David H Riege, 38Bellevue, WA

4567149, Jan 28, 1986

Mar 17, 1983

6/476367

William J. Sell - San Francisco CA
David H. Riege - Newark CA
Vincent A. Marinkovich - Palo Alto CA

Mast Immunosystems, Ltd. - Mountain View CA

G01N 33053
G01N 2306
C12M 100
C01N 33544

436513

Method and apparatus for use in the diagnostic analysis of a liquid specimen through binding assays. The apparatus includes a rigid body having an elongated, shallow well formed in it, with a plurality of elongated strips, preferably in the form of cotton threads, stretched across the well in spaced relationship and generally perpendicular to the well's longitudinal axis. Each thread is coated with a separate binding conjugate such as an antigen or allergen. A cover plate that includes a thin plastic layer and an overlaying thin metallic layer covers the well to form an enclosed chamber having a specific volume. The metallic layer includes a separate elongated aperture in alignment with each coated thread. A liquid specimen is introduced into the chamber through one of two ports, for incubation with the coated threads, after which the specimen is removed and the reaction that occurred on each thread is determined.

4510393, Apr 9, 1985

Apr 15, 1983

6/485172

William J. Sell - San Francisco CA
Joel M. Peisach - Madden MA
David H. Riege - Newark CA

Mast Immunosystems, Ltd. - Mt. View CA

G01N 2300
G01T 1167
G01T 700

2504752

A portable photo chamber for photographically recording the extent of a chemical reaction such as in an immunological test, wherein a substrate emitting radiation such as gamma radiation is supported in facing contact with a film and with intensifying means, so that exposure time is reduced as a result of emission of further radiation such as a visible light from the intensifying means and its recording on the film. The photo chamber includes retaining means for supporting the substrate, which itself is preferably enclosed in a container such as a pipette, and translating means for moving the substrate into closely facing relationship to the film and also to a spaced-apart position within the chamber. In a preferred embodiment, the photo chamber utilizes an instant photographic system with film processing means attached to the chamber, so that the photo chamber is both portable and self-contained for use in remote locations.

D285486, Sep 2, 1986

Jan 16, 1984

6/570957

Vincent A. Marinkovich - Palo Alto CA
William J. Sell - San Francisco CA
David H. Riege - Newark CA

Mast Immunosystems, Ltd. - Mountain View CA

D24 29

4558013, Dec 10, 1985

Apr 8, 1983

6/483292

Vincent A. Marinkovich - Palo Alto CA
David H. Riege - Newark CA
John W. Dyminski - Cupertino CA

Mast Immunosystems, Ltd. - Mountain View CA

G01N 3358
G01N 2100

436513

Method and apparatus for use in accurately measuring the binding reactions occurring between a predetermined class of components in a liquid specimen and their corresponding binding conjugates coated on separate test regions of a carrier. The carrier further includes a reference region that is uncoated, and the carrier is adapted for simultaneous contact of all of its regions with the liquid specimen. Any resulting binding reaction on each test region indicates both specific binding to the coated component as well as non-specific binding, and any resulting binding reaction on the reference region indicates merely non-specific binding. The measurements for the test regions are all reduced by an amount determined in accordance with the measurement for the reference region, to reduce the effects of non-specific binding on those measurements and thereby provide accurate measurements of the specific binding on each coated component.

2021009, Apr 1, 2021

Sep 27, 2019

16/586567

- San Francisco CA, US
David Halsted Riege - San Francisco CA, US
Maksim Rozentsveyg - New York NY, US

G01C 21/34
G06Q 50/30

The present disclosure relates to systems, non-transitory computer-readable media, and methods for selectively coalescing stop locations of route options in a dynamic transportation matching system. In one or more embodiments, the coalescing controller system generates route scores for driving route options, including route scores for an optimal non-coalesced driving route option and a coalesced driving route option. In some embodiments, the route score can include a driving score, a walking score, and a coalescing factor. Based on the route scores, the coalescing controller system can determine to coalesce stop locations. For example, if the route score of the coalesced driving route option is lower than the non-coalesced driving route option, the coalescing controller system can determine to coalesce stop locations in accordance with the coalesced driving route option. Additionally, the coalescing controller system can send instructions to a transportation provider device in accordance with the coalesced driving route option.

2021004, Feb 18, 2021

Aug 13, 2019

16/539850

- San Francisco CA, US
Michael Sasha Frumin - Brooklyn NY, US
Dorian Anthony Goldman - Brooklyn NY, US
Man Geen Harold Li - New York NY, US
Akshay Ramesh Patil - Brooklyn NY, US
David Halsted Riege - San Francisco CA, US
Kevin Stewart - Seattle WA, US
Alexander Michael Weinstein - Seattle WA, US

G08G 1/00
G01C 21/34
G06F 17/18

This disclosure describes a pickup location determination system that determines a pickup location for a received transportation request by filtering out door points based on various factors and by utilizing a pickup location model to select a pickup location from the filtered door points. For example, the disclosed systems generate door points relative to intersection points within a request radius of a request location associated with a received transportation request. The disclosed systems generate potential pickup locations by filtering out door points that are impractical and/or inefficient based on proximity to other door points, locations relative to venues, locations relative to side streets, and/or locations between parallel road segments (e.g., medians). The disclosed systems further utilize a pickup location model to select a pickup location from the potential pickup locations.