David Ryckman resumes & CV records
Resumes
David Ryckman
Location:
United States
David Ryckman
Location:
Greater Seattle Area
Industry:
Pharmaceuticals
David B Ryckman, 8811615 28Th Ave SW, Burien, WA 98146
David Ryckman Phones & Addresses
11615 28Th Ave SW, Seattle, WA 98146 206-4398442
1524 46Th St, Seattle, WA 98116 206-9329305
Burien, WA
Moscow, ID
1041 Woods Ferry Rd, Gallatin, TN 37066 615-4516897
1041 Woods Ferry Rd #14, Gallatin, TN 37066 615-4516897
Mentions for David B Ryckman
Publications & IP owners
Us Patents
Substituted Benzimidazoles And Methods Of Preparation
US Patent:
7767820, Aug 3, 2010
Filed:
May 5, 2008
Appl. No.:
12/151995
Inventors:
Martin Dimitroff - Seattle WA, US
Bridget R. Miller - Lynnwood WA, US
Brady S. Stillwell - Gregory MI, US
David A. Siesel - San Diego CA, US
Tyson Swiftney - Bellevue WA, US
Brian Diaz - Seattle WA, US
Danlin Gu - Kirkland WA, US
Jonathan P. Van Dyck - Seattle WA, US
David Ryckman - Bellevue WA, US
Daniel J. Poon - Oakland CA, US
Teresa E. Pick - Danville CA, US
Bridget R. Miller - Lynnwood WA, US
Brady S. Stillwell - Gregory MI, US
David A. Siesel - San Diego CA, US
Tyson Swiftney - Bellevue WA, US
Brian Diaz - Seattle WA, US
Danlin Gu - Kirkland WA, US
Jonathan P. Van Dyck - Seattle WA, US
David Ryckman - Bellevue WA, US
Daniel J. Poon - Oakland CA, US
Teresa E. Pick - Danville CA, US
Assignee:
Novartis Vaccines and Diagnostics, Inc. - Emeryville CA
International Classification:
C07D 401/14
US Classification:
5462734
Abstract:
Methods for preparing new substituted benzimidazole compounds having formula (I) useful for treating kinase mediated disorders are provided wherein R, R, R, R, a, b, and c are defined herein.
Inhibition Of Fgfr3 And Treatment Of Multiple Myeloma
US Patent:
7825132, Nov 2, 2010
Filed:
Nov 5, 2004
Appl. No.:
10/983174
Inventors:
Shaopei Cai - Seattle WA, US
Joyce Chou - El Cerrito CA, US
Eric Harwood - Seattle WA, US
Carla C. Heise - Benicia CA, US
Timothy D. Machajewski - Martinez CA, US
David Ryckman - Bellevue WA, US
Xiao Shang - Bellevue WA, US
Marion Wiesmann - Brisbane CA, US
Shuguang Zhu - Shoreline WA, US
Joyce Chou - El Cerrito CA, US
Eric Harwood - Seattle WA, US
Carla C. Heise - Benicia CA, US
Timothy D. Machajewski - Martinez CA, US
David Ryckman - Bellevue WA, US
Xiao Shang - Bellevue WA, US
Marion Wiesmann - Brisbane CA, US
Shuguang Zhu - Shoreline WA, US
Assignee:
Novartis Vaccines and Diagnostics, Inc. - Emeryville CA
International Classification:
A61K 31/47
A01N 43/40
A01N 43/40
US Classification:
514314
Abstract:
Methods of inhibiting fibroblast growth factor receptor 3 and treating various conditions mediated by fibroblast growth factor receptor 3 are provided that include administering to a subject a compound of Structure I, a pharmaceutically acceptable salt thereof, a tautomer thereof, or a pharmaceutically acceptable salt of the tautomer. Compounds having the Structure I have the following structure where and have the variables described herein. Such compounds may be used to prepare medicaments for use in inhibiting fibroblast growth factor receptor 3 and for use in treating conditions mediated by fibroblast growth factor receptor 3 such as multiple myeloma.
Macrolide Formulations For Inhalation And Methods Of Treatment Of Endobronchial Infections
US Patent:
2004002, Feb 5, 2004
Filed:
Aug 12, 2003
Appl. No.:
10/333948
Inventors:
William Baker - Bellevue WA, US
Peter Challoner - Seattle WA, US
Ribhi Shawar - Bellevue WA, US
Kay Huh - Emeryville CA, US
David Ryckman - Bellevue WA, US
Peter Challoner - Seattle WA, US
Ribhi Shawar - Bellevue WA, US
Kay Huh - Emeryville CA, US
David Ryckman - Bellevue WA, US
International Classification:
A61K031/70
A61K031/7048
A61L009/04
A61K031/7048
A61L009/04
US Classification:
424/045000, 514/028000, 514/029000, 128/200230
Abstract:
Macrolide formulations, such as an erythromycylamine formulation, for delivery by aerosolization are described. The concentrated erythromycylamine formulations contain an amount of erythromycylamine effective to treat infections caused by susceptible bacteria. Unit dose devices having a container containing a formulation of the macrolide antibiotic in a physiologically acceptable carrier are also described. Methods for treatment of pulmonary infections by a formulation (liquid solution, suspension, or dry powder) delivered as an aerosol having mass median aerodynamic diameter predominantly between 1 to 5 m are also described.
Methods For Synthesizing Quinolinone Compounds
US Patent:
2005013, Jun 23, 2005
Filed:
Nov 5, 2004
Appl. No.:
10/982757
Inventors:
Shaopei Cai - Seattle WA, US
Joyce Chou - El Cerrito CA, US
Eric Harwood - Seattle WA, US
Timothy Machajewski - Martinez CA, US
David Ryckman - Bellevue WA, US
Xiao Shang - Bellevue WA, US
Shuguang Zhu - Shoreline WA, US
Augustus Okhamafe - Concord CA, US
Marc Tesconi - Monroe NY, US
Joyce Chou - El Cerrito CA, US
Eric Harwood - Seattle WA, US
Timothy Machajewski - Martinez CA, US
David Ryckman - Bellevue WA, US
Xiao Shang - Bellevue WA, US
Shuguang Zhu - Shoreline WA, US
Augustus Okhamafe - Concord CA, US
Marc Tesconi - Monroe NY, US
International Classification:
A61K031/496
C07D043/14
C07D043/14
US Classification:
544363000, 546157000
Abstract:
A method of synthesizing a substituted or unsubstituted 4-amino-3-benzimidazolyl quinolinone compound includes reacting a first compound having the formula I with a second compound having the formula II in a suitable solvent in the presence of a sodium or potassium salt of a base. The first compound and the second compound have the following structures where the variables have the values described herein:
Pharmaceutically Acceptable Salts Of Quinolinone Compounds Having Improved Pharmaceutical Properties
US Patent:
2005020, Sep 22, 2005
Filed:
Nov 5, 2004
Appl. No.:
10/982543
Inventors:
Shaopei Cai - Seattle WA, US
Joyce Chou - El Cerrito CA, US
Eric Harwood - Seattle WA, US
Timothy Machajewski - Martinez CA, US
David Ryckman - Bellevue WA, US
Xiao Shang - Bellevue WA, US
Shuguang Zhu - Shoreline WA, US
Augustus Okhamafe - Concord CA, US
Marc Tesconi - Monroe NY, US
Joyce Chou - El Cerrito CA, US
Eric Harwood - Seattle WA, US
Timothy Machajewski - Martinez CA, US
David Ryckman - Bellevue WA, US
Xiao Shang - Bellevue WA, US
Shuguang Zhu - Shoreline WA, US
Augustus Okhamafe - Concord CA, US
Marc Tesconi - Monroe NY, US
International Classification:
A61K031/496
A61K031/4709
C07D043/14
A61K031/4709
C07D043/14
US Classification:
514253070, 514312000, 546157000, 544363000
Abstract:
A lacate salt of a compound of Formula I or a tautomer of the compound, wherein Formula I has the following structure and R-Rand R-Rare as defined herein
Substituted Benzimidazoles And Methods Of Preparation
US Patent:
2007004, Mar 1, 2007
Filed:
Aug 30, 2006
Appl. No.:
11/513745
Inventors:
Martin Dimitroff - Seattle WA, US
Bridget Miller - Lynnwood WA, US
Brady Stillwell - Gregory MI, US
David Siesel - San Diego CA, US
Tyson Swiftney - Bellevue WA, US
Brian Diaz - Seattle WA, US
Danlin Gu - Kirkland WA, US
Jonathan van Dyck - Seattle WA, US
David Ryckman - Bellevue WA, US
Daniel Poon - Oakland CA, US
Teresa Pick - Danville CA, US
Bridget Miller - Lynnwood WA, US
Brady Stillwell - Gregory MI, US
David Siesel - San Diego CA, US
Tyson Swiftney - Bellevue WA, US
Brian Diaz - Seattle WA, US
Danlin Gu - Kirkland WA, US
Jonathan van Dyck - Seattle WA, US
David Ryckman - Bellevue WA, US
Daniel Poon - Oakland CA, US
Teresa Pick - Danville CA, US
International Classification:
A61K 31/4439
C07D 403/14
C07D 403/14
US Classification:
514338000, 546272400
Abstract:
Methods for preparing new substituted benzimidazole compounds having formula (I) useful for treating kinase mediated disorders are provided wherein R, R, R, R, a, b, and c are defined herein
Pharmaceutically Acceptable Salts Of Quinolinone Compounds Having Improved Pharmaceutical Properties
US Patent:
2009018, Jul 16, 2009
Filed:
Mar 4, 2009
Appl. No.:
12/398130
Inventors:
Shaopei Cai - Seattle WA, US
Joyce Chou - El Cerrito CA, US
Eric Harwood - Seattle WA, US
Timothy Machajewski - Martinez CA, US
David Ryckman - Bellevue WA, US
Xiao Shang - Bellevue WA, US
Shuguang Zhu - Shoreline WA, US
Augustus O. Okhamafe - Concord CA, US
Marc S. Tesconi - Monroe NY, US
Joyce Chou - El Cerrito CA, US
Eric Harwood - Seattle WA, US
Timothy Machajewski - Martinez CA, US
David Ryckman - Bellevue WA, US
Xiao Shang - Bellevue WA, US
Shuguang Zhu - Shoreline WA, US
Augustus O. Okhamafe - Concord CA, US
Marc S. Tesconi - Monroe NY, US
International Classification:
A61K 31/496
C07D 401/14
C07D 401/14
US Classification:
51425307, 544363
Abstract:
A lacate salt of a compound of Formula I or a tautomer of the compound, wherein Formula I has the following structure and R-Rand R-Rare as defined herein
Substituted Benzimidazoles And Methods Of Preparation
US Patent:
2010025, Oct 7, 2010
Filed:
Jun 18, 2010
Appl. No.:
12/818971
Inventors:
Martin Dimitroff - Seattle WA, US
Bridget R. Miller - Mynnwood WA, US
Brady S. Stillwell - Gregory MI, US
David A. Siesel - San Diego CA, US
Tyson Swiftney - Bellenue WA, US
Brian Diaz - Seattle WA, US
Danlin Gu - Kirkland WA, US
Jonathan P. van Dyck - Seattle WA, US
David Ryckman - Bellevue WA, US
Daniel J. Poon - Oakland CA, US
Teresa E. Pick - Danville CA, US
Bridget R. Miller - Mynnwood WA, US
Brady S. Stillwell - Gregory MI, US
David A. Siesel - San Diego CA, US
Tyson Swiftney - Bellenue WA, US
Brian Diaz - Seattle WA, US
Danlin Gu - Kirkland WA, US
Jonathan P. van Dyck - Seattle WA, US
David Ryckman - Bellevue WA, US
Daniel J. Poon - Oakland CA, US
Teresa E. Pick - Danville CA, US
International Classification:
C07D 403/14
C07D 401/14
C07D 401/14
US Classification:
544364, 5462734, 546256
Abstract:
Methods for preparing new substituted benzimidazole compounds having formula (I) useful for treating kinase mediated disorders are provided wherein R, R, R, R, a, b, and c are defined herein
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