Christopher J Markworth, 533901 Viewmont Ct, Bellingham, WA 98229
Christopher Markworth Phones & Addresses
3901 Viewmont Ct, Bellingham, WA 98229
5915 Tahoe Dr, Durham, NC 27713 919-3615397
1104 Montana Ave, Bozeman, MT 59715 406-5860334
Chapel Hill, NC
Wilmington, NC
Bloomington, IN
Wake Forest, NC
4017 Springland Ln, Bellingham, WA 98226
Work
Position:
Professional/Technical
Mentions for Christopher J Markworth
Publications & IP owners
Us Patents
Sulfonamide Derivatives
US Patent:
8153814, Apr 10, 2012
Filed:
Jan 12, 2010
Appl. No.:
12/685913
Inventors:
Serge Beaudoin - Durham NC, US
Michael Christopher Laufersweiler - Durham NC, US
Christopher John Markworth - Durham NC, US
Brian Edward Marron - Durham NC, US
David Simon Millan - Sandwich, GB
David James Rawson - Sandwich, GB
Steven Michael Reister - Durham NC, US
Kosuke Sasaki - Sandwich, GB
Robert Ian Storer - Sandwich, GB
Paul Anthony Stupple - Sandwich, GB
Nigel Alan Swain - Sandwich, GB
Christopher William West - Durham NC, US
Shulan Zhou - Durham NC, US
Michael Christopher Laufersweiler - Durham NC, US
Christopher John Markworth - Durham NC, US
Brian Edward Marron - Durham NC, US
David Simon Millan - Sandwich, GB
David James Rawson - Sandwich, GB
Steven Michael Reister - Durham NC, US
Kosuke Sasaki - Sandwich, GB
Robert Ian Storer - Sandwich, GB
Paul Anthony Stupple - Sandwich, GB
Nigel Alan Swain - Sandwich, GB
Christopher William West - Durham NC, US
Shulan Zhou - Durham NC, US
Assignee:
Pfizer Limited - Sandwich
Icagen, Inc. - Durham NC
Icagen, Inc. - Durham NC
International Classification:
C07D 277/00
A61K 31/425
A61K 31/425
US Classification:
548190, 514371
Abstract:
The present invention relates to compounds of the formula.
Heterocyclic Sulfonamides As Inhibitors Of Ion Channels
US Patent:
8357711, Jan 22, 2013
Filed:
Mar 20, 2008
Appl. No.:
12/052593
Inventors:
Brian Edward Marron - Durham NC, US
Paul Christopher Fritch - Cary NC, US
Christopher John Markworth - Durham NC, US
Andrew Thomas Maynard - Durham NC, US
Nigel Alan Swain - Sandwich, GB
Paul Christopher Fritch - Cary NC, US
Christopher John Markworth - Durham NC, US
Andrew Thomas Maynard - Durham NC, US
Nigel Alan Swain - Sandwich, GB
Assignee:
Pfizer Limited - Sandwich
Icagen, Inc. - Durham NC
Icagen, Inc. - Durham NC
International Classification:
A61K 31/427
US Classification:
514370, 548190
Abstract:
The invention is directed to compounds of the formula.
Sulfonamide Derivatives
US Patent:
8541588, Sep 24, 2013
Filed:
Feb 20, 2012
Appl. No.:
13/400356
Inventors:
Serge Beaudoin - Durham NC, US
Michael Christopher Laufersweiler - Durham NC, US
Christopher John Markworth - Durham NC, US
Brian Edward Marron - Durham NC, US
David Simon Millan - Sandwich, GB
David James Rawson - Sandwich, GB
Steven Michael Reister - Durham NC, US
Kosuke Sasaki - Sandwich, GB
Robert Ian Storer - Sandwich, GB
Paul Anthony Stupple - Sandwich, GB
Nigel Alan Swain - Sandwich, GB
Christopher William West - Durham NC, US
Shulan Zhou - Durham NC, US
Michael Christopher Laufersweiler - Durham NC, US
Christopher John Markworth - Durham NC, US
Brian Edward Marron - Durham NC, US
David Simon Millan - Sandwich, GB
David James Rawson - Sandwich, GB
Steven Michael Reister - Durham NC, US
Kosuke Sasaki - Sandwich, GB
Robert Ian Storer - Sandwich, GB
Paul Anthony Stupple - Sandwich, GB
Nigel Alan Swain - Sandwich, GB
Christopher William West - Durham NC, US
Shulan Zhou - Durham NC, US
Assignee:
Pfizer Limited - Sandwich
Icagen, Inc. - Durham NC
Icagen, Inc. - Durham NC
International Classification:
C07D 277/00
C07D 211/72
A61K 31/44
C07D 211/72
A61K 31/44
US Classification:
546290, 548190, 514345
Abstract:
The present invention relates to compounds of the formula.
Compounds And Methods Of Use Thereof
US Patent:
2008026, Oct 30, 2008
Filed:
Oct 27, 2005
Appl. No.:
11/718284
Inventors:
Tatyana Dyakonov - Durham NC, US
Michael L. Jones - Chapel Hill NC, US
Christopher J. Markworth - Durham NC, US
Jessymol Mathew - Raleigh NC, US
Frank J. Schoenen - Lawrence KS, US
David S. Van Vliet - Chapel Hill NC, US
David Middlemiss - Bishop's Stortford, GB
Michael L. Jones - Chapel Hill NC, US
Christopher J. Markworth - Durham NC, US
Jessymol Mathew - Raleigh NC, US
Frank J. Schoenen - Lawrence KS, US
David S. Van Vliet - Chapel Hill NC, US
David Middlemiss - Bishop's Stortford, GB
International Classification:
C07D 279/16
A61K 31/5415
C07D 265/36
A61P 1/00
A61P 17/06
A61P 11/00
A61P 3/10
A61P 9/12
A61P 15/10
A61P 35/00
A61P 25/28
A61P 11/06
A61P 19/02
A61P 29/00
A61K 31/536
A61K 31/5415
C07D 265/36
A61P 1/00
A61P 17/06
A61P 11/00
A61P 3/10
A61P 9/12
A61P 15/10
A61P 35/00
A61P 25/28
A61P 11/06
A61P 19/02
A61P 29/00
A61K 31/536
US Classification:
5142242, 544 52, 544105, 5142305
Abstract:
Benzolactam boronic acid compounds and pharmaceutical formulations are described along with methods of use thereof for inhibiting inflammatory cytokines such as tumor necrosis factor alpha (TNF-α) in a subject in need thereof.
Compounds And Methods Of Use Thereof
US Patent:
2008031, Dec 25, 2008
Filed:
Oct 27, 2005
Appl. No.:
11/718286
Inventors:
John R. Didsbury - Raleigh NC, US
Tatyana A. Dyakonov - Durham NC, US
Simon N. Haydar - Newton PA, US
Michael L. Jones - Chapel Hill NC, US
Francine F. Li - Chester Springs PA, US
Christopher J. Markworth - Durham NC, US
Jessymol Mathew - Raleigh NC, US
Frank J. Schoenen - Lawrence KS, US
Jan J. Scicinski - Sunnyvale CA, US
David Middlemiss - Bishop's Stortford, GB
Tatyana A. Dyakonov - Durham NC, US
Simon N. Haydar - Newton PA, US
Michael L. Jones - Chapel Hill NC, US
Francine F. Li - Chester Springs PA, US
Christopher J. Markworth - Durham NC, US
Jessymol Mathew - Raleigh NC, US
Frank J. Schoenen - Lawrence KS, US
Jan J. Scicinski - Sunnyvale CA, US
David Middlemiss - Bishop's Stortford, GB
Assignee:
NUADA, LLC - Durham NC
International Classification:
A61K 31/404
C07D 209/04
A61P 1/00
A61P 19/02
A61P 17/06
A61P 25/28
A61P 9/00
A61P 3/10
A61P 35/00
A61P 9/12
A61P 15/10
C07D 209/04
A61P 1/00
A61P 19/02
A61P 17/06
A61P 25/28
A61P 9/00
A61P 3/10
A61P 35/00
A61P 9/12
A61P 15/10
US Classification:
514415, 548491
Abstract:
Indole boronic acid compounds, and analogs thereof, and pharmaceutical formulations are described, along with methods of use thereof for inhibiting inflammatory cytokines such as tumor necrosis factor alpha (TNF-α) in a subject in need thereof.
Compounds And Methods Of Use Thereof
US Patent:
2009000, Jan 1, 2009
Filed:
Oct 27, 2005
Appl. No.:
11/718277
Inventors:
James F. Burns - Raleigh NC, US
Leonardo A. Cabana - Cary NC, US
Glenn C. Collupy - Durham NC, US
John R. Didsbury - Raleigh NC, US
Tatyana A. Dyakonov - Durham NC, US
Simon N. Haydar - Newton PA, US
Michael L. Jones - Chapel Hill NC, US
Francine F. Li - Chester Springs PA, US
Christopher J. Markworth - Durham NC, US
Jessymol Mathew - Raleigh NC, US
Frank J. Schoenen - Lawrence KS, US
David S. Van Vliet - Chapel Hill NC, US
David Middlemiss - Bishop's Stortford, GB
Leonardo A. Cabana - Cary NC, US
Glenn C. Collupy - Durham NC, US
John R. Didsbury - Raleigh NC, US
Tatyana A. Dyakonov - Durham NC, US
Simon N. Haydar - Newton PA, US
Michael L. Jones - Chapel Hill NC, US
Francine F. Li - Chester Springs PA, US
Christopher J. Markworth - Durham NC, US
Jessymol Mathew - Raleigh NC, US
Frank J. Schoenen - Lawrence KS, US
David S. Van Vliet - Chapel Hill NC, US
David Middlemiss - Bishop's Stortford, GB
Assignee:
NKUADA, LLC - Durham NC
International Classification:
A61K 31/4184
A61K 31/381
A61P 43/00
A61P 29/00
A61P 19/02
A61P 17/06
A61P 19/08
A61P 11/06
A61K 31/381
A61P 43/00
A61P 29/00
A61P 19/02
A61P 17/06
A61P 19/08
A61P 11/06
US Classification:
514 64, 5483097, 514394, 5483101, 548181, 514365, 548110, 568 6, 5483044, 546 13
Abstract:
Imidazole and benzimidazole boronic acid compounds, analogs thereof, and pharmaceutical formulations are described, along with methods of use thereof for inhibiting inflammatory cytokines such as tumor necrosis factor alpha (TNF-α) in a subject in need thereof.
Sodium Channel Inhibitors
US Patent:
2009002, Jan 22, 2009
Filed:
Jul 14, 2008
Appl. No.:
12/173012
Inventors:
Alan Bradley Fulp - Willow Spring NC, US
Matthew Scott Johnson - Durham NC, US
Christopher John Markworth - Durham NC, US
Brian Edward Marron - Durham NC, US
Darrick Conway Seconi - Cary NC, US
Christopher William West - Cary NC, US
Xiaodong Wang - Chapel Hill NC, US
Shulan Zhou - Chapel Hill NC, US
Matthew Scott Johnson - Durham NC, US
Christopher John Markworth - Durham NC, US
Brian Edward Marron - Durham NC, US
Darrick Conway Seconi - Cary NC, US
Christopher William West - Cary NC, US
Xiaodong Wang - Chapel Hill NC, US
Shulan Zhou - Chapel Hill NC, US
Assignee:
Icagen - Durham NC
International Classification:
A61K 31/502
C07D 409/12
A61K 31/427
A61K 31/4439
C07D 409/14
C07D 409/12
A61K 31/427
A61K 31/4439
C07D 409/14
US Classification:
514248, 544237, 548197, 514370, 514341, 5462707
Abstract:
Compounds, compositions and methods are provided which are useful in the treatment of diseases through the inhibition of sodium ion flux through voltage-gated sodium channels. More particularly, the invention provides substituted sulfonamides, compositions comprising these compounds, as well as methods of using these compounds or compositions in the treatment of central or peripheral nervous system disorders, particularly pain and chronic pain by blocking sodium channels associated with the onset or recurrence of the indicated conditions. The compounds, compositions and methods of the present invention are of particular use for treating neuropathic or inflammatory pain by the inhibition of ion flux through a voltage-gated sodium channel.
Indole, Benzimidazole, And Benzolactam Boronic Acid Compounds, Analogs Thereof And Methods Of Use Thereof
US Patent:
2009026, Oct 22, 2009
Filed:
Nov 10, 2008
Appl. No.:
12/268237
Inventors:
John R. Didsbury - Raleigh NC, US
Tatyana Dyakonov - Greensboro NC, US
Simon N. Haydar - Newton PA, US
Michael L. Jones - Chapel Hill NC, US
Francine F. Li - Chester Springs PA, US
Christopher J. Markworth - Durham NC, US
Jessy Matthew - Raleigh NC, US
Frank J. Schoenen - Laurence KS, US
Jan J. Scicinski - Mountain View CA, US
David Middlemiss - Bishop's Stortford, GB
James F. Burns - Glen Ridge NJ, US
Leonard A. Cabana - Durham NC, US
Glenn C. Collupy - Durham NC, US
David N. Vanvliet - Chapel Hill NC, US
Tatyana Dyakonov - Greensboro NC, US
Simon N. Haydar - Newton PA, US
Michael L. Jones - Chapel Hill NC, US
Francine F. Li - Chester Springs PA, US
Christopher J. Markworth - Durham NC, US
Jessy Matthew - Raleigh NC, US
Frank J. Schoenen - Laurence KS, US
Jan J. Scicinski - Mountain View CA, US
David Middlemiss - Bishop's Stortford, GB
James F. Burns - Glen Ridge NJ, US
Leonard A. Cabana - Durham NC, US
Glenn C. Collupy - Durham NC, US
David N. Vanvliet - Chapel Hill NC, US
Assignee:
Nuada, Inc. - Durham NC
International Classification:
A61K 31/69
A61P 1/00
A61P 19/02
A61P 17/06
A61P 11/06
A61P 11/00
A61P 17/00
A61P 37/08
A61P 1/00
A61P 19/02
A61P 17/06
A61P 11/06
A61P 11/00
A61P 17/00
A61P 37/08
US Classification:
514 64
Abstract:
Benzimidazole, indole and benzolactam boronic acid compounds, analogs thereof, and pharmaceutical formulations are described, along with methods of use thereof for inhibiting inflammatory cytokines such as tumor necrosis factor alpha (TNF-α) in a subject in need thereof.
NOTICE: You may not use BackgroundCheck or the information it provides to make decisions about employment, credit, housing or any other purpose that would require Fair Credit Reporting Act (FCRA) compliance. BackgroundCheck is not a Consumer Reporting Agency (CRA) as defined by the FCRA and does not provide consumer reports.