Charles F Simmons, 70Los Angeles, CA

2010029, Nov 18, 2010

May 1, 2008

12/598259

Ozlem Equils - Sherman Oaks CA, US
Calvin Hobel - Palos Verdes Estates CA, US
Charles F. Simmons - Los Angeles CA, US

CEDARS-SINAI MEDICAL CENTER - Los Angeles CA

A61K 38/06
A61P 15/00

514 219

Apoptotic processes induced by infection of, or injury to, fetal and placental tissues have been implicated in preterm delivery. Thus, modulation of apoptotis constitutes a strategy for improving pregnancy outcome in women with intrauterine infections. Caspase inhibitors, including the pancaspase inhibitor Z-VAD-FMK, can be used to prevent apoptosis and, thus, prevent preterm delivery. Accordingly, compositions and methods comprising caspase inhibitors for prevention of preterm delivery are provided.

2012023, Sep 20, 2012

Dec 7, 2010

13/512212

Ozlem Equils - Sherman Oaks CA, US
Charles F. Simmons - Los Angeles CA, US

Cedars-Sinai Medical Center - Los Angeles CA

C40B 30/04
C40B 40/10
C12Q 1/06
G01N 33/566
C12Q 1/68

506 9, 435 792, 435 611, 435 39, 506 18

The invention relates to biomarkers associated with preterm delivery. More specifically, the invention provides methods of measuring biomarkers found in women that are at risk for preterm delivery.

2014005, Feb 20, 2014

Mar 13, 2012

14/003334

Ozlem Equils - Sherman Oaks CA, US
Charles F. Simmons - Los Angeles CA, US

CEDARS-SINAI MEDICAL CENTER - Los Angeles CA

G01N 33/68

506 9, 435 71, 435 724, 435 792, 435 61, 530350

The invention relates to biomarkers associated with preterm delivery. More specifically, the invention provides methods of measuring biomarkers including but not limited to cytokines, cytokine receptors, cytokine receptor antagonists, chemokines, chemokine receptors, and/or chemokine receptor antagonists found in women that are at risk for preterm delivery. The diagnostic methods may be performed on whole blood.

6141175, Oct 31, 2000

Oct 8, 1997

8/946805

Ara W. Nazarian - Tustin CA
Charles W. Simmons - Phoenix AZ
Thao P. Trieu - Redwood City CA
Richard K. Wong - San Jose CA

Western Digital Corporation - Irvine CA

G11B 5596

360 7704

A method in a magnetic storage disk drive for independently learning and thereafter canceling repeatable runout that is written to the servo fields of each servo track during the servo writing process. The method does not require a servo writer because the disk drive may independently detect the runout without spinning out of control in response to such runout by operating its servo control loop in a low bandwidth mode so that it is less responsive to the higher frequency components of the runout, and by removing the effect of the DC component of the runout or selected harmonics on each revolution. The method takes several revolutions to "learn" the servo wedges of a current track by initializing a wedge runout value for each servo wedge and an average uncorrected runout value and then successively developing an interim wedge runout estimate for each servo wedge by adding a fractional portion. lambda. of a raw position error signal to a fractional portion (1-. lambda. ) of the wedge runout value, computing a corrected position error signal by subtracting the interim wedge runout estimate from the raw position error signal, and computing a new wedge runout value by subtracting the average uncorrected runout value from the interim wedge runout estimate and, subsequent to each revolution, updating the average uncorrected runout value.

6067206, May 23, 2000

Nov 18, 1997

8/972655

Richard W. Hull - Laguna Hills CA
David B. Joan - Trabuco Canyon CA
Charles R. Patton - Murrieta CA
Vafa James Rakshani - Laguna Beach CA
Charles W. Simmons - Phoenix AZ

Western Digital Corporation - Irvine CA

G11B 5596

360 7708

A disk drive controller having a microprocessor and a sampled signal head positioning system measures and stores the relative rotational offsets between heads arranged in a stacked relationship and respective servo wedges on different disk surfaces. The offsets are stored in a table and subsequently applied to a servo wedge detection circuit to ensure that a next sequential wedge is detected after a head switch.

5513749, May 7, 1996

May 11, 1995

8/439494

Charles B. Simmons - Carson CA

B65D 8557

2063081

A storage case for holding approximately five compact discs (CDs) which is approximately equal in exterior dimensions to that of a standard jewel case of the type most widely used in the U. S. for holding a single CD. The invention addresses both a factory manufactured case, and components for modifying an existing standard CD jewel case. The rectangular case is properly dimensioned and shaped to cooperatively function with the most common currently available and widely used CD jewel case storage racks and boxes. The case includes rigidly structured top and bottom case halves hingedly attached to one another for allowing relative pivotal movement for opening and closing the case. A binder member removably snaps into the interior of the bottom half adjacent the hinge side. The binder member includes multiple extensions for retaining five preferably clear plastic flexible sleeves that retain a CD each. The sleeves include apertures along one edge for receipt and retention by the binder member extensions, and can be flipped through similar to pages of a book when the case is open.

6310742, Oct 30, 2001

Jun 26, 2000

9/603809

Ara W. Nazarian - Tustin CA
Charles W. Simmons - Phoenix AZ
Thao P. Trieu - Redwood City CA
Richard K. Wong - San Jose CA

Western Digital Technologies, Inc. - Lake Forest CA

G11B 5596

360 7704

A method in a magnetic storage disk drive for independently learning and thereafter canceling repeatable runout that is written to the servo fields of each servo track during the servo writing process. The method does not require a servo writer because the disk drive may independently detect the runout without spinning out of control in response to such runout by operating its servo control loop in a low bandwidth mode so that it is less responsive to the higher frequency components of the runout, and by removing the effect of the DC component of the runout or selected harmonics on each revolution. The method takes several revolutions to "learn" the servo wedges of a current track by initializing a wedge runout value for each servo wedge and an average uncorrected runout value and then successively developing an interim wedge runout estimate for each servo wedge by adding a fractional portion. lambda. of a raw position error signal to a fractional portion (1-. lambda. ) of the wedge runout value, computing a corrected position error signal by subtracting the interim wedge runout estimate from the raw position error signal, and computing a new wedge runout value by subtracting the average uncorrected runout value from the interim wedge runout estimate and, subsequent to each revolution, updating the average uncorrected runout value.

2017024, Aug 31, 2017

Sep 18, 2015

15/512109

- Menifee CA, US
Charles W. SIMMONS - Menifee CA, US

G06Q 50/00
H04L 29/08
G06F 17/30

Systems and methods useful in transmitting information from celebrity-providers to fan-users are provided. System and methods include a global data structure representing at least one celebrity-provider profile, an internal data structure coupled to the global data structure, and a computer server coupled to the global data structure and the internal data structure. The internal data structure includes a handler class programmed to convert raw celebrity-provider data into organized celebrity-provider data, at least one model representing celebrity-provider data, at least one view attached to a corresponding model and being programmed to retrieve the celebrity-provider data from the corresponding model, and a controller coupling the system to one or more fan-users. The model accesses the at least one handler class. The controller is programmed to provide at least one view to one or more fan-users. The internal data structure is programmed to combine multi-platform online assets of a celebrity-provider into a single uniform network accessible by fan-users.