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Dennis Stanley France, 6968 Powers Rd, Graniteville, MA 01886

Dennis France Phones & Addresses

68 Powers Rd, Westford, MA 01886    973-2923866   

Groton, MA   

33 Spruce St, Winchester, MA 01890    781-3691789   

289 Pearl St, Cambridge, MA 02139   

291 Pearl St, Cambridge, MA 02139   

Morris Plains, NJ   

Dorchester, MA   

Montclair, NJ   

Brooklyn, NY   

10 Robin Hill Rd, Groton, MA 01450   

Work

Position: Professional/Technical

Education

Degree: Graduate or professional degree

Mentions for Dennis Stanley France

Dennis France resumes & CV records

Resumes

Dennis France Photo 33

Vice President

Location:
Westford, MA
Work:
Horizon Discovery
Vice President
Dennis France Photo 34

Dennis France

Dennis France Photo 35

Dennis France

Dennis France Photo 36

Dennis France - Groton, MA

Work:
Denirus Life Science Consulting May 2012 to 2000
Principal Consultant
Forma Therapeutics Inc - Watertown, MA 2011 to 2012
Executive Director and Head, Biomolecular Screening
ArQule, Inc - Woburn, MA 2007 to 2011
Vice President, Biomolecular Discovery
Vice President, Oncology Lead Discovery 2004 to 2007 Novartis Institutes for BioMedical Research Inc - Summit, NJ 2002 to 2004
Executive Director, Oncology Disease Area
Novartis Pharmaceuticals, Inc - Summit, NJ 1994 to 2002
Senior Scientist/Program Team Head, Department of Oncology Research
Alteon, Inc - Ramsey, NJ 1993 to 1994
Director, Exploratory Research
Sandoz Research Institute - East Hanover, NJ 1992 to 1993
Senior Scientist B, Department of Atherosclerosis & Vascular Biology
Department of Lipids & Lipoprotein Metabolism 1987 to 1992
Scientist/Senior Scientist
The Mount Sinai School of Medicine - New York, NY 1983 to 1986
Research Coordinator, Division of Arteriosclerosis & Metabolism
The Mount Sinai School of Medicine 1985 to 1985 The Mount Sinai School of Medicine - New York, NY 1980 to 1983
Technical Supervisor, Department of Dermatology
The New York University Medical Center - New York, NY 1978 to 1980
Dermatology Research Assistant, Department of Dermatology
Harvard Medical School, Brigham/Dana Farber Cancer Center - Boston, MA 1975 to 1976
Research Hematology Technician, Department of Hematology
Education:
Babson College Executive Education 2009
Business of Science
the Center for Creative 2007
Leadership Development Program
Vassar College - Poughkeepsie, NY 1972 to 1977
B.A. in Biology/Psychology
Dennis France Photo 37

Dennis France - Groton, MA

Work:
Denirus Consulting LLC May 2012 to 2000
Founder & President
Forma Therapeutics Inc - Watertown, MA Dec 2011 to May 2012
Executive Director & Head, Biomolecular Screening
ArQule, Inc - Woburn, MA Feb 2007 to Dec 2011
Vice President, Biomolecular Discovery
ArQule, Inc. - Woburn, MA Jul 2004 to Jan 2007
Vice President, Oncology Lead Discovery
Novartis Institutes for BioMedical Research Inc - Summit, NJ Jul 2002 to Jul 2004
Executive Director, Oncology Disease Area
Novartis Pharmaceuticals, Inc - Summit, NJ Mar 2001 to Jul 2002
Program Team Head "New Drug Discovery Technologies"
Department of Oncology Research Jul 1994 to Mar 2001
Senior Scientist III
Alteon, Inc - Ramsey, NJ Jul 1993 to Jul 1994
Director, Exploratory Research
Sandoz Research Institute - East Hanover, NJ Jan 1992 to Jul 1993
Senior Scientist B, Department of Atherosclerosis & Vascular Biology
Department of Lipids & Lipoprotein Metabolism Jan 1989 to Dec 1991
Senior Scientist
Department of Lipids & Lipoprotein Metabolism Jan 1987 to Dec 1988
Scientist B
The Mount Sinai School of Medicine - New York, NY Aug 1983 to Dec 1986
Research Coordinator, Division of Arteriosclerosis & Metabolism
The Mount Sinai School of Medicine - New York, NY Mar 1980 to Jul 1983
Technical Supervisor, Department of Dermatology
The New York University Medical Center - New York, NY Jan 1978 to Feb 1980
Dermatology Research Assistant, Department of Dermatology
Harvard Medical School - Boston, MA May 1975 to Aug 1976
Research Hematology Technician, Department of Hematology
Education:
Vassar College - Poughkeepsie, NY 1977
B.A. in Biology/Psychology
The Center for Creative Leadership
Leadership Development Program
Babson College Executive Education
Business of Science

Publications & IP owners

Us Patents

Raf Inhibitors And Their Uses

US Patent:
7501430, Mar 10, 2009
Filed:
Apr 16, 2007
Appl. No.:
11/785163
Inventors:
Jean-Marc Lapierre - Pelham NH, US
Nivedita D. Namdev - Westford MA, US
Mark A. Ashwell - Carlisle MA, US
Dennis S. France - Carlisle MA, US
Hui Wu - Malden MA, US
Patrick M. Hutchins - Denver CO, US
Manish Tandon - Framingham MA, US
Yanbin Liu - Acton MA, US
Jeff S. Link - Londonderry NH, US
Syed M. Ali - North Andover MA, US
Chris J. Brassard - Somerville MA, US
Robb B. Nicewonger - Tyngsboro MA, US
Anton Filikov - Stoneham MA, US
Rebecca J. Carazza - Winchester MA, US
Assignee:
ArQule, Inc. - Woburn MA
International Classification:
C07D 498/04
C07D 513/04
A61K 31/429
A61K 31/4188
US Classification:
514275, 544333
Abstract:
The present invention provides imidazooxazole and imidazothiazole compounds and their synthesis. The compounds of the present invention are capable of inhibiting the activity of RAF kinase, such as B-RAF. The compounds are useful for the treatment of cell proliferative disorders such as cancer.

Combinational Compositions And Methods For Treatment Of Cancer

US Patent:
8580764, Nov 12, 2013
Filed:
Jul 1, 2011
Appl. No.:
13/174890
Inventors:
Giovanni Abbadessa - Boston MA, US
Dennis S. France - Winchester MA, US
Thomas C. K. Chan - Winchester MA, US
Assignee:
ArQule, Inc. - Woburn MA
International Classification:
A01N 43/04
A61K 31/70
A01N 43/62
A61K 31/55
A61K 31/535
A01N 43/42
A61K 31/44
US Classification:
514 49, 514220, 5142335, 514294
Abstract:
The present invention provides methods of treating a cell proliferative disorder, such as lung cancer and breast cancer, by administering to a subject in need thereof a therapeutically effective amount of a pyrroloquinolinyl-pyrrole-2,5-dione compound or a pyrroloquinolinyl-pyrrolidine-2,5-dione compound, such as (−)-trans-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione, in combination with a therapeutically effective amount of a second anti-proliferative agent, such as gemcitabine.

Raf Inhibitors And Uses Thereof

US Patent:
2009013, May 28, 2009
Filed:
Jan 20, 2009
Appl. No.:
12/356097
Inventors:
Jean-Marc Lapierre - Pelham NH, US
Nivedita D. Namdev - Westford MA, US
Mark A. Ashwell - Carlisle MA, US
Dennis S. France - Cambridge MA, US
Hui Wu - Malden MA, US
Patrick M. Hutchins - Denver CO, US
Manish Tandon - Framingham MA, US
Yanbin Liu - Acton MA, US
Jeff S. Link - Londonderry NH, US
Syed M. Ali - North Andover MA, US
Chris J. Brassard - Somerville MA, US
Robb B. Nicewonger - Tyngsboro MA, US
Anton Filikov - Stoneham MA, US
Rebecca J. Carazza - Winchester MA, US
Assignee:
ARQULE, INC. - Woburn MA
International Classification:
A61K 39/395
C07D 513/04
A61K 31/506
A61K 31/5377
C07D 498/04
A61P 35/00
US Classification:
4241331, 544331, 514275, 5142332, 544122, 51421021
Abstract:
The present invention provides imidazooxazole and imidazothiazole compounds and their synthesis. The compounds of the present invention are capable of inhibiting the activity of RAF kinase, such as B-RAF. The compounds are useful for the treatment of cell proliferative disorders such as cancer.

Combinational Compositions And Methods For Treatment Of Cancer

US Patent:
2010029, Nov 25, 2010
Filed:
Feb 11, 2010
Appl. No.:
12/704361
Inventors:
Thomas C.K. Chan - Winchester MA, US
Dennis S. France - Winchester MA, US
Kenichi Ishii - Shizuoka, JP
Paolo Pucci - Westport CT, US
Assignee:
ArQule, Inc. - Woburn MA
Kyowa Hakko Kirin Co., Ltd. - Tokyo
International Classification:
A61K 38/21
A61K 39/395
A61K 38/22
A61K 33/24
A61P 35/00
A61P 35/04
A61P 35/02
A61K 31/4745
A61K 31/517
A61K 31/506
A61K 31/5377
A61K 31/7068
A61K 31/513
US Classification:
424 854, 4241411, 4241301, 514 97, 424649, 514294, 5142664, 51425218, 5142345, 514 49, 514274, 514283
Abstract:
The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a pyrroloquinolinyl-pyrrole-2,5-dione compound or a pyrroloquinolinyl-pyrrolidine-2,5-dione compound in combination with a therapeutically effective amount of a second anti-proliferative agent.

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