Daniel Francis Dwyer, 60Boston, MA

7766526, Aug 3, 2010

Sep 13, 2007

11/854976

Daniel Dwyer - Medinah IL, US
J. Boyd Hildebrant - Palatine IL, US
Jeff Graham - Winnetka IL, US

iSky Panel Systems, Inc. - Winnetka IL

F21V 7/04

362554, 345 84, 349 61

Disclosed is an illumination device. The device includes a light engine in an acoustic tile that introduces light into a plurality of optical fibers using an LED. In between the LED and the fiber ends, an LCD is used to modify the light introduced. To do this, the LCD is programmed to display petal-shaped sections which individually change in contrast to become more occluded and then more transparent. This creates an aesthetically pleasing effect resembling stars.

8366371, Feb 5, 2013

Nov 30, 2007

11/948131

Leonard J. Maniscalco - Oak Brook IL, US
Paul R. Egger - Franklin Park IL, US
Daniel J. Dwyer - Glen Ellyn IL, US

Sacket Material Handling Systems, Inc. - Bensenville IL

B65G 1/00

414279, 41422207, 104 34

A battery movement, storage, and charging system for large size batteries used in lift trucks includes spaced, parallel storage racks, each of which have multiple storage and charging bays. A battery transport tower is positioned in an aisle between the storage racks and is moveable horizontally between the two rows of racks. The tower includes an extendable fork lift mounted which may rotate around the axis of the tower as well as move vertically upwardly or downwardly on the tower. A battery exchanger loads a discharged battery from a lift truck, places it on a pallet and then transfers the pallet and battery to a transfer bay in a storage rack where the tower forklift moves a pallet and battery to a selected charging bay.

2007013, Jun 14, 2007

Nov 14, 2003

10/535128

James Collins - Newton MA, US
Farren Isaacs - Brookline MA, US
Charles Cantor - Del Mar CA, US
Daniel Dwyer - Brookline MA, US

TRUSTEES OF BOSTON UNIVERSITY - Boston MA

A01K 67/027
C07H 21/04
C12N 15/09
C12N 5/06

800014000, 435325000, 435455000, 536023200

The present invention provides nucleic acid molecules, DNA constructs, plasmids, and methods for post-transcriptional regulation of gene expression using RNA molecules to both repress and activate translation of an open reading frame. Repression of gene expression is achieved through the presence of a regulatory nucleic acid element (the cis-repressive RNA or crRNA) within the 5′ untranslated region (5′ UTR) of an mRNA molecule. The nucleic acid element forms a hairpin (stem/loop) structure through complementary base pairing. The hairpin blocks access to the mRNA transcript by the ribosome, thereby preventing translation. In particular, in embodiments of the invention designed to operate in prokaryotic cells, the stem of the hairpin secondary structure sequesters the ribosome binding site (RBS). In embodiments of the invention designed to operate in eukaryotic cells, the stem of the hairpin is positioned upstream of the start codon, anywhere within the 5′ UTR of an mRNA. A small RNA (trans-activating RNA, or taRNA), expressed in trans, interacts with the crRNA and alters the hairpin structure. This alteration allows the ribosome to gain access to the region of the transcript upstream of the start codon, thereby activating transcription from its previously repressed state.

2010002, Feb 4, 2010

Feb 13, 2007

12/279243

Guillaume Cottarel - Lexington MA, US
Jamey Wierzbowski - Stoneham MA, US
Kollol Pal - Needham MA, US
Michael Kohanski - Allston MA, US
Daniel Dwyer - Watertown MA, US
James Collins - Newton MA, US
Michael Almstetter - Grasbrunn, DE
Michael Thormann - Martinsried, DE
Andreas Treml - Bodenmais, DE

TRUSTEES OF BOSTON UNIVERSITY - Boston MA
PURETECH VENTURES - Boston MA

A61K 31/65
A61K 31/352
A61K 31/382
A61K 31/47
A61P 31/04

514154, 514456, 514432, 514311

The present invention is directed to the use of RecA inhibitors as antibiotic agents, and provides RecA inhibitors useful in treating infections. Also provided are various compositions and methods associated with RecA inhibition.

5331126, Jul 19, 1994

Jun 15, 1993

8/076041

Daniel Dwyer - Norton MA
Daniel Morin - North Providence RI
Massimo Mazzola - Napoli, IT
Karl R. Abrahamson - Easton MA

Texas Instruments Incorporated - Dallas TX

H01H 3534

200 83P

A low pressure monitor for hybrid air bag systems for vehicles includes a pressure responsive disc 34. 6 exposed on one side to a reference pressure chamber 34. 11 and on the other side to the pressure in an air bag bottle 40 and positioned adjacent a movable arm 28. 10 of an electric switch, The switch includes an electrically conductive sheet having a first portion partially encased in a base 26 of electrically insulative material and being connected to a first terminal 14 and a second portion forming the movable contact arm 28. 10 extending from the insulative material and culminating with a portion formed with contact rib 28. 14 adapted to be received beneath a laterally extending stationary contact portion 22 of a second terminal 16. Tabs 28. 4, 28. 6 extend from the sheet out of the insulative material for connection to a resistor 30 mounted on the electrically insulative base and a frangible portion 28. 7 of the first portion is severed to place the resistor in series with the electrical contacts, The monitor is disposed in an air bag bottle with the disc 34.

2018014, May 24, 2018

Nov 30, 2016

15/364659

- Boston MA, US
Farren J. Isaacs - Brookline MA, US
Charles R. Cantor - Del Mar CA, US
Daniel J. Dwyer - Brookline MA, US

TRUSTEES OF BOSTON UNIVERSITY - Boston MA

C12N 15/67
C12Q 1/6897
C12N 15/11

The present invention provides nucleic acid molecules, DNA constructs, plasmids, and methods for post-transcriptional regulation of gene expression using RNA molecules to both repress and activate translation of an open reading frame. Repression of gene expression is achieved through the presence of a regulatory nucleic acid element (the cis-repressive RNA or crRNA) within the 5′ untranslated region (5′ UTR) of an mRNA molecule. The nucleic acid element forms a hairpin (stem/loop) structure through complementary base pairing. The hairpin blocks access to the mRNA transcript by the ribosome, thereby preventing translation. In particular, in embodiments of the invention designed to operate in prokaryotic cells, the stem of the hairpin secondary structure sequesters the ribosome binding site (RBS). In embodiments of the invention designed to operate in eukaryotic cells, the stem of the hairpin is positioned upstream of the start codon, anywhere within the 5′ UTR of an mRNA. A small RNA (trans-activating RNA, or taRNA), expressed in trans, interacts with the crRNA and alters the hairpin structure. This alteration allows the ribosome to gain access to the region of the transcript upstream of the start codon, thereby activating transcription from its previously repressed state.