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Brock C Christensen, 4571 Maple St, West Lebanon, NH 03784

Brock Christensen Phones & Addresses

71 Maple St, West Lebanon, NH 03784   

Lebanon, NH   

Hanover, NH   

Providence, RI   

Roxbury Crossing, MA   

Stillwater, MN   

Madison, WI   

Mentions for Brock C Christensen

Career records & work history

License Records

Brock John Christensen Rt

Licenses:
License #: 1868 - Expired
Category: Radiography
Issued Date: Sep 27, 1999
Effective Date: Jan 2, 2002
Expiration Date: Sep 30, 2001
Type: Medical Radiographer

Brock Christensen resumes & CV records

Resumes

Brock Christensen Photo 22

Assistant Professor

Location:
71 Maple St, West Lebanon, NH 03784
Industry:
Research
Work:
Dartmouth Medical School since Aug 2011
Assistant Professor
Brown University Jun 2008 - Sep 2011
Postdoctoral Research Associate
Education:
Harvard University 2003 - 2008
Ph.D.
Harvard University School of Public Health 2003 - 2008
University of Wisconsin-Madison 1997 - 2002
BS, Medical microbiology & immunology, French
Brock Christensen Photo 23

Brock Christensen

Publications & IP owners

Us Patents

Methods Of Diagnosing And Treating Carcinomas

US Patent:
2012010, May 3, 2012
Filed:
Mar 5, 2010
Appl. No.:
13/148650
Inventors:
Michele Avissar - Johnston RI, US
Brock C. Christensen - Hanover NH, US
Karl T. Kelsey - Brookline MA, US
Carmen J. Marsit - Grantham NH, US
Assignee:
BROWN UNIVERSITY - Providence RI
International Classification:
A61K 31/7088
A61P 35/00
C12Q 1/68
C40B 30/04
US Classification:
514 44 R, 506 9, 435 612
Abstract:
Methods of diagnosing a carcinoma include comparing the expression of miRNAs in a sample with a control and determining ratios of expression of miRNAs. Methods of treatment include administering a nucleic acid encoding a miR-375 gene product. Methods of optimizing treatment in a subject include determining expression of an miR21-gene product.

Diagnosing, Prognosing, And Early Detection Of Cancers By Dna Methylation Profiling

US Patent:
2011002, Feb 3, 2011
Filed:
Apr 30, 2010
Appl. No.:
12/771036
Inventors:
Brock C. Christensen - Providence RI, US
Karl T. Kelsey - Brookline MA, US
Assignee:
BROWN UNIVERSITY - Providence RI
International Classification:
C40B 30/02
US Classification:
506 8
Abstract:
A method of employing DNA methylation analysis for the diagnosis, prognosis, and prediction of cancer.

Methods For Obtaining Embryonic Stem Cell Dna Methylation Signatures

US Patent:
2020027, Aug 27, 2020
Filed:
Sep 26, 2018
Appl. No.:
16/650761
Inventors:
- Providence RI, US
- Oakland CA, US
- Hanover NH, US
- Lawrence KS, US
Brock C. Christensen - Lebanon NH, US
International Classification:
C12Q 1/6881
Abstract:
Stem cell maturation is a fundamental, yet poorly understood aspect of human development. A DNA methylation signature deeply reminiscent of embryonal stem cells was devised to interrogate the evolving character of multiple human tissues. The cell fraction displaying the signature was found to be highly dependent upon developmental stage (fetal vs adult) and in leukocytes, it described a dynamic transition during the first 5 years of life. Significant individual variation in the embryonic signature of leukocytes was evident at birth, in childhood, and throughout adult life. The genes denoting the signature included transcription factors and proteins intimately involved in embryonic development. The DNA methylation signature traces the developmental origin of cells and informs the study of stem cell heterogeneity in humans under homeostatic and pathologic conditions.

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