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Daniel M Lockhart, 388008 Seawall Blvd UNIT 255, Galveston, TX 77551

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Galveston, TX   

Saint Johns, MI   

933 Monroe Rd, Saint Louis, MI 48880    989-6818094   

402 Grand River Rd, Laingsburg, MI 48848    517-6516257   

8531 La Prada Dr, Dallas, TX 75228    214-6608331   

Mesquite, TX   

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Daniel Lockhart

Location:
United States

Publications & IP owners

Us Patents

Compositions And Methods Of Making Sustained Release Liquid Formulations

US Patent:
8318210, Nov 27, 2012
Filed:
Feb 28, 2005
Appl. No.:
11/068124
Inventors:
Mark Tengler - Colleyville TX, US
Paul Taskey - Richland Hills TX, US
Daniel Lockhart - Euless TX, US
Russ McMahen - Flower Mound TX, US
Assignee:
Neos Therapeutics, LP - Grand Prairie TX
International Classification:
A61K 9/14
US Classification:
424501, 424400, 424490
Abstract:
The present invention includes compositions and methods for the controlled release of active agents in a shelf-stable liquid formulation by blending one or more controlled release microbeads comprising one or more active agents, preparing a dense, thixotropic solution having a density that is at, or about, the density of the one or more microbeads comprising a thixotropic agent, water and one or more preservatives under conditions that reduce bubble formation and mixing the microbeads and the thixotropic solutions in a mixer that lacks scraping paddles.

Method Of Formulating And Designing Liquid Drug Suspensions Containing Ion Exchange Resin Particles

US Patent:
8470375, Jun 25, 2013
Filed:
Jan 5, 2011
Appl. No.:
12/985340
Inventors:
Russell McMahen - Flower Mound TX, US
Mark Tengler - Colleyville TX, US
Michael Sloane - Fort Worth TX, US
Daniel Lockhart - Euless TX, US
Assignee:
NEOS Therapeutics, LP - Grand Prairie TX
International Classification:
A61K 9/50
US Classification:
424501
Abstract:
The invention relates to the formulation and quality control of liquid drug suspensions. In particular, the invention relates to methods of formulating liquid suspensions comprising drug-containing resin particles. The invention also relates to methods of confirming the acceptability of drug-containing resin particles for use in formulating liquid drug suspensions. The invention further relates to methods of formulating liquid suspensions in which drug-containing resin particles, the liquid suspension, or both are modified to achieve a desired in vitro dissolution profile. The invention also relates to a novel dissolution method and methods of predicting in vivo bioequivalence based on in vitro dissolution methods.

Methods Of Formulating And Designing Liquid Drug Suspensions Containing Ion Exchange Resin Particles

US Patent:
8512759, Aug 20, 2013
Filed:
Jun 7, 2012
Appl. No.:
13/490697
Inventors:
Russell McMahen - Flower Mound TX, US
Mark Tengler - Colleyville TX, US
Michael Sloane - Forth Worth TX, US
Daniel Lockhart - Euless TX, US
Assignee:
Neos Therapeutics, LP - Grand Prairie TX
International Classification:
A61K 9/50
A61K 9/14
A61K 31/74
US Classification:
424501, 424 781, 424486
Abstract:
The invention relates to the formulation and quality control of liquid drug suspensions. In particular, the invention relates to methods of formulating liquid suspensions comprising drug-containing resin particles. The invention also relates to methods of confirming the acceptability of drug-containing resin particles for use in formulating liquid drug suspensions. The invention further relates to methods of formulating liquid suspensions in which drug-containing resin particles, the liquid suspension, or both are modified to achieve a desired in vitro dissolution profile. The invention also relates to a novel dissolution method and methods of predicting in vivo bioequivalence based on in vitro dissolution methods.

Compositions And Methods Of Making Sustained Release Liquid Formulations

US Patent:
2013008, Apr 4, 2013
Filed:
Nov 26, 2012
Appl. No.:
13/685496
Inventors:
Mark Tengler - Colleyville TX, US
Paul Taskey - Richard Hills TX, US
Daniel Lockhart - Euless TX, US
Russell McMahen - Flower Mound TX, US
Assignee:
NEOS THERAPEUTICS, LP - Grand Prairie TX
International Classification:
A61K 9/10
US Classification:
424492, 424497, 514653, 514357, 514289, 424491, 424494, 424493
Abstract:
The present invention includes compositions and methods for the controlled release of active agents in a shelf-stable liquid formulation by blending one or more controlled release microbeads comprising one or more active agents, preparing a dense, thixotropic solution having a density that is at, or about, the density of the one or more microbeads comprising a thixotropic agent, water and one or more preservatives under conditions that reduce bubble formation and mixing the microbeads and the thixotropic solutions in a mixer that lacks scraping paddles.

Methods Of Formulating And Designing Liquid Drug Suspensions Containing Ion Exchange Resin Particles

US Patent:
2014003, Feb 6, 2014
Filed:
May 29, 2013
Appl. No.:
13/904739
Inventors:
Russell McMAHEN - Flower Mound TX, US
Mark Tengler - Colleyville TX, US
Michael Sloane - Forth Worth TX, US
Daniel Lockhart - Euless TX, US
Assignee:
NEOS THERAPEUTICS, LP - Grand Prairie TX
International Classification:
G01N 15/06
US Classification:
73 6171
Abstract:
The invention relates to the formulation and quality control of liquid drug suspensions. In particular, the invention relates to methods of formulating liquid suspensions comprising drug-containing resin particles. The invention also relates to methods of confirming the acceptability of drug-containing resin particles for use in formulating liquid drug suspensions. The invention further relates to methods of formulating liquid suspensions in which drug-containing resin particles, the liquid suspension, or both are modified to achieve a desired in vitro dissolution profile. The invention also relates to a novel dissolution method and methods of predicting in vivo bioequivalence based on in vitro dissolution methods.

Compositions And Methods Of Making Sustained Release Liquid Formualtions

US Patent:
2014009, Apr 3, 2014
Filed:
Oct 3, 2013
Appl. No.:
14/045671
Inventors:
Mark TENGLER - Colleyville TX, US
Paul Taskey - Richard Hills TX, US
Daniel Lockhart - Euless TX, US
Russell McMahen - Flower Mound TX, US
Assignee:
NEOS THERAPEUTICS, LP - Grand Prairie TX
International Classification:
A61K 9/50
US Classification:
424494, 514289, 514653, 514357
Abstract:
The present invention includes compositions and methods for the controlled release of active agents in a shelf-stable liquid formulation by blending one or more controlled release microbeads comprising one or more active agents, preparing a dense, thixotropic solution having a density that is at, or about, the density of the one or more microbeads comprising a thixotropic agent, water and one or more preservatives under conditions that reduce bubble formation and mixing the microbeads and the thixotropic solutions in a mixer that lacks scraping paddles.

Isbn (Books And Publications)

Making Effective Use Of Mailed Questionnaires

Author:
Daniel C. Lockhart
ISBN #:
0875897827

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