Inventors:
Joseph T. McGinn - Flemington NJ
Suggy S. Chrai - Cranberry NJ
Bogdan Brycki - Mount Laurel NJ
Bawa Singh - Voorhees NJ
Peter Coyle - Newton PA
Gary Santonastaso - Belle Mead NJ
Hoi Cheong Sun - Dayton NJ
Assignee:
Delsys Pharmaceutical Company - Monmouth Junction NJ
International Classification:
A61M 1500
Abstract:
An inhaler disc cartridge comprises a carrier disc with radially outwardly extending resilient fingers, each with a medicament powder dosage. A sealing disc and an indexing ring are bonded to the disc. A cam sequentially and manually deflects a selected finger causing it to snap against an anvil to release the dosage by momentum energy transfer. In other embodiments, a cassette includes a carrier substrate reel of deposited powder dosages with a dosage sealing tape. The substrate comprises a belt with a plurality of transversely extending triangular fingers, each finger tip with a dosage thereon. Each finger is snapped in sequence against an anvil while a clamp secures the belt as the fingers are deflected. The spring fingers are corrugated in one embodiment cooperating with an anvil having channels and a device for inducing agglomeration breakup air streams through the channels. Other embodiments are for impact deflection of a dosage carrying substrate in a cartridge or cassette against an anvil to release the dosages.