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Charles Hadley Spilman, 8312751 Kelly Sands Way, Fort Myers, FL 33908

Charles Spilman Phones & Addresses

12751 Kelly Sands Way, Fort Myers, FL 33908   

7330 Estero Blvd, Ft Myers Bch, FL 33931   

9944 Springwood Dr, Kalamazoo, MI 49009   

934 Osborne St, Kalamazoo, MI 49001   

Wheat Ridge, CO   

Lee, FL   

Richland, MI   

Mentions for Charles Hadley Spilman

Charles Spilman resumes & CV records

Resumes

Charles Spilman Photo 8

Charles Spilman

Charles Spilman Photo 9

Charles Spilman

Location:
Fort Myers, FL
Industry:
Pharmaceuticals
Education:
University of Massachusetts Amherst 1965 - 1969
Doctorates, Doctor of Philosophy, Biology, Philosophy
Clark University 1961 - 1965
Bachelors, Bachelor of Arts, Biology
University of Massachusetts
Skills:
In Vivo Pharmaceutical Testing, In Vitro Pharmaceutical Testing, Project Planning, Project Management, Problem Analysis, Problem Solving, Scientific Writing, Personnel Management, Budget Process, Performance Appraisal, Performance Improvement, Performance Management

Publications & IP owners

Us Patents

Lipophilic Polyamines Useful For Treating Hypercholesterolemia

US Patent:
5192798, Mar 9, 1993
Filed:
Aug 16, 1990
Appl. No.:
7/566441
Inventors:
James W. Aiken - Plainwell MI
Charles H. Spilman - Kalamazoo MI
Edward W. Thomas - Kalamazoo MI
Assignee:
The Upjohn Company - Kalamazoo MI
International Classification:
A61K 3116
C07C21118
US Classification:
514462
Abstract:
This invention relates to novel lipophilic polyamines of formula I, the method of using these compounds to treat hypercholesterolemia, and intermediates thereto. Z. sub. 1 --(CH. sub. 2). sub. n --Y. sub. 1 --X. sub. 1 --R. sub. 1 I.

Pyrazoloazepino Substituted Oximes Useful As Anti-Atherosclerosis And Anti-Hypercholesterolemic Agents

US Patent:
5597816, Jan 28, 1997
Filed:
Jun 6, 1995
Appl. No.:
8/468158
Inventors:
Scott D. Larsen - Kalamazoo MI
Charles H. Spilman - Kalamazoo MI
Assignee:
The Upjohn Company - Kalamazoo MI
International Classification:
A61K 3133
A61K 3155
C07D22314
C07D22504
US Classification:
514183
Abstract:
Pyrazoloazepino-substituted oximes, having the formula ##STR1## wherein R is ##STR2## where R. sup. 5 is --(CH. sub. 2). sub. c -- and c is 3-6 are disclosed. These compounds are useful for the treatment of atherosclerosis and hypercholesterolemia.

Pyrrolidino-Substituted Oximes Useful As Anti-Atherosclerosis And Anti-Hypercholesterolemic Agents

US Patent:
5523318, Jun 4, 1996
Filed:
Jun 6, 1995
Appl. No.:
8/466181
Inventors:
Scott D. Larsen - Kalamazoo MI
Charles H. Spilman - Kalamazoo MI
Assignee:
The Upjohn Company - Kalamazoo MI
International Classification:
A61K 31415
C07D23154
US Classification:
514406
Abstract:
Pyrrolidinopyrazole-substituted oximes having the formula ##STR1## are disclosed wherein R. sup. 1, R. sup. 2, R. sup. 3, R. sup. 4, R. sup. 5 and a are as described in the claims for the treatment of atherosclerosis and hypercholesterolemia.

Pyridino Substituted Oximes Useful As Anti-Atherosclerosis And Anti-Hypercholesterolemic Agents

US Patent:
5565468, Oct 15, 1996
Filed:
Sep 27, 1994
Appl. No.:
8/313684
Inventors:
Scott D. Larsen - Kalamazoo MI
Charles H. Spilman - Kalamazoo MI
Assignee:
The Upjohn Company - Kalamazoo MI
International Classification:
A61K 3144
C07D47104
US Classification:
514300
Abstract:
Imidazopyridino- and pyrazolopyridino- substituted oximes are disclosed having the formulas ##STR1## wherein R. sup. 1, R. sup. 2, R. sup. 3, R. sup. 4, R. sup. 5 and a are as described in the claims. for the treatment of atherosclerosis and hypercholesterolemia.

Fine-Milled Colestipol Hydrochloride

US Patent:
5520932, May 28, 1996
Filed:
Aug 3, 1994
Appl. No.:
8/289321
Inventors:
Vincent E. McCurdy - Vicksburg MI
Charles H. Spilman - Kalamazoo MI
Assignee:
The Upjohn Company - Kalamazoo MI
International Classification:
A61K 914
US Classification:
424501
Abstract:
The present invention provides a novel fine milled form of a known pharmaceutical composition, colestipol hydrochloride. This fine milled form of colestipol hydrochloride yields pharmaceutically elegant dosage forms exhibiting increased potency, including non-gritty oral powders and high dose oral tablets (e. g. , 1000 mg tablets). Conventional colestipol hydrochloride was heretofore available in spherical granules which produced less elegant (gritty) oral suspensions and oral tablets with substantially lower doses of drug (e. g. , ca 500 mg).

Isbn (Books And Publications)

Regulatory Mechanisms Of Male Reproductive Physiology

Author:
Charles Hadley Spilman
ISBN #:
0444167161

Novel Aspects Of Reproductive Physiology: Proceedings Of The Seventh Brook Lodge Workshop On Problems Of Reproductive Physiology

Author:
Charles Hadley Spilman
ISBN #:
0470263687

Novel Aspects Of Reproductive Physiology: Proceedings Of The Seventh Brook Lodge Workshop On Problems Of Reproductive Physiology

Author:
Charles Hadley Spilman
ISBN #:
0893350508

The Providence Journal, 150 Years

Author:
Charles H. Spilman
ISBN #:
0937550019

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