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Christopher L Etienne, 52Fitchburg, WI

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Oregon, WI   

Madison, WI   

Woodbury, MN   

Basking Ridge, NJ   

Cranford, NJ   

Montclair, NJ   

Dane, WI   

Union, NJ   

Green Bay, WI   

2794 Sunflower Dr, Fitchburg, WI 53711    608-4411932   

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Christopher L Etienne

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Position: Professional/Technical

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Biotechnology

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Christopher Etienne Photo 37

Senior Research Scientist - Organic Chemistry

Location:
Madison, Wisconsin Area
Industry:
Biotechnology

Publications & IP owners

Us Patents

Modified Nucleotides

US Patent:
2011026, Oct 27, 2011
Filed:
Apr 20, 2011
Appl. No.:
13/090729
Inventors:
Kay Opperman - Rockton IL, US
Barbara J. Kaboord - Oregon WI, US
Jean-Samuel Schultz - Rockford IL, US
Christopher L. Etienne - Fitchburg WI, US
Greg Hermanson - Loves Park IL, US
Assignee:
PIERCE BIOTECHNOLOGY, INC. - Rockford IL
International Classification:
C12Q 1/68
C07H 19/10
G01N 33/50
C12P 19/34
US Classification:
435 611, 435 913, 536 263, 436 94
Abstract:
Modified nucleotides, and methods to modify nucleotides with a moiety or label, such as biotin, that permits their detection and results in a modified nucleotide, and methods of use of the modified nucleotide in quantitative and qualitative assays.

Modified Nucleotides Methods And Kits

US Patent:
2012025, Oct 4, 2012
Filed:
May 29, 2012
Appl. No.:
13/482927
Inventors:
Christopher L. Etienne - Fitchburg WI, US
Kay K. Opperman - Rockton IL, US
Barbara J. Kaboord - Oregon WI, US
Scott Meier - Rockford IL, US
Jean-Samuel Schultz - Rockford IL, US
Assignee:
Pierce Biotechnology, Inc. - Rockford IL
International Classification:
C07H 19/10
C12Q 1/68
C40B 30/04
G01N 33/566
C07K 17/10
C07H 21/02
US Classification:
506 9, 536 263, 530409, 536 231, 436501, 435 61, 435 611
Abstract:
Modified nucleotides, and methods to modify nucleotides with a moiety or label, such as biotin, that permits their detection and results in a modified nucleotide, and methods of use of the modified nucleotide in quantitative and qualitative assays.

Methods And Reagents For Biomolecule Labeling, Enrichment And Gentle Elution

US Patent:
2013030, Nov 21, 2013
Filed:
Mar 11, 2013
Appl. No.:
13/794248
Inventors:
Ryan Daniel Bomgarden - Winnebago IL, US
Christopher Laurence Etienne - Fitchburg WI, US
Eric Leigh Hommema - Roscoe IL, US
Assignee:
Pierce Biotechnology, Inc. - Rockford IL
International Classification:
G01N 33/68
G01N 33/58
US Classification:
435 72, 506 9, 436501
Abstract:
Methods and sets of non-biological reagents (elution reagents, tag isomers, tag reactive groups, crosslinkers) for single or multiplexed capture and gentle elution of biomolecules. Examples are provided using amine- and cysteine-reactive reagents for enrichment of proteins, peptides, and rare peptide modifications.

Quantitative Peptide Or Protein Assay

US Patent:
2021000, Jan 7, 2021
Filed:
Jul 23, 2020
Appl. No.:
16/936848
Inventors:
- Rockford IL, US
Christopher L. Etienne - Oregon WI, US
Sijian Hou - Rockford IL, US
Erum Raja - Rockford IL, US
Ramesh Ganapathy - Loves Park IL, US
Assignee:
Pierce Biotechnology, Inc. - Rockford IL
International Classification:
G01N 33/68
Abstract:
Peptide and/or protein quantitation methods, kits, and compositions, particularly useful for mass spectrometry, are provided herein based on a bathocuproine-based composition complex such as bathocuproinedisulfonic acid disodium salt hydrate complex. The methods are one-step rapid absorbance methods using small sample volumes. They produce a robust signal with high signal to background ratio and accurately quantitate even complex peptide mixtures with low variability and high sensitivity.

Quantitative Peptide Or Protein Assay

US Patent:
2019019, Jun 27, 2019
Filed:
Mar 12, 2019
Appl. No.:
16/299667
Inventors:
- Rockford IL, US
Christopher L. Etienne - Oregon WI, US
Sijian Hou - Rockford IL, US
Erum Raja - Rockford IL, US
Ramesh Ganapathy - Loves Park IL, US
Assignee:
Pierce Biotechnology, Inc. - Rockford IL
International Classification:
G01N 33/68
Abstract:
Peptide and/or protein quantitation methods, kits, and compositions, particularly useful for mass spectrometry, are provided herein based on a bathocuproine-based composition complex such as bathocuproinedisulfonic acid disodium salt hydrate complex. The methods are one-step rapid absorbance methods using small sample volumes. They produce a robust signal with high signal to background ratio and accurately quantitate even complex peptide mixtures with low variability and high sensitivity.

Methods Of Mass Spectrometry Quantitation Using Cleavable Isobaric Tags And Neutral Loss Fragmentation

US Patent:
2019001, Jan 10, 2019
Filed:
Jul 6, 2018
Appl. No.:
16/028932
Inventors:
- San Jose CA, US
Graeme McALISTER - San Jose CA, US
Christopher L. Etienne - Oregon WI, US
International Classification:
H01J 49/00
Abstract:
Isobaric mass spectrometry tags (e.g., TMT) are susceptible to ratio compression, which arises from the co-isolation and co-fragmentation of interfering species that also contribute to the final reporter ion ratios. Additional stages of ion activation/transformation (e.g., MSn and PTR) have been shown to decrease ratio compression. Embodiments of the present invention include a mass spectrometry cleavable moiety on the isobaric mass tags. The cleavable moiety allows for a predictable mass loss, and results in an improved tag reporter ion purity.

Methods And Reagents For Biomolecule Labeling, Enrichment And Gentle Elution

US Patent:
2018005, Feb 22, 2018
Filed:
Oct 31, 2017
Appl. No.:
15/798621
Inventors:
- Carlsbad CA, US
Ryan BOMGARDEN - Rockford IL, US
Christopher ETIENNE - Oregon WI, US
Eric HOMMEMA - Roscoe IL, US
International Classification:
G01N 33/68
G01N 33/58
Abstract:
Methods and sets of non-biological reagents (elution reagents, tag isomers, tag reactive groups, crosslinkers) for single or multiplexed capture and gentle elution of biomolecules. Examples are provided using amine- and cysteine-reactive reagents for enrichment of proteins, peptides, and rare peptide modifications.

Quantitative Peptide Or Protein Assay

US Patent:
2017034, Nov 30, 2017
Filed:
Aug 11, 2017
Appl. No.:
15/674831
Inventors:
- Rockford IL, US
Christopher L. Etienne - Oregon WI, US
Sijian Hou - Rockford IL, US
Erum Raja - Rockford IL, US
Ramesh Ganapathy - Loves Park IL, US
Assignee:
Pierce Biotechnology, Inc. - Rockford IL
International Classification:
G01N 33/68
Abstract:
Peptide and/or protein quantitation methods, kits, and compositions, particularly useful for mass spectrometry, are provided herein based on a bathocuproine-based composition complex such as bathocuproinedisulfonic acid disodium salt hydrate complex. The methods are one-step rapid absorbance methods using small sample volumes. They produce a robust signal with high signal to background ratio and accurately quantitate even complex peptide mixtures with low variability and high sensitivity.

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