Ebrahim - Foothill Ranch CA
Eric Vanderslice - Fullerton CA
Assignee:
Bio-Rad Laboratories, Inc. - Hercules CA
International Classification:
C12Q 100
G01N 3353
A01N 100
US Classification:
435 4
Abstract:
References, i. e. , solutions of known concentration for use as controls, calibrators, or standards, for assays of carbohydrate-deficient transferring in bodily fluids are obtained from units of bodily fluids from normal healthy individuals by digesting the transferring in these units with exogenous neuraminidase to achieve concentrated CDT solutions, which are then added in preselected proportions to a base matrix to achieve target concentrations.

Method For Indicating Exposure To An Oxidative Sterilant Or Disinfectant

US Patent:
6218189, Apr 17, 2001
Filed:
Apr 13, 1999
Appl. No.:
9/290592
Inventors:
Patricia A. Antonoplos - Newport Beach CA
Henry K. Hui - Laguna Niguel CA
Alireza Ebrahim - Foothill Ranch CA
Leslie A. Feldman - Calabasas Hills CA
Nitu Kohli - Lake Forest CA
Assignee:
Johnson & Johnson Medical, Inc. - New Brunswick NJ
International Classification:
G01N 3112
US Classification:
436 1
Abstract:
A method and apparatus detect exposure to an oxidation-type sterilant using a non-PH-sensitive bleachable dye as a chemical indicator. A change in color indicates exposure to oxidation-type sterilant.

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