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Dawei W Chen, 5525 Lisa Ct, Guilford, CT 06437

Known as:
Daiwei Chen Chen Dawei Chen Da Wei
Related to:
Alissa Chen 21

Dawei Chen Phones & Addresses

1117 Durham Rd, Guilford, CT 06437    860-7048341   

25 Lisa Ct, Guilford, CT 06437   

New Haven, CT   

Middletown, CT   

9635 Genesee Ave, San Diego, CA 92121   

La Jolla, CA   

Social networks

Dawei W Chen

Linkedin

Work

Company: Cary quadrangle, purdue university 2010 Position: Resident assistant

Education

School / High School: Purdue University- West Lafayette, IN May 2012 Specialities: Bachelors in General Health Sciences

Skills

Lead Change • Drug Discovery • Organic Chemistry • Medicinal Chemistry • Technology Transfer • Assay Development • Clinical Development • Adme • Drug Design • High Throughput Screening • Protein Purification • Lc Ms • Drug Development • Protein Chemistry • Pharmacology

Industries

Pharmaceuticals
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Dawei Chen resumes & CV records

Resumes

Dawei Chen Photo 29

Vice President, Medicinal Chemistry

Location:
158 Saddle Hill Dr, Middletown, CT 06457
Industry:
Pharmaceuticals
Work:
Shanghai De Novo Pharmatech
Vice President, Medicinal Chemistry The Scripps Research Institute Apr 1, 1999 - Mar 1, 2002
Research Associate Achillion Pharmaceuticals Apr 1, 1999 - Mar 1, 2002
Principal Scientist
Education:
Tokushima University, Japan 2013 - 2015
Doctorates, Doctor of Philosophy The University of Tokushima 1995 - 1999
Doctorates, Doctor of Philosophy, Organic Chemistry
Skills:
Lead Change, Drug Discovery, Organic Chemistry, Medicinal Chemistry, Technology Transfer, Assay Development, Clinical Development, Adme, Drug Design, High Throughput Screening, Protein Purification, Lc Ms, Drug Development, Protein Chemistry, Pharmacology
Dawei Chen Photo 30

Dawei Chen - Waterford, CT

Work:
Cary Quadrangle, Purdue University 2010 to 2012
Resident Assistant Delta Chi Fraternity 2009 to 2012 PASE 2008 to 2012
Board of Directors PASE 2008 to 2012 PASE 2009 to 2010
Boiler Volunteer Network Yale Prevention Research Center - New Haven, CT Jun 2007 to 2010
Internship/Work
Education:
Purdue University - West Lafayette, IN May 2012
Bachelors in General Health Sciences

Publications & IP owners

Us Patents

Substituted Aryl Thioureas And Related Compounds; Inhibitors Of Viral Replication

US Patent:
7094807, Aug 22, 2006
Filed:
Nov 18, 2003
Appl. No.:
10/716175
Inventors:
Dawei Chen - Middletown CT, US
Milind Deshpande - Madison CT, US
Andrew Thurkauf - Ridgefield CT, US
Avinash Phadke - Branford CT, US
Xiangzhu Wang - Branford CT, US
Yiping Shen - Branford CT, US
Cuixian Liu - Branford CT, US
Jesse Quinn - Windsor CT, US
Junko Ohkanda - Gakuennishi-machi, JP
Shouming Li - Cheshire CT, US
Assignee:
Achillion Pharmaceuticals, Inc. - New Haven CT
International Classification:
A61K 31/17
C07C 335/02
US Classification:
514584, 564 23, 564 26, 564 27, 564 28, 564 29, 514585
Abstract:
The invention provides compounds and pharmaceutically acceptable salts of Formula I wherein the variables A, A, R, R, V, W, X, Y, and Z are defined herein. Certain compounds of Formula I described herein which possess potent antiviral activity. The invention particularly provides compounds of Formula I that are potent and/or selective inhibitors of Hepatitis C virus replication. The invention also provides pharmaceutical compositions containing one or more compound of Formula I, or a salt, solvate, or acylated prodrug of such compounds, and one or more pharmaceutically acceptable carriers, excipients, or diluents. The invention further comprises methods of treating patients suffering from certain infectious diseases by administering to such patients an amount of a compound of Formula I effective to reduce signs or symptoms of the disease or disorder. These infectious diseases include viral infections, particularly HCV infections. The invention is particularly includes methods of treating human patients suffering from an infectious disease, but also encompasses methods of treating other animals, including livestock and domesticated companion animals, suffering from an infectious disease.

Substituted Aryl Acylthioureas And Related Compounds; Inhibitors Of Viral Replication

US Patent:
7365068, Apr 29, 2008
Filed:
May 17, 2005
Appl. No.:
11/131013
Inventors:
Avinash Phadke - Branford CT, US
Dawei Chen - Middletown CT, US
Milind Deshpande - Madison CT, US
Andrew Thurkauf - Ridgefield CT, US
Xiangzhu Wang - Branford CT, US
Yiping Shen - Branford CT, US
Cuixian Liu - Branford CT, US
Jesse Quinn - Windsor CT, US
Junko Ohkanda - Osaka, JP
Shouming Li - Cheshire CT, US
Assignee:
Achillion Pharmaceuticals, Inc. - New Haven CT
International Classification:
A61K 31/496
A61K 31/444
A61K 31/5377
C07D 211/78
C07D 401/02
C07D 401/06
C07D 413/02
C07D 413/06
US Classification:
5142355, 514355, 514357, 514336, 51425301, 544124, 544360, 546329, 546316
Abstract:
The invention provides compounds and pharmaceutically acceptable salts of Formula IThe invention further comprises methods of treating patients suffering from certain infectious diseases by administering to such patients an amount of a compound of Formula I effective to reduce signs or symptoms of the disease or disorder. These infectious diseases include viral infections, particularly HCV infections. The invention is particularly includes methods of treating human patients suffering from an infectious disease, but also encompasses methods of treating other animals, including livestock and domesticated companion animals, suffering from an infectious disease. Methods of treatment include administering a compound of Formula I as a single active agent or administering a compound of Formula I in combination with on or more other therapeutic agent.

Azabenzofuran Substituted Thioureas; Inhibitors Of Viral Replication

US Patent:
7439374, Oct 21, 2008
Filed:
Jan 5, 2005
Appl. No.:
11/029910
Inventors:
Andrew Thurkauf - Ridgefield CT, US
Dawei Chen - Middletown CT, US
Avinash Phadke - Branford CT, US
Shouming Li - Cheshire CT, US
Milind Deshpande - Madison CT, US
Assignee:
Achillion Pharmaceuticals, Inc. - New Haven CT
International Classification:
C07D 401/02
A61K 31/44
US Classification:
549471, 514397, 514469
Abstract:
The present invention provides compounds of Formula 1,Certain compounds of Formula 1 described herein possess potent antiviral activity. The invention also provides compounds of Formula 1 that are potent and/or selective inhibitors of Hepatitis C virus replication. The invention also provides pharmaceutical compositions containing one or more compounds of Formula 1, or a salt, solvate, or acylated prodrug of such compounds, and one or more pharmaceutically acceptable carriers, excipients, or diluents. The invention further comprises methods of treating patients suffering from certain infectious diseases by administering to such patients an amount of a compound of Formula 1 effective to reduce signs or symptoms of the disease. These infectious diseases include viral infections, particularly HCV infections. The invention is particularly includes methods of treating human patients suffering from an infectious disease, but also encompasses methods of treating other animals, including livestock and domesticated companion animals, suffering from an infectious disease.

Substituted Aryl Thioureas And Related Compounds; Inhibitors Of Viral Replication

US Patent:
7476686, Jan 13, 2009
Filed:
Dec 17, 2004
Appl. No.:
11/015300
Inventors:
Dawei Chen - Middletown CT, US
Milind Deshpande - Madison CT, US
Andrew Thurkauf - Ridgefield CT, US
Avinash Phadke - Branford CT, US
Xiangzhu Wang - Branford CT, US
Yiping Shen - Branford CT, US
Cuixian Liu - Branford CT, US
Jesse Quinn - Windsor CT, US
Junko Ohkanda - Gakuennishi-machi, JP
Shouming Li - Cheshire CT, US
Assignee:
Achillion Pharmaceuticals, Inc. - New Haven CT
International Classification:
A61K 31/44
C07D 213/46
US Classification:
514355, 546316, 546225, 546152, 544162, 548146, 548215, 548469, 548530, 549 49, 549 70, 549357, 549425, 549462
Abstract:
The invention provides compounds and pharmaceutically acceptable salts of Formula IThe invention further comprises methods of treating patients suffering from certain infectious diseases by administering to such patients an amount of a compound of Formula I effective to reduce signs or symptoms of the disease or disorder. These infectious diseases include viral infections, particularly HCV infections. The invention is particularly includes methods of treating human patients suffering from an infectious disease, but also encompasses methods of treating other animals, including livestock and domesticated companion animals, suffering from an infectious disease. Methods of treatment include administering a compound of Formula I as a single active agent or administering a compound of Formula I in combination with on or more other therapeutic agent.

Substituted Arylthiourea Derivatives Useful As Inhibitors Of Viral Replication

US Patent:
7718671, May 18, 2010
Filed:
Jul 8, 2004
Appl. No.:
10/887227
Inventors:
Avinash Phadke - Branford CT, US
Jesse Quinn - Windsor CT, US
Junko Ohkanda - Gakuennishi, JP
Andrew Thurkauf - Ridgefield CT, US
Yiping Shen - Branford CT, US
Cuixian Liu - Branford CT, US
Dawei Chen - Middletown CT, US
Shouming Li - Cheshire CT, US
Xiangzhu Wang - Branford CT, US
Assignee:
Achillion Pharmaceuticals, Inc. - New Haven CT
International Classification:
A61K 31/47
C07D 217/02
A61K 31/445
C07D 211/32
C07C 335/00
US Classification:
514307, 546144, 546233, 514331, 564 27
Abstract:
Substituted arylthiourea compounds of Formula I,.

Substituted Aryl Acylthioureas And Related Compounds; Inhibitors Of Viral Replication

US Patent:
7767706, Aug 3, 2010
Filed:
Feb 25, 2008
Appl. No.:
12/036728
Inventors:
Avinash Phadke - Branford CT, US
Dawei Chen - Middletown CT, US
Milind Deshpande - Madison CT, US
Andrew Thurkauf - Ridgefield CT, US
Xiangzhu Wang - Branford CT, US
Yiping Shen - Branford CT, US
Cuixian Liu - Branford CT, US
Jesse Quinn - Windsor CT, US
Junko Ohkanda - Osaka, JP
Shouming Li - Cheshire CT, US
Assignee:
Achillion Pharmaceuticals, Inc. - New Haven CT
International Classification:
A61K 31/415
C07D 231/10
US Classification:
514406, 5483741
Abstract:
The invention provides compounds and pharmaceutically acceptable salts of Formula IThe invention further comprises methods of treating patients suffering from certain infectious diseases by administering to such patients an amount of a compound of Formula I effective to reduce signs or symptoms of the disease or disorder. These infectious diseases include viral infections, particularly HCV infections. The invention is particularly includes methods of treating human patients suffering from an infectious disease, but also encompasses methods of treating other animals, including livestock and domesticated companion animals, suffering from an infectious disease. Methods of treatment include administering a compound of Formula I as a single active agent or administering a compound of Formula I in combination with on or more other therapeutic agent.

Thiazole Compounds And Methods Of Use

US Patent:
8088806, Jan 3, 2012
Filed:
May 9, 2006
Appl. No.:
11/431155
Inventors:
Suoming Zhang - Madison CT, US
Avinash Phadke - Branford CT, US
Cuixian Liu - Madison CT, US
Xiangzhu Wang - Branford CT, US
Jesse Quinn - Windsor CT, US
Dawei Chen - Middletown CT, US
Venkat Gadhachanda - Hamden CT, US
Shouming Li - Chesire CT, US
Milind Deshpande - Madison CT, US
Assignee:
Achillion Pharmaceuticals, Inc. - New Haven CT
International Classification:
A61K 31/426
A61K 31/44
US Classification:
514370, 514342
Abstract:
The present invention provides compounds, salts and hydrates of Formula I,.

Urea-Containing Peptides As Inhibitors Of Viral Replication

US Patent:
8163693, Apr 24, 2012
Filed:
Sep 24, 2008
Appl. No.:
12/236855
Inventors:
Dawei Chen - Middletown CT, US
Milind Deshpande - Madison CT, US
Avinash Phadke - Branford CT, US
Assignee:
Achillion Pharmaceuticals, Inc. - New Haven CT
International Classification:
A61K 38/00
US Classification:
514 37
Abstract:
The invention provides compounds urea-containing peptide compounds of Formula IThe variables T, R-R, J, L, M, Y, Z, m, n, and t are defined herein. Certain compounds of Formula I are useful as antiviral agents. Certain urea-containing peptide compounds disclosed herein are potent and/or selective inhibitors of viral replication, particularly Hepatitis C virus replication. The invention also provides pharmaceutical compositions containing one or more urea containing peptides compounds and one or more pharmaceutically acceptable carriers, excipients, or diluents. Such pharmaceutical compositions may contain a urea containing peptides compound as the only active agent or may contain a combination of a urea containing peptides compound and one or more other pharmaceutically active agents. The invention also provides methods for treating viral infections, including Hepatitis C infections, in mammals.

Possible Relatives

Cynthia Chen  David Chen  Cyril X Chen  Cyrus Y Chen  De T Chen  Dafang Chen  Dagang Chen  Dawei Li  Dawei N Wei  Dawei H Xu 

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