David Derosier resumes & CV records
Resumes
David Derosier
David Derosier
David J Derosier, 8527 Chesterfield Rd, Newton, MA 02465
David Derosier Phones & Addresses
27 Chesterfield Rd, West Newton, MA 02465 617-9645917 617-9655612
Newton Center, MA
Sioux Falls, SD
Warrenton, VA
Nashua, NH
Waltham, MA
Arlington, MA
Belmont, MA
27 Chesterfield Rd, West Newton, MA 02465 617-7849867
Work
Position:
Handlers, Equipment Cleaners, Helpers, and Laborers Occupations
Education
Degree:
Associate degree or higher
Mentions for David J Derosier
Publications & IP owners
Us Patents
Clonable Tag For Purification And Electron Microscopy Labeling
US Patent:
2009023, Sep 24, 2009
Filed:
Dec 16, 2005
Appl. No.:
11/793282
Inventors:
David Derosier - Newton MA, US
Christopher P. Mercogliano - Neptune City NJ, US
Christopher P. Mercogliano - Neptune City NJ, US
Assignee:
BRANDEIS UNIVERSITY - Waltham MA
International Classification:
G01N 33/68
C12Q 1/02
C12Q 1/68
C12Q 1/02
C12Q 1/68
US Classification:
435 6, 435 29, 435 405
Abstract:
The disclosure provides compositions and methods for heavy atom labeling of a target protein using a clonable tag. The clonable tag comprises a metal binding protein, or fragment thereof, such as metallothionein, which may be fused to a target protein of interest. The tag permits the target protein to be labeled with a heavy atom, such as gold, silver, or mercury, and thus permits visualization of the target protein by electron microscopy. Also provided are methods for purification of a target protein using metallothionein, or a fragment thereof, as an affinity tag. The metallothionein fusion may be purified on immobilized metal affinity chromatography (IMAC) column charged with a metal such as cadmium.
Cooling Systems And Methods For Cryo Super-Resolution Fluorescence Light Microscopy And Other Applications
US Patent:
2017024, Aug 31, 2017
Filed:
May 17, 2017
Appl. No.:
15/597506
Inventors:
- Waltham MA, US
David J. DEROSIER - Newton MA, US
Gina TURRIGIANO - Weston MA, US
Marc NAHMANI - Arlington MA, US
David J. DEROSIER - Newton MA, US
Gina TURRIGIANO - Weston MA, US
Marc NAHMANI - Arlington MA, US
International Classification:
G02B 21/28
G02B 21/32
G02B 21/26
G02B 21/33
G02B 21/32
G02B 21/26
G02B 21/33
Abstract:
New systems and methods are described for maintaining a desired steady state temperature differential between two objects that may otherwise undergo heat transfer to restore thermal steady state. In one application, a cooling microscope assembly and its use with conventional optical microscopes are described for achieving super-resolution imaging. The assembly allows for the high resolution imaging of samples at cryogenic temperatures while maintaining the temperature of the objective lens above freezing by employing circulation systems and a coupling fluid between the sample and objective lens.
Isbn (Books And Publications)
Electron Crystallography Of Biological Macromolecules
Author:
David Derosier
ISBN #:
0195088719
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