Edward M Cohen Deceased6003 Gloster Rd, Bethesda, MD 20816

8288322, Oct 16, 2012

Oct 25, 2001

10/045674

Robert C. Ladner - Ijamsville MD, US
Edward H. Cohen - Belmont MA, US
Horacio G. Nastri - Newton MA, US
Kristin L. Rookey - Revere MA, US
Rene Hoet - Maastricht, NL
Hendricus Renerus Jacobus Mattheus Hoogenboom - Maastricht, NL

Dyax Corp. - Burlington MA

C12Q 1/68
C12P 19/34

506 18, 435 61, 435 618, 435 912

A library containing a collection of genetic packages that display a member of a diverse family of peptides, polypeptides or proteins and that collectively display at least a portion of the family, the displayed peptides, polypeptides or proteins being encoded by DNA sequences containing sequences encoding a heavy chain CDR region is described.

2004002, Feb 12, 2004

Apr 17, 2001

09/837306

Robert Ladner - Ijamsville MD, US
Edward Cohen - Belmont MA, US
Horacio Nastri - Newton MA, US
Kristin Rookey - Revere MA, US
Rene Hoet - Maastricht, NL

C12Q001/68
C12P019/34

435/006000, 435/091200

The present invention relates to constructing libraries of genetic packages that display a member of a diverse family of peptides, polypeptides or proteins and collectively display at least a portion of the diversity of the family. In a preferred embodiment, the displayed polypeptides are human Fabs. More specifically, the invention is directed to the methods of cleaving single-stranded nucleic acids at chosen locations, the cleaved nucleic acids encoding, at least in part, the peptides, polypeptides or proteins displayed on the genetic packages of the libraries of the invention. In a preferred embodiment, the genetic packages are filamentous phage or phagemids. The present invention further relates to methods of screening the libraries of genetic packages that display useful peptides, polypeptides and proteins and to the peptides, polypeptides and proteins identified by such screening.

2006016, Jul 27, 2006

Feb 28, 2006

11/365556

Robert Ladner - Ijamsville MD, US
Edward Cohen - Belmont MA, US
Horacio Nastri - Newton MA, US
Kristin Rookey - Revere MA, US
Rene Hoet - Maastricht, NL

C40B 40/08
C40B 40/10

435006000

Methods useful in constructing libraries that collectively display members of diverse families of peptides, polypeptides or proteins and the libraries produced using those methods. Methods of screening those libraries and the peptides, polypeptides or proteins identified by such screens.

2013004, Feb 14, 2013

May 4, 2012

13/464047

Robert C. Ladner - Ijamsville MD, US
Edward H. Cohen - Belmont MA, US
Horacio G. Nastri - Newton MA, US
Kristin L. Rookey - Revere MA, US
Rene Hoet - Maastricht, NL
Hendricus Renerus Jacobus Mattheus Hoogenboom - Maastricht, NL

DYAX CORP. - Burlington MA

C40B 50/06
C40B 40/10
C12N 15/63
C12P 19/34

506 18, 435 9153, 506 26, 4353201, 435 912

Methods useful in constructing libraries that collectively display and/or express members of diverse families of peptides, polypeptides or proteins and the libraries produced using those methods are disclose. Methods of screening those libraries and the peptides, polypeptides or proteins identified by such screens are also disclosed.

3949947, Apr 13, 1976

Sep 23, 1974

5/508560

Robertson Youngquist - Kensington MD
Donald Green - Washington DC
Edward Stone Cohen - Washington DC

New World Container Corporation - Washington DC

B65H 1900

242 5553

A dispensing device for a paper web adapted to be carried in a pocket, purse or the like for holding a supply of paper and enabling a desired quantity of such paper to be readily dispensed. The paper may be that type used for rolling your own cigarette, cleaning eyeglass lenses, making notes and the like which are normally difficult to carry without becoming folded, crumpled or otherwise unusable. The dispenser includes a tubular housing receiving a roll of paper including a paper web and core rotatably mounted on a tubular spindle with one end of the paper web extending out through a discharge slot. A resilient band extends through the tubular spindle and biases the roll of paper against the wall of the tubular housing to resist free rotation thereof for controlling the discharge of paper through the discharge slot. The tubular housing also includes an opening for receiving the finger of a person using the device to enable a desired quantity of paper to be discharged by moving the roll of paper away from the interior wall surface of the housing and rotating the roll slightly for circumferential feeding of the end of the paper a short distance out of the discharge slot, where the paper can then be pulled.

2020010, Mar 26, 2020

Sep 25, 2018

16/140611

- Armonk NY, US
Matteo Cocchini - Long Island City NY, US
Zachary T. Dreiss - Beacon NY, US
Nicholas G. Danyluk - Long Island City NY, US
Edward N. Cohen - Poughkeepsie NY, US

H05K 1/02
G06F 17/50

A system and method to automatically determine power plane shape in a printed circuit board (PCB) involve obtaining inputs. The inputs include a size and shape of the PCB, a set of sources, and a set of sinks associated with a power plane. The method also includes determining a center of charge (CoC) as a center of largest current density for the set of sources and the set of sinks, and creating a sub-shape corresponding with a path from each source of the set of sources and from each sink of the set of sinks to the CoC. The creating the sub-shape includes determining a width of a conductor in the path corresponding with each of the sub-shapes. The sub-shapes created for the set of sources and the set of sinks are combined as the power plane shape.