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Andrew L Mciver, 427103 Montibillo Pkwy, Durham, NC 27713

Known as:
Andrew Louis Mciver Andrew Mc Iver Andrew L Mclver Andy Mciver Andrew Mc
Related to:
Evelyn J Mckee

Andrew Mciver Phones & Addresses

7103 Montibillo Pkwy, Durham, NC 27713    980-2979465   

Raleigh, NC   

La Jolla, CA   

3839 Sylvan Dr, Wilmington, NC 28403    910-7997992   

Henderson, NV   

106 Fallenwood Ave, Durham, NC 27713   

Work

Company: Center for integrative chemical biology and drug discovery 2012 Position: Postdoctoral research associate

Education

School / High School: North Carolina State University 2007 Specialities: PhD in Chemistry

Skills

Organic synthesis • NMR • IR • LC-MS • HPLC • UV/Vis • GC-MS • TLC • column chromatography (ISCO) • Scifinder • Reaxsys • Chemdraw • MestReNova • Microsoft Office
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Andrew Mciver resumes & CV records

Resumes

Andrew Mciver Photo 36

Senior Research Scientist

Location:
7103 Montibillo Pkwy, Durham, NC 27713
Industry:
Pharmaceuticals
Work:
Center for Integrative Chemical Biology and Drug Discovery in the UNC Eshelman School of Pharmacy - Chapel Hill, NC since Jul 2012
Postdoctoral Research Associate North Carolina State University Aug 2009 - Jul 2012
Research Assistant North Carolina State University Aug 2007 - May 2009
Organic Chemistry TA UC San Diego Sep 2006 - Mar 2007
Organic Chemsitry TA UNC Wilmington Aug 2004 - May 2006
Organic Chemistry TA
Education:
North Carolina State University 2007 - 2012
PhD, Organic Chemistry University of North Carolina at Wilmington 2004 - 2006
M.S, Chemistry University of North Carolina at Wilmington 2000 - 2004
B.S, Chemistry; organic chemistry
Skills:
Organic Synthesis, Nmr, Organic Chemistry, Uv/Vis, Column Chromatography, Hplc, Lc Ms, Chemistry, Ir, High Performance Liquid Chromatography, Tlc, Gc/Ms, Uv Vis, Chemdraw, Microsoft Office, Scifinder, Nmr Spectroscopy, Nucleosides, Chromatography, Laboratory Skills, Problem Solving, Drug Discovery, Communication
Andrew Mciver Photo 37

Andrew Mciver

Andrew Mciver Photo 38

Andrew Mciver

Andrew Mciver Photo 39

Andrew Mciver

Andrew Mciver Photo 40

Andrew Mciver

Andrew Mciver Photo 41

Andrew Mciver - Durham, NC

Work:
Center for Integrative Chemical Biology and Drug Discovery 2012 to 2000
Postdoctoral Research Associate Marbles Kids Museum - Raleigh, NC 2011 to 2012 North Carolina State University 2007 to 2012 University of California San Diego - San Diego, CA 2006 to 2007 University of North Carolina Wilmington - Wilmington, NC 2004 to 2006
Education:
North Carolina State University 2007 to 2012
PhD in Chemistry University of North Carolina Wilmington - Wilmington, NC 2000 to 2006
M.S. in Chemistry departmental and University Honors
B.S. in Chemistry
Skills:
Organic synthesis, NMR, IR, LC-MS, HPLC, UV/Vis, GC-MS, TLC, column chromatography (ISCO), Scifinder, Reaxsys, Chemdraw, MestReNova, Microsoft Office

Publications & IP owners

Us Patents

Pyrrolopyrimidine Nucleosides And Analogs Thereof

US Patent:
2020019, Jun 25, 2020
Filed:
Aug 6, 2019
Appl. No.:
16/533194
Inventors:
- Durham NC, US
- Ann Arbor MI, US
Aaron Leigh DOWNEY - Durham NC, US
John C. DRACH - Ann Arbor MI, US
Andrew Louis MCIVER - Durham NC, US
Bradley David ROBERTSON - Durham NC, US
Dean Wallace SELLESETH - Durham NC, US
Phiroze Behram SETHNA - Durham NC, US
Leroy TOWNSEND - Ann Arbor MI, US
Roy W. WARE - Durham NC, US
International Classification:
C07H 19/14
C07H 19/16
C07D 239/70
Abstract:
The present disclosure provides pyrrolopyrimidine nucleoside analogs of the Formula I, Formula IA, Formula IB, or Formula II and phospholipid conjugates and pharmaceutical compositions thereof wherein Rand A are defined herein. Also presented are methods of treating and/or preventing viral infection and/or viral infection-associated disease or disorder with one or more compounds of Formula I, Formula IA, Formula IB, or Formula II.

Thiazole Derivatives Useful As Mutant Idh1 Inhibitors For Treating Cancer

US Patent:
2019024, Aug 8, 2019
Filed:
Jun 21, 2017
Appl. No.:
16/312206
Inventors:
- Bethesda MD, US
- North Carolina NC, US
Kyle Ryan BRIMACOMBE - Bethesda MD, US
Mindy Irene Emily DAVIS - Rockville MD, US
Yuhong FANG - Rockville MD, US
Matthew HALL - Rockville MD, US
Ajit JADHAV - Chantilly VA, US
Li LIU - Germantown MD, US
Natalia MARTINEZ - Rockville MD, US
Andrew Louis MCIVER - Durham NC, US
Rajan PRAGANI - Gaithersburg MD, US
Jason Matthew ROHDE - Poolesville MD, US
Anton SIMEONOV - Bethesda MD, US
Wei ZHAO - Rockville MD, US
Min SHEN - Boyds MD, US
International Classification:
C07D 417/14
C07D 487/08
A61K 31/4995
A61K 31/496
Abstract:
A compound of Formula II or a pharmaceutically acceptable salt thereof, wherein CyN is a cyclic amine group bound via a nitrogen atom; X is C or N; Rand Rare each independently a halogen, CN, CF, CHF, CHF, a C-C10alkyl group, a C1-Calkoxy group, a di(C-Calkyl)amino; m and n are each independently 1, 2, or 3, and represents either a single bond or a double bond, wherein the racemic mixture of 3-(4-(4-chlorophenyl)thiazol-2-yl)-1-(2-ethyl-5-methoxyphenyl)-6-(2-methylprop-1-en-1-yl)-5-(piperazine-1-carbonyl)pyridin-2(1H)-one atropisomers is excluded.

Mutant Idh1 Inhibitors Useful For Treating Cancer

US Patent:
2019007, Mar 7, 2019
Filed:
Dec 22, 2015
Appl. No.:
15/538570
Inventors:
- Bethesda MD, US
- Chapel Hill NC, US
Rajan Pragani - Gaithersburg MD, US
LI Liu - Germantown MD, US
Mindy Irene Emily Davis - Rockville MD, US
Kyle Ryan Brimacombe - Bethesda MD, US
Min Shen - Boyds MD, US
Anton Simeonov - Bethesda MD, US
Daniel Jason Urban - Rockville MD, US
Ajit Jadhav - Chantilly VA, US
Xiaodong Wang - Chapel Hill NC, US
Andrew Louis McIver - Durham NC, US
International Classification:
C07D 417/04
A61K 31/4709
A61K 31/496
A61K 31/4439
C07D 417/14
A61K 31/4375
C07D 471/04
A61K 31/435
A61K 31/4545
A61K 31/551
A61K 31/437
A61K 31/5377
A61K 31/4704
C07D 215/54
C07D 401/04
A61K 31/506
C07D 215/227
C07D 491/048
C07D 213/82
C07D 487/10
C07D 451/02
A61K 31/46
A61K 31/499
C07D 413/14
Abstract:
Compounds of Formula I and Formula II and the pharmaceutically acceptable salts thereof are disclosed The variables A, B, Y, Z, X, X, Rand Rare disclosed herein. The compounds are useful for treating cancer disorders, especially those involving mutant IDH1 enzymes. Pharmaceutical compositions containing compounds of Formula I or Formula II and methods of treatment comprising administering compounds of Formula I and Formula II are also disclosed.

Pyrrolopyrimidine Nucleosides And Analogs Thereof

US Patent:
2017025, Sep 7, 2017
Filed:
May 18, 2017
Appl. No.:
15/599056
Inventors:
- Durham NC, US
- Ann Arbor MI, US
Aaron Leigh Downey - Durham NC, US
John C. Drach - Ann Arbor MI, US
Andrew Louis McIver - Durham NC, US
Bradley David Robertson - Durham NC, US
Dean Wallace Selleseth - Cary NC, US
Phiroze Behram Sethna - Durham NC, US
Leroy Townsend - Ann Arbor MI, US
Roy W. Ware - Raleigh NC, US
International Classification:
C07H 19/14
C07H 19/16
Abstract:
The present disclosure provides pyrrolopyrimidine nucleoside analogs of the Formula I, Formula IA, Formula IB, or Formula II and phospholipid conjugates and pharmaceutical compositions thereof wherein Rand A are defined herein. Also presented are methods of treating and/or preventing viral infection and/or viral infection-associated disease or disorder with one or more compounds of Formula I, Formula IA, Formula IB, or Formula II.

Possible Relatives

David J Mciver  Dana M Mciver  Daniel M Mciver  Aaron Mciver  Denise M Mciver  Dennis Mciver  Denny J Mciver  Andrew T Last  Andrew R Johnson  Andrew P Stanco 

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