Edgar C Cohen Deceased4123 Vincennes Pl, New Orleans, LA 70125

6568398, May 27, 2003

Mar 7, 2001

09/799693

Edgar C Cohen - New Orleans LA

Edgar C. Cohen - New Orleans LA

A61B 1900

128898, 424499, 424435, 42840224, 264 4

This invention relates to hemostatic therapeutic compositions and, more particularly to methods for bringing about rapid, painless hemostasis intraorally, for dermatological applications or all other hemostasis applications. 100 to 300 micron microcapsules comprising a granular astringent hemostatic agent micro-encapsulated with a biocompatible polymer are applied to a wound. The microcapsules are applied to the wound until the outermost layer of microcapsules remain white, a visible indication that the hemostatic action is complete. Upon observation that the hemostatic action is complete the microcapsules are flushed from the wound, the wound blotted and dressed. The rapid clotting times achieved with the 100 to 300 micron size microcapsules together with the visual indication that hemostasis is complete gives the practitioner the ability to irrigate the wound and apply a protective dressing much more quickly than the prior art and excess microcapsules are not wasted.

4597960, Jul 1, 1986

Jun 3, 1983

6/500689

Edgar C. Cohen - New Orleans LA

A61K 3306
A61K 3326
A01N 5906
A01N 5916

424 28

An astringent hemostatic composition comprised of a micron-sized astringent hemostatic agent microencapsulated in a biocompatible and non-allergenic hemostatic polymer soluble in body fluids. The composition may be used intraorally or dermatologically. For intraoral purposes, the preferred composition is ferric sulfate microencapsulated in ethyl cellulose material. The composition of the invention may be used in a method for effecting gingival retraction. In the method, the microencapsulated astringent hemostatic composition is introduced into the gingival sulcus and is compacted by the patient biting onto bite registration material. A plurality of different microencapsulated astringent hemostatic agents having different time-release properties may be assembled in a kit form allowing a practitioner to formulate a specific formulation designed to treat a specific injury or condition. An astringent hemostatic composition of the invention may be used in a bandage for covering a wound. In one bandage embodiment, the gauze or sponge pad is sprayed with a biocompatible adhesive onto which a dusting of astringent hemostatic composition of the invention is applied.

4403609, Sep 13, 1983

Feb 24, 1981

6/237563

Edgar C. Cohen - New Orleans LA

A61M 530

604 70

A needless vacuum-compression injector stabilizes a nozzle over the tissue to be penetrated by means of a continuous vacuum applied to an annular area surrounding the point of penetration. The vacuum draws the tissue toward the annular region and immobilizes the tissue over the nozzle without puncturing the tissue and without substantially displacing the tissue from its initial condition. Pressurized gas is used to express a medicament through an orifice in the nozzle and into the immobilized tissue.

4421508, Dec 20, 1983

Jul 8, 1981

6/281436

Edgar C. Cohen - New Orleans LA

A61M 530

604 70

A needleless vacuum-compression injector applies a continuous vacuum between a medicament holder and an outwardly extending member spaced therefrom. The continuous vacuum holds tissue taut and immobilizes the tissue over a nozzle without puncturing the tissue. Pressurized gas then injects the medicament into the tissue to a predetermined depth determined by the pressure of the gas. The outwardly extending member can be a removable sleeve. Particularly for oral applications, the tissue-engaging surface of the outwardly extending member can be oval or otherwise non-circular in shape to accommodate the shape of the tissue to be injected.