David L Gresham Deceased6 Medallion Ln, Willingboro, NJ 08046

2009026, Oct 22, 2009

Jan 12, 2007

12/160266

David Gresham - Princeton NJ, US
David Botstein - Princeton NJ, US
Leonid Kruglyak - Princeton NJ, US
Douglas Ruderfer - Cambridge MA, US
Stephen Pratt - Phoenix AZ, US

The Trustees of Princeton University - Princeton NJ

C40B 30/04
C12Q 1/68
C40B 40/06

506 9, 435 6, 506 16

Disclosed herein is a system useful for detecting sequence differences (e.g., single-nucleotide polymorphisms) between genomes using data from a single hybridization with a genomic DNA microarray, such as a whole-genome array. The methods described herein can be used to detect, simply and inexpensively, differences in sequence among the genomes of individual members of a species, for example. In examples described herein, the system and methods were used to detect a variety of spontaneous single base-pair substitutions, insertions and deletions, and most (>90%) of the approximately 30,000 known single-nucleotide polymorphisms between two strains. The system and methods were also used to elucidate the genetic basis of phenotypic variants and identify the small number of single base-pair changes accumulated during experimental evolution of yeast.

5774540, Jun 30, 1998

Nov 15, 1995

8/559517

Joanne W. Davidson - Keansburg NJ
William F. Dudley - Jackson NJ
David A. Fishman - Lakewood NJ
David M. Gresham - East Hampton NY
Kenneth Kasiske - Jackson NJ
Michael L. Moroze - Broomfield CO
Elizabeth Bauer-Nilsen Sanders - Columbus OH
Alessandro A. Subrizi - San Francisco CA
Susan L. Tuttle - East Windsor NJ

Lucent Technologies Inc. - Murray Hill NJ

H04M 100

379387

A user of a telephone terminal with an interactive display is provided complete access to all feature choices in a hierarchical menu through a minimum number of menu keys. These menu keys include a "Next" key, a "Back" key, a "Select" key and a "Home" key. These menu keys occupy minimal space on the housing of the telephone terminal, yet enable the user of the terminal to easily scroll to and select every feature in the interactive display. The user is able to quickly develop a mental model of the feature choices and easily navigate through these menu selections. Context-sensitive functionality also is provided for using the interactive display. As a user completes a command function, the feature choice presented to the user for this function is the one most likely to be accessed by the user, thus advantageously avoiding the necessity of having a dedicated key for allowing the user to select this feature choice.

5841855, Nov 24, 1998

Nov 15, 1995

8/559516

Joanne W. Davidson - Keansburg NJ
William F. Dudley - Jackson NJ
David M. Gresham - East Hampton NY
Michael L. Moroze - Broomfield CO
Elizabeth Bauer-Nilsen Sanders - Columbus OH
Alessandro A. Subrizi - San Francisco CA
Susan L. Tuttle - East Windsor NJ

Lucent Technologies Inc. - Murray Hill NJ

H04M 100
H04M 342

379387

A menu level indicator facilitates ease of use of a telephone terminal by a user by providing easily understandable information about selectable menu options available in an interactive display on the telephone terminal. The menu level indicator provides a visual indication for permitting the user to directly determine the number of menu options available while at one of multiple selectable menu levels in the menu. The menu level indicator also provides a visual indication for the user as to the relative position of a displayed, selectable menu option with respect to other selectable menu options commonly located at one of the multiple selectable menu levels. As a user maneuvers through the menu levels, such user is able to quickly develop a mental model of the feature menus and easily navigate through these menu selections.