Inventors:
Cortney E. Henderson - Loveland OH, US
Taylor W. Aronhalt - Loveland OH, US
Chunlin Yang - Belle Mead NJ, US
Charles J. Scheib - Loveland OH, US
Venkataramanan Mandakolathur Vasudevan - Mahim (W), IN
Mark D. Timmer - Jersey City NJ, US
Richard W. Timm - Cincinnati OH, US
Tamara Widenhouse - Clarksville OH, US
Steven G. Hall - Cincinnati OH, US
Assignee:
Ethicon Endo-Surgery, Inc. - Cincinnati OH
International Classification:
A61K 9/00
A61K 38/39
A61K 38/48
A61K 38/36
A61K 38/38
A61K 31/715
A61K 31/718
A61K 31/717
A61K 31/722
A61K 31/78
A61K 31/785
A61K 33/06
A61K 33/26
A61K 33/30
A61K 35/32
A61K 31/196
A61K 31/616
A61K 31/192
A61K 31/573
A61P 17/02
A61M 5/00
US Classification:
60428804, 604 9301, 424400, 514 172, 424 9464, 514 136, 514 93, 514 152, 514 54, 514 60, 514 57, 514 55, 424 7831, 424 7837, 424698, 424682, 424647, 424642, 424685, 424549, 514567, 514165, 514569, 514171
Abstract:
A tissue thickness compensator may generally comprise a first layer comprising a first medicament, a second layer comprising a second medicament, and a third layer comprising a third medicament. The tissue thickness compensator may comprise a first layer comprising a first medicament, a second layer comprising a second medicament, and a reservoir comprising a third medicament disposed within the reservoir. The medicaments may be independently selected from a haemostatic agent, an anti-inflammatory agent, an antibiotic agent, anti-microbial agent, an anti-adhesion agent, an anti-coagulant agent, a pharmaceutically active agent, a matrix metalloproteinase inhibitor, and combinations thereof. Articles of manufacture comprising the tissue thickness compensator and methods of making and using the tissue thickness compensator are also described.