Douglas Hecker resumes & CV records
Resumes
Douglas Hecker
Douglas B Hecker, 571833 Welleslay Ct, Liberty, MO 64068
Douglas Hecker Phones & Addresses
1833 Welleslay Ct, Liberty, MO 64068 816-7813518
420 N La Frenz Rd, Liberty, MO 64068
Pleasant Valley, MO
Columbia, MO
Hannibal, MO
McPherson, KS
Mentions for Douglas B Hecker
Publications & IP owners
Us Patents
Sulfoalkyl Ether Cyclodextrin Compositions And Methods Of Preparation Thereof
US Patent:
8049003, Nov 1, 2011
Filed:
Apr 23, 2008
Appl. No.:
12/108228
Inventors:
Gerold L. Mosher - Kansas City MO, US
James D. Pipkin - Lawrence KS, US
Douglas B. Hecker - Liberty MO, US
James D. Pipkin - Lawrence KS, US
Douglas B. Hecker - Liberty MO, US
Assignee:
CyDex Pharmaceuticals, Inc. - Lenexa KS
International Classification:
C08B 37/16
C07H 3/06
C07H 15/04
A61K 31/716
A61K 31/718
A61K 31/702
C07H 3/06
C07H 15/04
A61K 31/716
A61K 31/718
A61K 31/702
US Classification:
536103, 514 54, 514 58, 536111, 536120, 53612312
Abstract:
A particulate SAE-CD composition is provided. The SAE-CD composition has an advantageous combination of physical properties not found in known solid forms of SAE-CD. In particular, the SAE-CD composition possesses an advantageous physicochemical and morphological property profile such that it can be tailored to particular uses. The SAE-CD composition of the invention has improved flow and dissolution performance as compared to known compositions of SAE-CD.
Dpi Formulation Containing Sulfoalkyl Ether Cyclodextrin
US Patent:
8114438, Feb 14, 2012
Filed:
Oct 19, 2006
Appl. No.:
11/550976
Inventors:
James D. Pipkin - Lawrence KS, US
Gerold L. Mosher - Kansas City MO, US
Douglas B. Hecker - Liberty MO, US
Gerold L. Mosher - Kansas City MO, US
Douglas B. Hecker - Liberty MO, US
Assignee:
Cydex Pharmaceuticals, Inc. - Lenexa KS
International Classification:
A61K 9/00
A61K 9/14
A61K 9/16
A61K 9/14
A61K 9/16
US Classification:
424489, 424 46
Abstract:
An inhalable dry powder formulation containing SAE-CD and an active agent is provided. The formulation is adapted for administration by DPI. The SAE-CD serves as a carrier rather than as an absorption enhancer. The average particle size of the SAE-CD is large enough to preclude (for the most part) pulmonary deposition thereof. Following release from the DPI device, the SAE-CD-containing particles dissociate from the active agent-containing particles in the buccal cavity or throat, after which the active agent-containing particles continue deeper into the respiratory tract. The physicochemical and morphological properties of the SAE-CD are easily modified to permit optimization of active agent and carrier interactions. Drugs having a positive, neutral or negative electrostatic charge can be delivered by DPI when SAE-CD is used as a carrier.
Sulfoalkyl Ether Cyclodextrin Compositions And Methods Of Preparation Thereof
US Patent:
2009012, May 14, 2009
Filed:
Jan 31, 2009
Appl. No.:
12/363719
Inventors:
James D. PIPKIN - Lawrence KS, US
Gerold L. MOSHER - Kansas City MO, US
Douglas B. HECKER - Liberty MO, US
Gerold L. MOSHER - Kansas City MO, US
Douglas B. HECKER - Liberty MO, US
Assignee:
CyDex Pharmaceuticals, Inc. - Lenexa KS
International Classification:
A61K 47/40
A61K 9/14
A61K 9/20
A61K 9/14
A61K 9/20
US Classification:
424468, 514777, 424499, 424464
Abstract:
A particulate SAE-CD composition is provided. The SAE-CD composition has an advantageous combination of physical properties not found in known solid forms of SAECD. In particular, the SAE-CD composition possesses an advantageous physicochemical and morphological property profile such that it can be tailored to particular uses. The SAE-CD composition of the invention has improved flow and dissolution performance as compared to known compositions of SAE-CD.
Sulfoalkyl Ether Cyclodextrin Compositions And Methods Of Preparation Thereof
US Patent:
2012013, May 31, 2012
Filed:
Sep 23, 2011
Appl. No.:
13/243956
Inventors:
Gerold L. Mosher - Kansas City MO, US
James D. Pipkin - Lawrence KS, US
Douglas B. Hecker - Liberty MO, US
James D. Pipkin - Lawrence KS, US
Douglas B. Hecker - Liberty MO, US
International Classification:
A61K 47/40
B32B 5/16
C08B 37/16
B32B 5/16
C08B 37/16
US Classification:
514778, 536103, 428402
Abstract:
A particulate SAE-CD composition is provided. The SAE-CD composition has an advantageous combination of physical properties not found in known solid forms of SAE-CD. In particular, the SAE-CD composition possesses an advantageous physicochemical and morphological property profile such that it can be tailored to particular uses. The SAE-CD composition of the invention has improved flow and dissolution performance as compared to known compositions of SAE-CD.
Dpi Formulation Containing Sulfoalkyl Ether Cyclodextrin
US Patent:
2012016, Jun 28, 2012
Filed:
Dec 22, 2011
Appl. No.:
13/335780
Inventors:
James D. Pipkin - Lawrence KS, US
Gerold L. Mosher - Kansas City MO, US
Douglas B. Hecker - Liberty MO, US
Gerold L. Mosher - Kansas City MO, US
Douglas B. Hecker - Liberty MO, US
Assignee:
CyDex Pharmaceuticals, Inc. - Lenexa KS
International Classification:
A61K 9/16
A61P 29/00
B32B 5/16
A61P 11/00
A61P 29/00
B32B 5/16
A61P 11/00
US Classification:
424400, 428402
Abstract:
An inhalable dry powder formulation containing SAE-CD and an active agent is provided. The formulation is adapted for administration by DPI. The SAE-CD serves as a carrier rather than as an absorption enhancer. The average particle size of the SAE-CD is large enough to preclude (for the most part) pulmonary deposition thereof. Following release from the DPI device, the SAE-CD-containing particles dissociate from the active agent-containing particles in the buccal cavity or throat, after which the active agent-containing particles continue deeper into the respiratory tract. The physicochemical and morphological properties of the SAE-CD are easily modified to permit optimization of active agent and carrier interactions. Drugs having a positive, neutral or negative electrostatic charge can be delivered by DPI when SAE-CD is used as a carrier.
Dpi Formulation Containing Sulfoalkyl Ether Cyclodextrin
US Patent:
2013019, Aug 1, 2013
Filed:
Mar 11, 2013
Appl. No.:
13/794652
Inventors:
Gerold L. Mosher - Kansas City MO, US
Douglas B. Hecker - Liberty MO, US
Douglas B. Hecker - Liberty MO, US
Assignee:
CyDex Pharmaceuticals, Inc. - La Jolla CA
International Classification:
A61K 47/40
US Classification:
514778, 536103, 428402
Abstract:
An inhalable dry powder formulation containing SAE-CD and an active agent is provided. The formulation is adapted for administration by DPI. The SAE-CD serves as a carrier rather than as an absorption enhancer. The average particle size of the SAE-CD is large enough to preclude (for the most part) pulmonary deposition thereof. Following release from the DPI device, the SAE-CD-containing particles dissociate from the active agent-containing particles in the buccal cavity or throat, after which the active agent-containing particles continue deeper into the respiratory tract. The physicochemical and morphological properties of the SAE-CD are easily modified to permit optimization of active agent and carrier interactions. Drugs having a positive, neutral or negative electrostatic charge can be delivered by DPI when SAE-CD is used as a carrier.
Sulfoalkyl Ether Cyclodextrin Compositions And Methods Of Preparation Thereof
US Patent:
2013028, Oct 31, 2013
Filed:
Mar 11, 2013
Appl. No.:
13/794677
Inventors:
Gerold L. Mosher - Kansas City MO, US
Douglas B. Hecker - Liberty MO, US
Douglas B. Hecker - Liberty MO, US
International Classification:
C08B 37/16
US Classification:
428402, 536103
Abstract:
A particulate SAE-CD composition is provided. The SAE-CD composition has an advantageous combination of physical properties not found in known solid forms of SAE-CD. In particular, the SAE-CD composition possesses an advantageous physicochemical and morphological property profile such that it can be tailored to particular uses. The SAE-CD composition of the invention has improved flow and dissolution performance as compared to known compositions of SAE-CD.
Dpi Formulation Containing Sulfoalkyl Ether Cyclodextrin
US Patent:
2020027, Sep 3, 2020
Filed:
May 15, 2020
Appl. No.:
16/875855
Inventors:
- San Diego CA, US
Gerold L. Mosher - Kansas City MO, US
Douglas B. Hecker - Liberty MO, US
Gerold L. Mosher - Kansas City MO, US
Douglas B. Hecker - Liberty MO, US
International Classification:
A61K 47/40
A61K 9/00
A61K 9/00
Abstract:
An inhalable dry powder formulation containing SAE-CD and an active agent is provided. The formulation is adapted for administration by DPI. The SAE-CD serves as a carrier rather than as an absorption enhancer. The average particle size of the SAE-CD is large enough to preclude (for the most part) pulmonary deposition thereof. Following release from the DPI device, the SAE-CD-containing particles dissociate from the active agent-containing particles in the buccal cavity or throat, after which the active agent-containing particles continue deeper into the respiratory tract. The physicochemical and morphological properties of the SAE-CD are easily modified to permit optimization of active agent and carrier interactions. Drugs having a positive, neutral or negative electrostatic charge can be delivered by DPI when SAE-CD is used as a carrier.
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