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Dawoon Jung, 4514738 Ash Ave, Flushing, NY 11355

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14738 Ash Ave, Flushing, NY 11355    347-3684387   

Buffalo Grove, IL   

Brooklyn, NY   

West Lafayette, IN   

W Lafayette, IN   

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Us Patents

Modulators Of Hepatocyte Growth Factor/C-Met Activity

US Patent:
2007021, Sep 13, 2007
Filed:
Jan 10, 2007
Appl. No.:
11/651927
Inventors:
David Zembower - La Grange IL, US
Jasbir Singh - Naperville IL, US
Rama Mishra - Chicago IL, US
Dawoon Jung - Tenafly NJ, US
Xiaokang Zhu - Hempstead NY, US
Assignee:
Angion Biomedica Corporation - Manhasset NY
International Classification:
A61K 31/55
A61K 31/5377
A61K 31/517
C07D 413/02
C07D 405/02
C07D 403/02
US Classification:
514217060, 514266400, 514266240, 544284000, 544291000, 514266220, 514234200, 544114000, 514266200, 514252170, 540600000
Abstract:
This invention is directed to compounds and compositions that have biological properties useful for modulating HGF/SF activity. In certain embodiments, said compounds and compositions may be used in the treatment and prophylaxis of cancer or other dysproliferative diseases, as well as inflammatory diseases such as rheumatoid arthritis.

Modulators Of Hepatocyte Growth Factor/C-Met Activity

US Patent:
2008005, Mar 6, 2008
Filed:
Jan 10, 2007
Appl. No.:
11/651926
Inventors:
David Zembower - La Grange IL, US
Jasbir Singh - Naperville IL, US
Rama Mishra - Chicago IL, US
Dawoon Jung - Tenafly NJ, US
Xiaokang Zhu - Hempstead NY, US
Assignee:
Angion Biomedica Corporation - Manhasset NY
International Classification:
A61K 31/517
A61K 31/496
A61K 31/5377
A61K 31/541
A61K 31/55
A61P 19/02
A61P 35/00
US Classification:
514217060, 514228200, 514234500, 514252170, 514266220, 514266400
Abstract:
This invention is directed to compounds and compositions that have biological properties useful for modulating HGF/SF activity. In certain embodiments, said compounds and compositions may be used in the treatment and prophylaxis of cancer or other dysproliferative diseases and inflammatory diseases such as rheumatoid arthritis.

Ethynylheterocycles As Rho-Associated Coiled-Coil Kinase (Rock) Inhibitors

US Patent:
2022028, Sep 8, 2022
Filed:
Jul 21, 2020
Appl. No.:
17/629061
Inventors:
- Uniondale NY, US
Satish Kumar Sakilam - Harrison NJ, US
Satishkumar Gadhiya - Jamaica NY, US
Dong Sung Lim - Fair Lawn NJ, US
Yao Zong - Port Washington NY, US
Shashikanth Ponnala - Secaucus NJ, US
Ying Zhang - Glen Cove NY, US
Dawoon Jung - Tenafly NJ, US
Lambertus J.W.M. Oehlen - Westbury NY, US
International Classification:
C07D 401/14
C07D 403/14
C07D 471/04
C07D 487/04
C07D 417/14
C07F 9/6558
Abstract:
The present invention provides compounds having formula (I): and pharmaceutically acceptable salts thereof, wherein Cy1, Cy2, Cy3, R, R, R, and Rare as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases in which inhibiting ROCK1, ROCK2, or ROCK1/2 has a therapeutically useful role.

Vinylheterocycles As Rho-Associated Coiled-Coil Kinase (Rock) Inhibitors

US Patent:
2020023, Jul 23, 2020
Filed:
Aug 31, 2018
Appl. No.:
16/643805
Inventors:
- Uniondale NY, US
Dibyendu Dana - Elmont NY, US
Dong Sung Lim - Fair Lawn NJ, US
Satishkumar Gadhiya - Jamaica NY, US
Dawoon Jung - Tenafly NJ, US
Prakash Narayan - East Northport NY, US
Quaisar Ali - Franklin Square NY, US
Latha Paka - Elmont NY, US
Itzhak D. Goldberg - Englewood NJ, US
International Classification:
C07D 403/14
C07D 401/14
Abstract:
The present invention provides compounds having formula (I): and pharmaceutically acceptable salts thereof, wherein Cy1, Cy2, Cy3, R, R, R, R, Aand Aare as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases in which inhibiting ROCK1, ROCK2, or ROCK1/2 has a therapeutically useful role.

Antifibrotic Compounds And Uses Thereof

US Patent:
2020006, Mar 5, 2020
Filed:
Aug 2, 2019
Appl. No.:
16/530688
Inventors:
- Uniondale NY, US
Rama K. MISHRA - Chicago IL, US
Dong Sung LIM - Fair Lawn NJ, US
Lambertus J.W.M. OEHLEN - Westbury NY, US
Dawoon JUNG - Tenafly NJ, US
Assignee:
ANGION BIOMEDICA CORP. - Uniondale NY
International Classification:
A61K 31/437
A61K 31/4353
C07D 401/14
C07D 401/02
C07D 471/04
A61K 31/496
A61K 31/5377
Abstract:
The present invention provides compounds having the general structural formula (I)and pharmaceutically acceptable derivatives thereof, as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases involving abnormal or excessive fibrosis.

Antifibrotic Compounds And Uses Thereof

US Patent:
2019012, May 2, 2019
Filed:
Dec 18, 2018
Appl. No.:
16/224442
Inventors:
- Uniondale NY, US
Rama K. MISHRA - Chicago IL, US
Dong Sung LIM - Fair Lawn NJ, US
Lambertus J.W.M. OEHLEN - Westbury NY, US
Dawoon JUNG - Tenafly NJ, US
Assignee:
ANGION BIOMEDICA CORP. - Uniondale NY
International Classification:
A61K 31/437
A61K 31/5377
A61K 31/496
Abstract:
The present invention provides compounds having the general structural formula (I)and pharmaceutically acceptable derivatives thereof, as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases involving abnormal or excessive fibrosis.

Cytochrome P450 Inhibitors And Uses Thereof

US Patent:
2018014, May 31, 2018
Filed:
Nov 29, 2016
Appl. No.:
15/364211
Inventors:
- Uniondale NY, US
Dong Sung Lim - Fair Lawn NJ, US
Rama K. Mishra - Chicago IL, US
Lambertus J.W.M. Oehlen - Westbury NY, US
James G. Tarrant - Searcy AR, US
Xiaokang Zhu - Oakland Gardens NY, US
Dawoon Jung - Tenafly NJ, US
Assignee:
Angion Biomedica Corp - Uniondale NY
International Classification:
C07D 417/06
Abstract:
The present invention provides compounds having the general structural formula (I)and pharmaceutically acceptable derivatives thereof, as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases involving fibrosis and proliferation, and where anti-fibrotic or anti-proliferative activity is beneficial.

Relaxin-Like Peptides And Uses Thereof

US Patent:
2016006, Mar 3, 2016
Filed:
Sep 10, 2013
Appl. No.:
14/427132
Inventors:
- Garden City NY, US
Itzhak D. Goldberg - Englewood NJ, US
Rama K. Mishra - Chicago IL, US
E. Siobhan McCormack - Glen Head NY, US
Dawoon Jung - Tenafly NJ, US
Assignee:
ANGION BIOMEDICA CORP. - Uniondale NY
International Classification:
C07K 14/64
Abstract:
The present invention is directed to novel peptides that exhibit relaxin activity, and uses thereof for treating diseases such as heart failure and liver, lung, cardiac or kidney fibrosis.

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