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David J Standring8 Burnley Rd, Norwood, MA 02062

David Standring Phones & Addresses

8 Burnley Rd, Norwood, MA 02062    781-4409891   

20 Rosemary St, Norwood, MA 02062    781-4409891   

242 Sea Ave, West Yarmouth, MA 02673    508-7907094   

240 Sea Ave, West Yarmouth, MA 02673   

Worcester, MA   

255 Sycamore Dr, Holden, MA 01520    508-8296098   

Mentions for David J Standring

David Standring resumes & CV records

Resumes

David Standring Photo 21

Senior Manufacturing Engineer

Location:
242 south Sea Ave, West Yarmouth, MA 02673
Industry:
Medical Devices
Work:
Siemens Healthcare
Senior Manufacturing Engineer
Utc Fire & Security 2003 - 2008
Manufacturing Engineer
Texas Instruments 1995 - 2000
Manufacturing Engineer
Prestone Products Corporation 1995 - 1995
Manufacturing Engineer
Education:
Boston University 1991 - 1995
Bachelors, Mechanical Engineering
St. John's High School
David Standring Photo 22

David Standring

David Standring Photo 23

David Standring

Publications & IP owners

Us Patents

Β-L-2′-Deoxynucleosides For The Treatment Of Resistant Hbv Strains And Combination Therapies

US Patent:
7186700, Mar 6, 2007
Filed:
Sep 15, 2003
Appl. No.:
10/662641
Inventors:
David Standring - Milton MA, US
Jean-Pierre Sommadossi - Cambridge MA, US
April L. Patty - Medford MA, US
Maria Seifer - Clinton MA, US
Assignee:
Idenix Pharmaceuticals, Inc. - Cambridge MA
International Classification:
A01N 43/04
A61K 31/70
A61K 31/715
US Classification:
514 49, 42 43, 42 50, 42 51
Abstract:
It has been discovered that β-L-2′-deoxynucleosides are active against drug-resistant hepatitis B virus with mutations. A method for treating lamivudine resistant HBV (M552V) in a host is provided that includes administering a β-L-2′-deoxynucleoside or its pharmaceutically acceptable salt, ester or prodrug. In addition, a method for preventing lamivudine resistant HBV (M552V) mutation from occurring in a naïve host is provided that includes administering a β-L-2′-deoxynucleoside or its pharmaceutically acceptable salt, ester or prodrug. A method for preventing and/or suppressing the emergence of the HBV double mutant (L528M/M552V) in a host is also provided that includes administering a β-L-2′-deoxynucleoside or its pharmaceutically acceptable salt, ester or prodrug.

2′-Branched Nucleosides And Flaviviridae Mutation

US Patent:
7824851, Nov 2, 2010
Filed:
Nov 17, 2003
Appl. No.:
10/715729
Inventors:
Jean-Pierre Sommadossi - Boston MA, US
Paolo LaColla - Capoterra, IT
David Standring - Milton MA, US
Vadim Bichko - San Diego CA, US
Lin Qu - Webster TX, US
Assignee:
Idenix Pharmaceuticals, Inc. - Cambridge MA
Universita Degli Studi Di Cagliari - Cagliari
International Classification:
C12Q 1/70
C12Q 1/68
A01N 43/04
A61K 31/70
C07H 19/00
US Classification:
435 5, 435 6, 536 281, 536 282, 536 271, 514 49, 514 25, 514 50, 514 44
Abstract:
The present invention discloses a method for the treatment of Flaviviridae infection that includes the administration of a 2′-branched nucleoside, or a pharmaceutically acceptable prodrug and/or salt thereof, to a human in need of therapy in combination or alternation with a drug that directly or indirectly induces a mutation in the viral genome at a location other than a mutation of a nucleotide that results in a change from seine to a different amino acid in the highly conserved consensus sequence, XRXSGXXXT (Sequence ID No. 63), of domain B of the RNA polymerase region, or is associated with such a mutation. The invention also includes a method to detect a mutant strain of Flaviviridae and a method for its treatment.

Β-L-2′-Deoxynucleosides For The Treatment Of Resistant Hbv Strains And Combination Therapies

US Patent:
7928086, Apr 19, 2011
Filed:
Jan 9, 2007
Appl. No.:
11/651353
Inventors:
David Standring - Milton MA, US
Jean-Pierre Sommadossi - Cambridge MA, US
April L. Patty - Medford MA, US
Maria Seifer - Clinton MA, US
Assignee:
Novartis AG - Basel
International Classification:
A01N 43/04
A61K 31/70
A61K 31/715
US Classification:
514 49, 514 42, 514 43, 514 50, 514 51
Abstract:
It has been discovered that β-L-2′-deoxynucleosides are active against drug-resistant hepatitis B virus with mutations. A method for treating lamivudine resistant HBV (M552V) in a host is provided that includes administering a β-L-2′-deoxynucleoside or its pharmaceutically acceptable salt, ester or prodrug. In addition, a method for preventing lamivudine resistant HBV (M552V) mutation from occurring in a naïve host is provided that includes administering a β-L-2′-deoxynucleoside or its pharmaceutically acceptable salt, ester or prodrug. A method for preventing and/or suppressing the emergence of the HBV double mutant (L528M/M552V) in a host is also provided that includes administering a β-L-2′-deoxynucleoside or its pharmaceutically acceptable salt, ester or prodrug.

Β-L-2′-Deoxynucleosides For The Treatment Of Resistant Hbv Strains And Combination Therapies

US Patent:
8158606, Apr 17, 2012
Filed:
Mar 21, 2011
Appl. No.:
13/052750
Inventors:
David Standring - Milton MA, US
Jean-Pierre Sommadossi - Cambridge MA, US
April Patty - Medford MA, US
Maria Seifer - Clinton MA, US
Assignee:
Novartis, AG - Basel
International Classification:
A01N 43/04
A61K 31/70
A61K 31/715
US Classification:
514 49, 514 42, 514 43, 514 50, 514 51
Abstract:
It has been discovered that β-L-2′-deoxynucleosides are active against drug-resistant hepatitis B virus with mutations. A method for treating lamivudine resistant HBV (M552V) in a host is provided that includes administering a β-L-2′-deoxynucleoside or its pharmaceutically acceptable salt, ester or prodrug. In addition, a method for preventing lamivudine resistant HBV (M552V) mutation from occurring in a naïve host is provided that includes administering a β-L-2′-deoxynucleoside or its pharmaceutically acceptable salt, ester or prodrug. A method for preventing and/or suppressing the emergence of the HBV double mutant (L528M/M552V) in a host is also provided that includes administering a β-L-2′-deoxynucleoside or its pharmaceutically acceptable salt, ester or prodrug.

2'-Branched Nucleosides And Flaviviridae Mutation

US Patent:
2011012, Jun 2, 2011
Filed:
Oct 28, 2010
Appl. No.:
12/914914
Inventors:
Jean-Pierre Sommadossi - Boston MA, US
Paolo LaColla - Capoterra, IT
David N. Standring - Milton MA, US
Vadim Bichko - San Diego CA, US
Lin Qu - Webster TX, US
International Classification:
C12Q 1/70
C40B 40/06
US Classification:
435 5, 506 16
Abstract:
The present invention discloses a method for the treatment of Flaviviridae infection that includes the administration of a 2′-branched nucleoside, or a pharmaceutically acceptable prodrug and/or salt thereof, to a human in need of therapy in combination or alternation with a drug that directly or indirectly induces a mutation in the viral genome at a location other than a mutation of a nucleotide that results in a change from serine to a different amino acid in the highly conserved consensus sequence, XRXGXXXT, of domain B of the RNA polymerase region, or is associated with such a mutation; The invention also includes a method to detect a mutant strain of Flaviviridae and a method for its treatment.

2'-Branched Nucleosides And Flaviviridae Mutation

US Patent:
2016016, Jun 16, 2016
Filed:
Dec 16, 2015
Appl. No.:
14/972009
Inventors:
- Cambridge MA, US
- Monserrato, IT
David N. STANDRING - Milton MA, US
Vadim BICHKO - San Diego CA, US
Lin QU - Webster TX, US
International Classification:
A61K 31/7072
C12Q 1/70
C12Q 1/18
A61K 38/21
Abstract:
The present invention discloses a method for the treatment of Flaviviridae infection that includes the administration of a 2′-branched nucleoside, or a pharmaceutically acceptable prodrug and/or salt thereof, to a human in need of therapy in combination or alternation with a drug that directly or indirectly induces a mutation in the viral genome at a location other than a mutation of a nucleotide that results in a change from serine to a different amino acid in the highly conserved consensus sequence, XRXGXXXT (SEQ ID NO: 63), of domain B of the RNA polymerase region, or is associated with such a mutation. The invention also includes a method to detect a mutant strain of Flaviviridae and a method for its treatment.

2'-Branched Nucleosides And Flaviviridae Mutation

US Patent:
2014028, Sep 25, 2014
Filed:
Feb 18, 2014
Appl. No.:
14/183438
Inventors:
- Cambridge MA, US
Paolo LACOLLA - Capoterra, IT
David N. STANDRING - Milton MA, US
Vadim BICHKO - San Diego CA, US
Lin QU - Webster TX, US
Assignee:
Idenix Pharmaceuticals, Inc. - Cambridge MA
International Classification:
C12Q 1/70
C12Q 1/04
US Classification:
424 857
Abstract:
The present invention discloses a method for the treatment of Flaviviridae infection that includes the administration of a 2′-branched nucleoside, or a pharmaceutically acceptable prodrug and/or salt thereof, to a human in need of therapy in combination or alternation with a drug that directly or indirectly induces a mutation in the viral genome at a location other than a mutation of a nucleotide that results in a change from serine to a different amino acid in the highly conserved consensus sequence, XRXGXXXT (SEQ ID NO: 63), of domain B of the RNA polymerase region, or is associated with such a mutation. The invention also includes a method to detect a mutant strain of Flaviviridae and a method for its treatment.

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