Anthony J Viole, 6824 Camarin St, El Toro, CA 92610

6390969, May 21, 2002

Apr 21, 2000

09/552979

Steven F. Bolling - Ann Arbor MI
Morteza Gharib - San Marino CA
Gabriel Aldea - Seattle WA
Mary Lynn Gaddis - Newport Beach CA
Anthony Viole - Foothill Ranch CA

Orqis Medical Corporation - Lake Forest CA

A61M 110

600 16, 600 17

An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patients heart, and method of using same. One embodiment of the extracardiac system comprises an implantable or portable subcardiac pump, whereby the pump draws blood through an inflow conduit fluidly coupled to a non-primary artery via a cannula and discharges blood through an outflow conduit fluidly coupled to a second non-primary artery via a cannula, wherein at least one of the cannulas projects well into the patients vascular system. The pump may be operated continuously or in a pulsatile fashion, synchronous with the patients heart, thereby potentially reducing the afterload of the heart.

6610004, Aug 26, 2003

Feb 15, 2002

10/078260

Anthony Viole - Foothill Ranch CA
Laksen Sirimanne - Irvine CA
Steven F. Bolling - Ann Arbor MI
Shawn OLeary - Mission Viejo CA
Robert Pecor - Aliso Viejo CA
Ryan Kelly - San Diego CA
Wolfgang Werner - Carlsbad CA
Masoud Beizai - Laguna Hills CA

Orqis Medical Corporation - Lake Forest CA

A61M 110

600 16, 600 17

An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patients heart, and methods of using same. One embodiment of the intravascular extracardiac system comprises a pump with inflow and outflow conduits that are sized and configured to be implantable intravascularly through a non-primary vessel, whereby it may positioned where desired within the patients vasculature. The system comprises a subcardiac pump that may be driven directly or electromagnetically from within or without the patient. The pump is configured to be operated continuously or in a pulsatile fashion, synchronous with the patients heart, thereby potentially reducing the afterload of the heart. In another embodiment, the system is positioned extracorporeally, with the inflow conduit and outflow conduit applied percutaneously to a non-primary vessel for circulating blood to and from the non-primary vessel or between the non-primary vessel and another blood vessel within the patients vasculature.

6761700, Jul 13, 2004

Feb 9, 2001

09/780083

Laksen Sirimanne - Tustin CA
Anthony Viole - Foothill Ranch CA

Orqis Medical Corporation - Lake Forest CA

A61M 3700

604 401, 604 616, 623 136, 623 326

An extracorporeal vascular conduit for circulating blood outside a patients body over an extended period of time in a manner that minimizes risk of thrombosis and complement activation and maximizes the ability of a patient to be ambulatory during recovery stages. The inventive vascular conduit comprises a first biocompatible material and a second synthetic material that is employed over a portion of the biocompatible material that extends outside the patients body when is use. The majority of the portion that extends within the patients body remains uncoated. A third synthetic material is applied around the conduit near the distal end of the second coating material of the catheter to permit a physician to secure the catheter to the patients skin to minimize relative movement.

6889082, May 3, 2005

Nov 6, 2002

10/289467

Steven F. Bolling - Ann Arbor MI, US
Anthony Viole - Foothill Ranch CA, US
Shawn O'Leary - Mission Viejo CA, US

Orqis Medical Corporation - Lake Forest CA

A61M001/10

607 16, 607 17

An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and methods of using same. One embodiment provides a vascular graft that has a first end that is sized and configured to couple to a non-primary blood vessel and a second end that is fluidly coupled to a pump to conduct blood between the pump and the non-primary blood vessel. An outflow conduit is also provided that has a first end sized and configured to be positioned within the same or different blood vessel, whether primary or non-primary, through the vascular graft. The outflow conduit is fluidly coupled to the pump to conduct blood between the pump and the patient. The vascular graft may be connected to the blood vessel subcutaneously to permit application of the extracardiac pumping system in a minimally-invasive procedure.

7048680, May 23, 2006

Jun 6, 2001

09/876281

Anthony Viole - Foothill Ranch CA, US
Laksen Sirimanne - Tustin CA, US
Steven F. Bolling - Ann Arbor MI, US
Shawn O'Leary - Mission Viejo CA, US
Wolfgang Werner - Carlsbad CA, US

Orqis Medical Corporation - Lake Forest CA

A61N 1/362

600 16, 604 43

A multilumen catheter that maximizes the blood flow into and out of the patient's vasculature while also providing for passive and/or active perfusion of tissue downstream of where the catheter resides in the vasculature. The inventive catheter comprises a proximal end, a first distal and a second distal end. Lumens extending from the proximal end to each of these distal ends provide for blood circulation within one or between two blood vessels. At least one aperture in one of the lumens positioned near the proximal end provides for active perfusion of blood to the patient's vasculature downstream of where the aperture resides in the vasculature when the catheter is inserted into the patient for treatment. The inventive catheter may comprise a third lumen positioned entirely within the patient's vasculature, providing passive perfusion of blood to the patient's vasculature downstream of where the third lumen resides in the vasculature when the catheter is inserted into the patient for treatment.

7125376, Oct 24, 2006

Apr 7, 2003

10/408926

Anthony Viole - Foothill Ranch CA, US
Laksen Sirimanne - Irvine CA, US
Steven F. Bolling - Ann Arbor MI, US
Shawn O'Leary - Mission Viejo CA, US
Robert Pecor - Aliso Viejo CA, US
Ryan Kelly - San Diego CA, US
Wolfgang Werner - Carlsbad CA, US
Masoud Beizai - Laguna Hills CA, US

ORQIS Medical Corporation - Lake Forest CA

A61M 1/12

600 16

An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and methods of using same. One embodiment of the intravascular extracardiac system comprises a pump with inflow and outflow conduits that are sized and configured to be implantable intravascularly through a non-primary vessel, whereby it may positioned where desired within the patient's vasculature. The system comprises a subcardiac pump that may be driven directly or electromagnetically from within or without the patient. The pump is configured to be operated continuously or in a pulsatile fashion, synchronous with the patient's heart, thereby potentially reducing the afterload of the heart. In another embodiment, the system is positioned extracorporeally, with the inflow conduit and outflow conduit applied percutaneously to a non-primary vessel for circulating blood to and from the non-primary vessel or between the non-primary vessel and another blood vessel within the patient's vasculature.

7144365, Dec 5, 2006

Dec 5, 2003

10/729026

Steven F. Bolling - Ann Arbor MI, US
Morteza Gharib - San Marino CA, US
Gabriel Aldea - Seattle WA, US
Mary Lynn Gaddis - Newport Beach CA, US
Anthony J. Viole - Foothill Ranch CA, US

Orqis Medical Corporation - Lake Forest CA

A61M 1/10

600 16

An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and method of using same. One embodiment of the extracardiac system comprises a pump configured to be implanted subcutaneously in a minimally-invasive procedure, wherein the pump can draw blood through an inflow conduit, and can discharge blood through an outflow conduit. The pump may be operated continuously or in a pulsatile fashion, synchronous with the patient's heart, thereby potentially reducing the afterload of the heart. The conduits can be housed in a multi-lumen catheter.

7331921, Feb 19, 2008

Jun 28, 2004

10/878592

Anthony Viole - Foothill Ranch CA, US
Laksen Sirimanne - Irvine CA, US
Steven F. Bolling - Ann Arbor MI, US
Shawn O'Leary - Mission Viejo CA, US
Robert Pecor - Aliso Viejo CA, US
Ryan Kelly - San Diego CA, US
Wolfgang Werner - Carlsbad CA, US
Masoud Beizai - Laguna Hills CA, US

Orqis Medical Corporation - Lake Forest CA

A61M 1/12

600 16

An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and methods of using same. One embodiment of the intravascular extracardiac system comprises a pump with inflow and outflow conduits that are sized and configured to be implantable intravascularly through a non-primary vessel, whereby it may positioned where desired within the patient's vasculature. The system comprises a subcardiac pump that may be driven directly or electromagnetically from within or without the patient. The pump is configured to be operated continuously or in a pulsatile fashion, synchronous with the patient's heart, thereby potentially reducing the afterload of the heart. In another embodiment, the system is positioned extracorporeally, with the inflow conduit and outflow conduit applied percutaneously to a non-primary vessel for circulating blood to and from the non-primary vessel or between the non-primary vessel and another blood vessel within the patient's vasculature.