Career records & work history
License Records
Abraham C Grossman
Licenses:
License #: 229 - Expired
Category: Nursing Home Administrator
Issued Date: Jan 1, 1971
Category: Nursing Home Administrator
Issued Date: Jan 1, 1971
Abraham I Grossman, 841921 Cripple Creek Ln, Pearland, TX 77581
Abraham Grossman Phones & Addresses
1921 Cripple Creek Ln, Pearland, TX 77581 914-8041148
Gastonia, NC
Dallas, TX
666 Washington Ave, Pleasantville, NY 10570 914-7470077 914-7479108 914-7473967
Tarrytown, NY
New York, NY
1921 Cripple Creek Ln, Pearland, TX 77581 914-4565817
Work
Position:
Executive, Administrative, and Managerial Occupations
Education
Degree:
High school graduate or higher
Mentions for Abraham I Grossman
Publications & IP owners
Us Patents
Compositions, Methods, Kits And Apparatus For Determining The Presence Or Absence Of Target Molecules
US Patent:
6916613, Jul 12, 2005
Filed:
Apr 27, 2001
Appl. No.:
09/844935
Inventors:
Alexander Munishkin - Santa Cruz CA, US
Abraham Grossman - Pleasantville NY, US
Abraham Grossman - Pleasantville NY, US
Assignee:
Q-RNA, Inc. - New York NY
International Classification:
C12Q001/68
C12N015/00
C12N015/63
C12N001/20
C07H021/04
C12N015/00
C12N015/63
C12N001/20
C07H021/04
US Classification:
435 6, 4353201, 4352528, 435174, 435183, 382129, 382133, 382153, 382173, 382286, 382291, 702 19, 702 22, 935 10, 935 24, 935 72, 536 221
Abstract:
The present invention is directed to methods, compositions, kits and apparatus to identify and detect the presence or absence of target analytes. The embodiments of the present invention have utility in medical diagnosis and analysis of various chemical compounds in specimens and samples, as well as the design of test kits and apparatus for implementing such methods.
Compositions And Methods For Binding Agglomeration Proteins
US Patent:
7232807, Jun 19, 2007
Filed:
Apr 22, 2005
Appl. No.:
11/112953
Inventors:
Abraham Grossman - Pleasantville NY, US
Valentine M. Kryukov - Puschino, RU
Brian Neil Zeiler - Washington Township NJ, US
Valentine M. Kryukov - Puschino, RU
Brian Neil Zeiler - Washington Township NJ, US
Assignee:
Oligomerix, Inc. - New York NY
International Classification:
C07H 21/02
C07H 21/00
A61K 31/70
C12N 15/11
C07H 21/00
A61K 31/70
C12N 15/11
US Classification:
514 44, 536 256, 536 231, 977704
Abstract:
Amplibody compositions and methods used to interact with agglomeration proteins are disclosed herein. Compositions herein comprise one or more DNA or RNA molecules having affinity for at least one agglomeration protein. The nucleic acid component is a naturally or non-naturally occuring molecule with twenty or more ribonucleotide bases. For RNA, at least one nucleotide sequence portion of this RNA molecule has affinity to at least one consensus sequence present in the agglomeration RNA-binding protein. The portion of nucleotide sequence of RNA having affinity for agglomeration proteins is a sequence that is derived from either and RNA virus, and RNA agglomeration proteins is a sequence that is derived from either and RNA virus, an RNA phage, a messenger RNA (“mRNA”), a ribosomal RNA (“rRNA), a transfer RNA (“tRNA”), a sequence that is received as a template by one or more RNA dependent RNA polymerases, or a combination thereof. Methods disclosed herein are directed towards detecting the presence of one or more agglomeration proteins in a sample matrix using the amplibody compositions described herein.
Methods, Compositions And Apparatus For Making Nucleic Acid Molecules Having A Selected Affinity To A Target Molecule
US Patent:
2003008, May 8, 2003
Filed:
Dec 29, 2000
Appl. No.:
09/752231
Inventors:
Abraham Grossman - Pleasantville NY, US
Assignee:
Q-RNA, Inc.
International Classification:
C12Q001/68
C12P019/34
C12M001/34
C12P019/34
C12M001/34
US Classification:
435/006000, 435/091200, 435/287200
Abstract:
The present invention is directed to methods, compositions, kits and devices for making a nucleic acid having selected affinity to a target molecule. One embodiment of the present invention is a method of making a replicatable nucleic acid template having a selected affinity to a target. The method comprises the step of applying a selection to a first generation comprising at least one replicatable nucleic acid template as the replicatable nucleic acid template is replicated by a nucleic acid polymerase to form at least one subsequent generation comprising a replicatable nucleic acid template. The selection is based on the affinity of the replicatable nucleic template of different generations to the target. The nucleic acid polymerase introduces genetic variability between generations of the replicatable nucleic acid template to produce replicatable nucleic acid templates having different affinities to the target. The replicatable nucleic acid templates are separated on the basis of the affinity of the replicatable nucleic acid template to the target.
Compositions And Methods For Binding Agglomeration Proteins
US Patent:
2004000, Jan 8, 2004
Filed:
Jun 26, 2003
Appl. No.:
10/343694
Inventors:
Abraham Grossman - New York NY, US
Valentine Kryukov - New York NY, US
Brian Zeiler - Twp. of Washington NJ, US
Valentine Kryukov - New York NY, US
Brian Zeiler - Twp. of Washington NJ, US
International Classification:
C12Q001/70
C12Q001/68
C07H021/04
C12N007/00
C12N015/86
C12Q001/68
C07H021/04
C12N007/00
C12N015/86
US Classification:
435/005000, 435/006000, 435/456000, 435/235100, 536/023720
Abstract:
Amplibody compositions and methods used to interact with agglomeration proteins are disclosed herein. Compositions herein comprise one or more DNA or RNA molecules having affinity for at least one agglomeration protein. The nucleic acid component is a naturally or non-naturally occuring molecule with twenty or more ribonucleotide bases. For RNA, at least one nucleotide sequence portion of this RNA molecule has affinity to at least one consensus sequence present in the agglomeration RNA-binding protein. The portion of nucleotide sequence of RNA having affinity for agglomeration proteins is a sequence that is derived from either and RNA virus, and RNA agglomeration proteins is a sequence that is derived from either and RNA virus, an RNA phage, a messenger RNA (“mRNA”), a ribosomal RNA (“rRNA”), a transfer RNA (“tRNA”), a sequence that is received as a template by one or more RNA dependent RNA polymerases, or a combination thereof. Methods disclosed herein are directed towards detecting the presence of one or more agglomeration proteins in a sample matrix using the amplibody compositions described herein.
Methods Of Detection Employing Immuno-Q-Amp Technology
US Patent:
2005021, Sep 29, 2005
Filed:
Nov 9, 2004
Appl. No.:
10/985183
Inventors:
Abraham Grossman - New York NY, US
Assignee:
Q-RNA, Inc. - New York NY
International Classification:
C12Q001/68
G01N033/53
G01N033/567
G01N033/53
G01N033/567
US Classification:
435006000, 435007200
Abstract:
Disclosed herein are methods of detecting target molecules from a complex sample using a modified affinity ligand. In particular, the modified affinity ligand is an antibody specific for the target and has conjugated to it a nucleic acid molecule. This conjugated nucleic acid molecule serves as a template for a replicase that can replicate the template a billion-fold in an matter of minutes. The replication products then serve to facilitate a detectable signal indicating the presence of the target in the sample.
Compositions And Methods For Binding Agglomeration Proteins
US Patent:
2005026, Dec 1, 2005
Filed:
Apr 22, 2005
Appl. No.:
11/112929
Inventors:
Abraham Grossman - Pleasantville NY, US
Valentine Kryukov - Puschino, RU
Brian Zeiler - Washington Township NJ, US
Valentine Kryukov - Puschino, RU
Brian Zeiler - Washington Township NJ, US
Assignee:
Q-RNA - New York NY
International Classification:
C12Q001/70
C12Q001/68
C12Q001/68
US Classification:
435005000, 435006000
Abstract:
Amplibody compositions and methods used to interact with agglomeration proteins are disclosed herein. Compositions herein comprise one or more DNA or RNA molecules having affinity for at least one agglomeration protein. The nucleic acid component is a naturally or non-naturally occuring molecule with twenty or more ribonucleotide bases. For RNA, at least one nucleotide sequence portion of this RNA molecule has affinity to at least one consensus sequence present in the agglomeration RNA-binding protein. The portion of nucleotide sequence of RNA having affinity for agglomeration proteins is a sequence that is derived from either and RNA virus, and RNA agglomeration proteins is a sequence that is derived from either and RNA virus, an RNA phage, a messenger RNA (“mRNA”), a ribosomal RNA (“rRNA), a transfer RNA (“tRNA”), a sequence that is received as a template by one or more RNA dependent RNA polymerases, or a combination thereof. Methods disclosed herein are directed towards detecting the presence of one or more agglomeration proteins in a sample matrix using the amplibody compositions described herein.
Compositions And Methods For Binding Agglomeration Proteins
US Patent:
2005026, Dec 1, 2005
Filed:
Apr 22, 2005
Appl. No.:
11/112954
Inventors:
Abraham Grossman - Pleasantville NY, US
Valentine Kryukov - Puschino, RU
Brian Zeiler - Washington Township NJ, US
Valentine Kryukov - Puschino, RU
Brian Zeiler - Washington Township NJ, US
Assignee:
Q-RNA - New York NY
International Classification:
C12Q001/70
C12Q001/68
C12Q001/68
US Classification:
435005000, 435006000
Abstract:
Amplibody compositions and methods used to interact with agglomeration proteins are disclosed herein. Compositions herein comprise one or more DNA or RNA molecules having affinity for at least one agglomeration protein. The nucleic acid component is a naturally or non-naturally occuring molecule with twenty or more ribonucleotide bases. For RNA, at least one nucleotide sequence portion of this RNA molecule has affinity to at least one consensus sequence present in the agglomeration RNA-binding protein. The portion of nucleotide sequence of RNA having affinity for agglomeration proteins is a sequence that is derived from either and RNA virus, and RNA agglomeration proteins is a sequence that is derived from either and RNA virus, an RNA phage, a messenger RNA (“mRNA”), a ribosomal RNA (“rRNA”), a transfer RNA (“tRNA”), a sequence that is received as a template by one or more RNA dependent RNA polymerases, or a combination thereof. Methods disclosed herein are directed towards detecting the presence of one or more agglomeration proteins in a sample matrix using the amplibody compositions described herein.
Methods, Compositions And Apparatus For Making Nucleic Acid Molecules Having A Selected Affinity To A Target Molecule
US Patent:
2005027, Dec 8, 2005
Filed:
May 24, 2005
Appl. No.:
11/135673
Inventors:
Abraham Grossman - Pleasantville NY, US
Assignee:
Q-RNA, Inc. - New York NY
International Classification:
C12Q001/68
C12P019/34
C12P019/34
US Classification:
435006000, 435091200
Abstract:
The present invention is directed to methods, compositions, kits and devices for making a nucleic acid having selected affinity to a target molecule. One embodiment of the present invention is a method of making a replicatable nucleic acid template having a selected affinity to a target. The method comprises the step of applying a selection to a first generation comprising at least one replicatable nucleic acid template as the replicatable nucleic acid template is replicated by a nucleic acid polymerase to form at least one subsequent generation comprising a replicatable nucleic acid template. The selection is based on the affinity of the replicatable nucleic template of different generations to the target. The nucleic acid polymerase introduces genetic variability between generations of the replicatable nucleic acid template to produce replicatable nucleic acid templates having different affinities to the target. The replicatable nucleic acid templates are separated on the basis of the affinity of the replicatable nucleic acid template to the target.
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