David E Kasler, 74487 Sycamore Dr, Circleville, OH 43113

2020037, Dec 3, 2020

Aug 21, 2020

16/999193

- Columbus OH, US
David KASLER - Ashville OH, US
Emily CAMPBELL - New Albany OH, US

C12M 1/26
C12P 21/00
C07K 14/195
C12M 1/34
C12M 1/36

An apparatus produces a target metabolite in a bioreaction. The apparatus has a reactor vessel that contains a bulk liquor in which the bioreaction is conducted, with a headspace provided above the bulk liquor. In some instances, the target metabolite is favorably partitioned into a foam formed at an interface of the bulk liquor and the headspace. A foam collector is arranged to receive this foam from the bioreactor and break it into a condensed foam liquid, from which the target metabolite may be isolated and purified. In one exemplary application, paenibacillin is produced by fermentation of a medium by OSY-DF, and is preferentially concentrated in the foam. In another exemplary application, fermentation of a medium by GF610 produces amyloliquecidin GF610 is which is preferentially concentrated in the foam.

2017011, Apr 27, 2017

Jan 6, 2017

15/399777

- Columbus OH, US
David Kasler - Ashville OH, US

OHIO STATE INNOVATION FOUNDATION - Columbus OH

G01N 25/00
G01K 7/02
A23L 15/00
G01N 33/08

A thermal simulator simulates the thermal behavior of items such as eggs for which the actual internal temperature profile is difficult to measure. A yolk body simulates the egg yolk, an albumen body surrounds the yolk body and simulates the egg albumen, and a shell layer surrounds the albumen body to simulate the shell. The thermal properties of the materials forming the egg body, albumen body and shell layer are tuned to match the thermal properties of the egg yolk, egg albumen and egg shell. Thermometric devices are positioned within the egg body and egg albumen along with communication devices which process signals from the thermometric devices indicative of temperature and communicate these signals to a computer for further processing and display.

2014036, Dec 18, 2014

Jun 18, 2013

13/920165

- Columbus OH, US
David Kasler - Ashville OH, US

G01K 3/14
G01N 33/08
G01K 13/00

374137

A thermal simulator simulates the thermal behavior of items such as eggs for which the actual internal temperature profile is difficult to measure. A yolk body simulates the egg yolk, an albumen body surrounds the yolk body and simulates the egg albumen, and a shell layer surrounds the albumen body to simulate the shell. The thermal properties of the materials forming the egg body, albumen body and shell layer are tuned to match the thermal properties of the egg yolk, egg albumen and egg shell. Thermometric devices are positioned within the egg body and egg albumen along with communication devices which process signals from the thermometric devices indicative of temperature and communicate these signals to a computer for further processing and display.