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Dan Zhou, 6864 Blossomcrest Rd, Lexington, MA 02421

Known as:
Dan Huang Dan Vhou Zhou Din
Related to:
Lily Huang 39

Dan Zhou Phones & Addresses

64 Blossomcrest Rd, Lexington, MA 02421    781-8635874   

35 Brandon St, Lexington, MA 02420    781-8635874   

Cambridge, MA   

Malden, MA   

Hanover, NH   

64 Blossomcrest Rd, Lexington, MA 02421   

Work

Position: Professional/Technical

Education

Degree: Graduate or professional degree
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Mentions for Dan Zhou

Career records & work history

License Records

Dan Zhou

Licenses:
License #: CC-0004571 - Active
Category: Accountancy
Issued Date: Feb 19, 2004
Type: C.P.A. Certificate

Dan Zhou resumes & CV records

Resumes

Dan Zhou Photo 40

Nanjing Medical University

Location:
Lexington, MA
Industry:
Pharmaceuticals
Work:
Synta Pharmaceuticals 2003 - 2015
Director and Senior Director, Toxicology Shionogi Bioresearch Corp 1998 - 2002
Senior Scientist I and Ii 1998 - 2002
Nanjing Medical University
Education:
Shanghai Medical College of Fudan University
Harvard Medical School - Massachusetts General Hospital
Nanjing Medical University
Doctor of Medicine, Doctorates, Medicine Cambridge College
Masters, Business Administration, Management, Business Administration and Management
Skills:
Drug Discovery, Pharmaceutical Industry, Biotechnology, Oncology, Clinical Development, Drug Development, Biomarkers, Dmpk, Glp, Safety Assessment, Ind Toxicology Study Design, Ind Submission, Lead Optimization, Toxicology Team Leader, Predictive Toxicology, Risk Management, Profiling Target Organ Toxicity, Histopathology, In Vitro Cytotoxicity Assays, Animal Models, In Vivo Assay Establishment, Cardiac Toxicity Identification, Immunotoxicity Testing, Neurotoxicity Screening, Hepatotoxicity Evaluation, Ocular Toxicity Testing, Nephrotoxicity Testing, Myelosuppression Assessment, Gi Toxicity Testing, Cross Functional Teamwork
Languages:
English
Mandarin
Dan Zhou Photo 41

Dan Zhou

Publications & IP owners

Us Patents

Treatment For Cancers

US Patent:
7763658, Jul 27, 2010
Filed:
Jan 15, 2004
Appl. No.:
10/758589
Inventors:
Keizo Koya - Chestnut Hill MA, US
Lijun Sun - Harvard MA, US
Yaming Wu - Lexington MA, US
Timothy Korbut - Brighton MA, US
Dan Zhou - Lexington MA, US
Zhenjian Du - Northborough MA, US
Shoujun Chen - Bedford MA, US
Noriaki Tatsuta - Lexington MA, US
Guiqing Liang - Concord MA, US
Mitsunori Ono - Lexington MA, US
Assignee:
Synta Pharmaceuticals Corp. - Lexington MA
International Classification:
A61K 31/16
US Classification:
514599, 514614
Abstract:
One embodiment of the present invention is a method of treating a subject with a multi-drug resistant cancer. The method comprises administering to the subject an effective amount of a compound represented by Structural Formula (I):.

Triazole Compounds That Modulate Hsp90 Activity

US Patent:
8053456, Nov 8, 2011
Filed:
May 25, 2007
Appl. No.:
11/807327
Inventors:
Lijun Sun - Harvard MA, US
Weiwen Ying - Ayer MA, US
Junghyun Chae - Youngdengpo-gu, KR
Teresa Przewloka - Tewksbury MA, US
Shijie Zhang - Nashua NH, US
Dinesh U. Chimmanamada - Waltham MA, US
Kevin Foley - Waltham MA, US
Zhenjian Du - Northborough MA, US
Hao Li - Brookline MA, US
David James - Cambridge MA, US
Howard P. Ng - Belmont MA, US
Zachary Demko - Somerville MA, US
Dan Zhou - Lexington MA, US
Shuzhen Qin - West Roxbury MA, US
Assignee:
Synta Pharmaceuticals Corp. - Lexington MA
International Classification:
A61K 31/4196
C07D 249/12
US Classification:
514384, 5482632
Abstract:
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.

Triazole Compounds That Modulate Hsp90 Activity

US Patent:
8183384, May 22, 2012
Filed:
May 25, 2007
Appl. No.:
11/807331
Inventors:
Dinesh U. Chimmanamada - Arlington MA, US
Weiwen Ying - Ayer MA, US
Teresa Przewloka - Tewksbury MA, US
Shijie Zhang - Nashua NH, US
Kevin Foley - Waltham MA, US
Zhenjian Du - Northborough MA, US
Dan Zhou - Lexington MA, US
Shuzhen Qin - West Roxbury MA, US
Assignee:
Synta Pharmaceuticals Corp. - Lexington MA
International Classification:
C07D 249/12
A61K 31/4196
US Classification:
5482632, 514384
Abstract:
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.

Triazole Compounds That Modulate Hsp90 Activity

US Patent:
8318790, Nov 27, 2012
Filed:
May 25, 2007
Appl. No.:
11/807201
Inventors:
Weiwen Ying - Ayer MA, US
David James - Cambridge MA, US
Shijie Zhang - Nashua NH, US
Junghyun Chae - Youngdengpo-gu, KR
Teresa Przewloka - Tewksbury MA, US
Howard P. Ng - Belmont MA, US
Hao Li - Brookline MA, US
Zachary Demko - Somerville MA, US
Dinesh U. Chimmanamada - Arlington MA, US
Chi-wan Lee - Grafton MA, US
Zhenjian Du - Northborough MA, US
Kevin Foley - Waltham MA, US
Minghu Song - Waltham MA, US
Lijun Sun - Harvard MA, US
Keizo Koya - Chestnut Hill MA, US
Dan Zhou - Lexington MA, US
Shuzhen Qin - West Roxbury MA, US
Assignee:
Synta Pharmaceuticals Corp. - Lexington MA
International Classification:
A61K 31/4196
A61P 35/00
C07D 249/12
US Classification:
514384, 5482646
Abstract:
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.

Triazole Compounds That Modulate Hsp90 Activity

US Patent:
8329736, Dec 11, 2012
Filed:
Apr 20, 2012
Appl. No.:
13/452200
Inventors:
Dinesh U. Chimmanamada - Arlington MA, US
Weiwen Ying - Ayer MA, US
Teresa Kowalczyk Przewloka - Tewksbury MA, US
Shijie Zhang - Nashua NH, US
Kevin Foley - Waltham MA, US
Zhenjian Du - Northborough MA, US
Dan Zhou - Lexington MA, US
Shuzhen Qin - West Roxbury MA, US
Assignee:
Synta Pharmaceuticals, Corp. - Lexington MA
International Classification:
A61K 31/4196
C07D 249/12
US Classification:
514384, 5482632
Abstract:
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.

Triazole Compounds That Modulate Hsp90 Activity

US Patent:
8415377, Apr 9, 2013
Filed:
Sep 9, 2011
Appl. No.:
13/229178
Inventors:
Lijun Sun - Harvard MA, US
Weiwen Ying - Ayer MA, US
Junghyun Chae - Youngdengpo-gu, KR
Teresa Przewloka - Tewksbury MA, US
Shijie Zhang - Nashua NH, US
Dinesh Chimmanamada - Waltham MA, US
Kevin Foley - Waltham MA, US
Zhenjian Du - Northborough MA, US
Hao Li - Brookline MA, US
David James - Cambridge MA, US
Howard Ng - Belmont MA, US
Zachary Demko - Somerville MA, US
Dan Zhou - Lexington MA, US
Shuzhen Qin - West Roxbury MA, US
Assignee:
Synta Pharmaceuticals Corp. - Lexington MA
International Classification:
C07D 401/14
C07D 403/04
A61K 31/4196
A61K 31/4709
US Classification:
514314, 514383, 5482664, 546167
Abstract:
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.

Triazinone And Diazinone Derivatives Useful As Hsp90 Inhibitors

US Patent:
8524712, Sep 3, 2013
Filed:
Mar 24, 2008
Appl. No.:
12/593147
Inventors:
Chi-Wan Lee - Grafton MA, US
Teresa Przewloka - Tewksbury MA, US
Weiwen Ying - Groton MA, US
Minghu Song - Waltham MA, US
Zhenjian Du - Northborough MA, US
Kevin Foley - Waltham MA, US
Dan Zhou - Lexington MA, US
Shuzhen Qin - West Roxbury MA, US
Assignee:
Synta Pharmaceuticals Corp. - Lexington MA
International Classification:
A61K 31/53
A61K 31/519
A61K 31/47
C07D 401/04
C07D 253/06
C07D 471/02
C07D 487/02
US Classification:
514242, 514256, 5142601, 5142651, 514314, 544182, 544278, 544280
Abstract:
The present invention relates to compounds according to formulae (IA) to (ID) and compositions that inhibit the activity of Hsp90. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a compound of the invention, or a composition comprising such a compound.

Dihydropyridine Compounds For Treating Or Preventing Metabolic Disorders

US Patent:
2005020, Sep 15, 2005
Filed:
Sep 10, 2004
Appl. No.:
10/939252
Inventors:
Mitsunori Ono - Lexington MA, US
Yumiko Wada - Billerica MA, US
Lijun Sun - Harvard MA, US
Shoujun Chen - Bedford MA, US
Teresa Przewloka - Tewksbury MA, US
Shijie Zhang - Nashua NH, US
Christopher Borella - Cambridge MA, US
Keizo Koya - Chestnut Hill MA, US
Kevin Foley - Cambridge MA, US
Zhi-Qiang Xia - Acton MA, US
Hao Li - Brookline MA, US
Dan Zhou - Lexington MA, US
International Classification:
C07D471/02
C07D491/02
C07D498/02
A61K031/4745
A61K031/4743
A61K031/4741
A61K031/47
US Classification:
514300000, 546178000, 546122000, 546115000, 546114000, 514311000, 514302000, 514301000
Abstract:
This invention relates to dihydropyridine compounds of formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof wherein A, R, R, R, R, R, R, R, R, R, R, R, and m are defined herein, and compositions comprising such compounds. The invention also relates to methods of preventing or treating metabolic disorders, such as diabetes mellitus, and conditions and complications associated with diabetes mellitus, comprising administering to a subject in need thereof a compound of formula (1) or a composition comprising such a compound. The invention further relates to kits comprising a compound of formula (I).

Possible Relatives

David Zhou  De W Zhou  Darren Zhou  Dj P Zhou  Dongguang S Zhou  Erxin Zhou  Fan Zhou  Dan Johnson  Dan W Stanaway  Dan L Johnston 

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