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Cheryl R Heiner, 69112 Sueno Camino, La Honda, CA 94020

Cheryl Heiner Phones & Addresses

1800 Portola State Park Rd, La Honda, CA 94020    650-9419679   

1952 Ticonderoga Dr, San Mateo, CA 94402    650-2122673   

Mill Valley, CA   

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Cheryl R Heiner

Linkedin

Work

Company: Pacific biosciences Jan 1, 2012 Position: Principal scientist, applications and market development

Education

School / High School: Lindbergh High School

Skills

Dna Sequencing • Sequencing • Biotechnology • Dna • Genomics • Molecular Biology • Assay Development • R&D • Electrophoresis • Life Sciences • Genetics • Sequence Analysis • Rna Isolation • Target Identification • Lifesciences • Purification • Commercialization • Elisa • Immunology • Product Development • Immunoassays • Flow Cytometry • Functional Management • Genome Sequencing • Product R&D • Molecular Genetics • Research and Development

Industries

Biotechnology

Mentions for Cheryl R Heiner

Cheryl Heiner resumes & CV records

Resumes

Cheryl Heiner Photo 11

Principal Scientist, Applications And Market Development

Location:
P/O Box 1675, Granite Falls, WA
Industry:
Biotechnology
Work:
Pacific Biosciences
Principal Scientist, Applications and Market Development
Pacific Biosciences Jan 2006 - Sep 2011
Director and Senior Director, Sequencing
Life Technologies 1982 - 2005
Research Scientist To Scientific Fellow
Education:
Lindbergh High School
Indiana University
Indiana University Bloomington
Skills:
Dna Sequencing, Sequencing, Biotechnology, Dna, Genomics, Molecular Biology, Assay Development, R&D, Electrophoresis, Life Sciences, Genetics, Sequence Analysis, Rna Isolation, Target Identification, Lifesciences, Purification, Commercialization, Elisa, Immunology, Product Development, Immunoassays, Flow Cytometry, Functional Management, Genome Sequencing, Product R&D, Molecular Genetics, Research and Development

Publications & IP owners

Us Patents

Nucleic Acid Probes And Method For Detecting Ureaplasma Urealyticum

US Patent:
6531583, Mar 11, 2003
Filed:
Dec 8, 2000
Appl. No.:
09/601198
Inventors:
Gail H. Cassell - Carmel IN
Ellson Y. Chen - Burlingame CA
Jennifer S. Glass - Indianapolis IN
John I. Glass - Indianapolis IN
Cheryl R. Heiner - La Honda CA
Elliot Lefkowitz - Birmingham AL
Assignee:
UAB Research Foundation, The - Birmingham AL
International Classification:
C07H 1900
US Classification:
536 221, 435 6, 435 71, 435 911, 435 912, 4353201, 536 231, 536 243, 536 2431, 536 2432, 536 2433
Abstract:
A method of detecting a nucleic acid sequence in serovar 3 includes the steps of isolating a specimen containing nucleic acid; and analyzing the specimen with an assay such as in situ hybridization, Southern blotting, single strand conformational polymorphism, restriction endonuclease fingerprinting (REF), PCR amplification, 5รข nuclease assay (TaqMan PCR), and DNA-chip analysis using the nucleic acid sequences SEQ ID Nos:1-181.

Internal Calibration Standards For Electrophoretic Analyses

US Patent:
7593819, Sep 22, 2009
Filed:
Jul 11, 2002
Appl. No.:
10/193776
Inventors:
Timothy Hunkapiller - Mercer Island WA, US
Cheryl Heiner - La Honda CA, US
Curtis Gehman - Pasadena CA, US
James Labrenz - San Francisco CA, US
Shiaw-Min Chen - San Jose CA, US
Assignee:
Applied Biosystems, LLC - Carlsbad CA
International Classification:
G01N 33/50
C12Q 1/68
US Classification:
702 20, 435 6
Abstract:
The present teachings relate, among other things, to polynucleotide sequencing, fragment analysis and sample/lane tracking, and to polynucleotide sequencers and analyzers that employ optical detection techniques. Embodiments of the present teachings are described which include, for example, the addition of a calibration standard to a sequencing reaction. Information such as peak spacing and peak shape can he extracted from the standard.

Error-Free Amplification Of Dna For Clonal Sequencing

US Patent:
8003330, Aug 23, 2011
Filed:
Sep 26, 2008
Appl. No.:
12/286119
Inventors:
Cheryl Heiner - San Mateo CA, US
Stephen Turner - Menlo Park CA, US
Kevin Travers - Santa Clara CA, US
Assignee:
Pacific Biosciences of California, Inc. - Menlo Park CA
International Classification:
C12Q 1/68
C12P 19/34
US Classification:
435 612, 435 911, 435 912
Abstract:
Provided are methods of producing low copy number circularized nucleic acid variants that can be distributed to reaction volumes. The methods include providing a template nucleic acid; producing a population of clonal nucleic acids from the template nucleic acid; generating a set of partially overlapping nucleic acid fragments from the population of clonal nucleic acids; circularizing the partially overlapping nucleic acid fragments to produce circularized nucleic acid variants; and aliquotting the circularized nucleic acid variants into reaction volumes. Related compositions of nucleic acid templates are also provided.

Compositions And Methods For Nucleic Acid Sequencing

US Patent:
8153375, Apr 10, 2012
Filed:
Mar 27, 2009
Appl. No.:
12/413258
Inventors:
Kevin Travers - Santa Clara CA, US
Geoff Otto - San Carlos CA, US
Stephen Turner - Menlo Park CA, US
Cheryl Heiner - San Mateo CA, US
Congcong Ma - Foster City CA, US
Assignee:
Pacific Biosciences of California, Inc. - Menlo Park CA
International Classification:
C12Q 1/68
C12P 19/34
C07H 21/02
C07H 21/04
C07H 21/00
US Classification:
435 612, 435 61, 435 611, 435 911, 435 912, 536 231, 536 243, 536 2433, 536 253
Abstract:
Compositions and methods for nucleic acid sequencing include template constructs that comprise double stranded portions in a partially or completely contiguous constructs, to provide for redundant sequence determination through one or both of sequencing sense and antisense strands, and iteratively sequencing the entire construct multiple times. Additional sequence components are also optionally included within such template constructs. Methods are also provided for the use and preparation of these constructs as well as sequencing compositions for their application.

Methods And Compositions For Nucleic Acid Sample Preparation

US Patent:
8236499, Aug 7, 2012
Filed:
Mar 27, 2009
Appl. No.:
12/383855
Inventors:
Pranav Patel - Fremont CA, US
Keith Bjornson - Newark CA, US
Kevin Travers - Santa Clara CA, US
Cheryl Heiner - San Mateo CA, US
Assignee:
Pacific Biosciences of California, Inc. - Menlo Park CA
International Classification:
C12Q 1/68
C12P 19/34
C07H 21/02
C07H 21/04
C07H 21/00
US Classification:
435 61, 435 611, 435 911, 435 9152, 536 231, 536 243, 536 2433, 536 253
Abstract:
Provided are methods and compositions for the production of linear single-stranded nucleic acids, which can be used as templates in high-throughput sequencing systems. Also provided are methods and compositions for the production of closed single-stranded nucleic acid loops, which can be used as templates in high-throughput sequencing systems.

Internal Calibration Standards For Electrophoretic Analyses

US Patent:
8268558, Sep 18, 2012
Filed:
Sep 17, 2009
Appl. No.:
12/562070
Inventors:
Timothy Hunkapiller - Mercer Island WA, US
Cheryl Heiner - La Honda CA, US
Curtis Gehman - San Carlos CA, US
James Labrenz - San Francisco CA, US
Shiaw-Min Chen - San Jose CA, US
Assignee:
Applied Biosystems, LLC - Carlsbad CA
International Classification:
C12Q 1/68
C12P 19/34
C07H 21/02
C07H 21/04
US Classification:
435 61, 435 912, 536 231, 536 243
Abstract:
The present teachings relate, among other things, to polynucleotide sequencing, fragment analysis and sample/lane tracking, and to polynucleotide sequencers and analyzers that employ optical detection techniques. Embodiments of the present teachings are described which include, for example, the addition of a calibration standard to a sequencing reaction. Information such as peak spacing and peak shape can be extracted from the standard.

Diagnostic Sequencing With Small Nucleic Acid Circles

US Patent:
8309330, Nov 13, 2012
Filed:
Feb 1, 2011
Appl. No.:
13/019220
Inventors:
Kevin Travers - Menlo Park CA, US
Geoff Otto - Brookline MA, US
Stephen Turner - Menlo Park CA, US
Cheryl Heiner - San Mateo CA, US
Congcong Ma - Foster City CA, US
Assignee:
Pacific Biosciences of California, Inc. - Menlo Park CA
International Classification:
C12Q 1/68
C12P 19/34
C07H 21/02
C07H 21/04
C07H 21/00
US Classification:
435 912, 435 61, 435 611, 435 612, 435 911, 435 9151, 536 231, 536 243, 536 2433, 536 253
Abstract:
Methods, substrates, and systems for diagnostic sequencing are provided. Small circles of nucleic acids from about 10 bases to about 200 bases can be sequenced, for example using template dependent sequencing by synthesis. The use of small circles of nucleic acids allows for repeated sequencing of the same portions of the nucleic acid, providing for higher accuracy sequence determinations.

Compositions And Methods For Nucleic Acid Sequencing

US Patent:
8455193, Jun 4, 2013
Filed:
Feb 23, 2012
Appl. No.:
13/403789
Inventors:
Kevin Travers - Menlo Park CA, US
Geoff Otto - Brookline MA, US
Stephen Turner - Menlo Park CA, US
Cheryl Heiner - San Mateo CA, US
Congcong Ma - Foster City CA, US
Assignee:
Pacific Biosciences of California, Inc. - Menlo Park, CA
International Classification:
C12Q 1/68
C12P 19/34
C07H 21/02
C07H 21/04
C07H 21/00
US Classification:
435 61, 435 611, 435 612, 435 911, 435 912, 536 231, 536 243, 536 2433, 536 253
Abstract:
Compositions and methods for nucleic acid sequencing include template constructs that comprise double stranded portions in a partially or completely contiguous constructs, to provide for redundant sequence determination through one or both of sequencing sense and antisense strands, and iteratively sequencing the entire construct multiple times. Additional sequence components are also optionally included within such template constructs. Methods are also provided for the use and preparation of these constructs as well as sequencing compositions for their application.

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