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Dimitri S Pappas, 473707 67Th St, Lubbock, TX 79413

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3707 67Th St, Lubbock, TX 79413    806-3922024   

4105 62Nd St, Lubbock, TX 79413    806-3688265   

2105 Royal Oaks Dr, League City, TX 77573    281-5380190   

3826 30Th St, Gainesville, FL 32608    352-3719227   

Seabrook, TX   

Ormond Beach, FL   

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Us Patents

Microdevice For Cell Separation Utilizing Activation Phenotype

US Patent:
2017030, Oct 26, 2017
Filed:
Oct 9, 2015
Appl. No.:
15/517921
Inventors:
- Lubbock TX, US
Dimitri PAPPAS - Lubbock TX, US
Assignee:
Texas Tech University System - Lubbock TX
International Classification:
G01N 33/569
G01N 33/543
B01L 3/00
G01N 33/00
C12Q 1/00
Abstract:
Disclosed is a system and method for a microdevice to separate blood cells based on differences in antigen expression. Specifically, cells of the same phenotype are separated based on whether or not they are activated during infection or resting. The device of the present disclosure takes a small sample of blood and provides differential cell counts that can be used to test for infection and inflammatory response. The device can be used to identify sepsis and other infections rapidly. By measuring differences in activated white cell counts such as neutrophils, the device of the present disclosure measures physiological response to infection in hospitalized patients recovering from burns, surgeries, etc.

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