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Edward G Melenski, 5415 Greenmeadow Dr, Limerick, PA 19468

Edward Melenski Phones & Addresses

15 Greenmeadow Dr, Royersford, PA 19468    610-2873709    484-9387898   

Limerick, PA   

748 Harper Ave, Drexel Hill, PA 19026    610-6226222    610-6229976   

112 Hemlock Dr, Collegeville, PA 19426    610-8311361   

Woodlyn, PA   

Wayne, PA   

Upper Darby, PA   

Montgomery, PA   

Mentions for Edward G Melenski

Edward Melenski resumes & CV records

Resumes

Edward Melenski Photo 13

Senior Research Associate, Moulder Center For Drug Discovery

Location:
15 Greenmeadow Dr, Royersford, PA 19468
Industry:
Pharmaceuticals
Work:
Execupharm Jun 2016 - Jul 2016
Medical Writer
Temple University School of Pharmacy Jun 2016 - Jul 2016
Senior Research Associate, Moulder Center For Drug Discovery
Icon Plc Oct 2013 - Jan 2015
Drug Safety Associate and Medical Writing
Icon Plc Aug 1, 2010 - Sep 2013
Medical Writer
Pfizer Dec 1992 - Oct 2009
Medicinal Chemist
Education:
Penn State University 1988 - 1992
Bachelors, Bachelor of Science
Skills:
Pharmaceutical Industry, Drug Discovery, Hplc, Organic Synthesis, Drug Development, Life Sciences, Oncology, Biotechnology, Clinical Development, Clinical Trials
Edward Melenski Photo 14

Owner At Ace Cleaning

Location:
Greater Philadelphia Area
Industry:
Environmental Services

Publications & IP owners

Us Patents

Thio-Oxindole Derivatives

US Patent:
6521657, Feb 18, 2003
Filed:
Oct 30, 2001
Appl. No.:
10/022467
Inventors:
Andrew Fensome - Wayne PA
Puwen Zhang - Audubon PA
Marci C. Koko - Bethlehem PA
Lin Zhi - San Diego CA
Todd K. Jones - Solana Beach CA
Jay E. Wrobel - Lawrenceville NJ
Christopher M. Tegley - Thousand Oaks CA
James P. Edwards - San Diego CA
Edward G. Melenski - Woodlyn PA
Assignee:
Wyeth - Madison NJ
Ligand Pharmaceuticals, Inc. - San Diego CA
International Classification:
A61K 31404
US Classification:
514414, 514418, 514336, 548466, 548486
Abstract:
This invention relates to compounds which are agonists of the progesterone receptor which have the general structure: wherein: R , R , R , R , R and Q are as defined herein, or a pharmaceutically acceptable salt thereof, as well as methods of using these compounds to induce contraception or treat progesterone-related carcinomas and adenocarcinomas.

Thio-Oxindole Derivatives

US Patent:
6583145, Jun 24, 2003
Filed:
Sep 24, 2002
Appl. No.:
10/253380
Inventors:
Andrew Fensome - Wayne PA
Puwen Zhang - Audubon PA
Marci C. Koko - Bethlehem PA
Lin Zhi - San Diego CA
Todd K. Jones - Solana Beach CA
Jay E. Wrobel - Lawrenceville NJ
Christopher M. Tegley - Thousand Oaks CA
James P. Edwards - San Diego CA
Edward G. Melenski - Woodlyn PA
Assignee:
Wyeth - Madison NJ
Ligand Pharmaceuticals - San Diego CA
International Classification:
A61K 31404
US Classification:
514256, 548483, 514415, 544333
Abstract:
This invention relates to compounds which are agonists of the progesterone receptor which have the general structure: wherein: R , R , R , R , R and Q are as defined herein, or a pharmaceutically acceptable salt thereof, as well as methods of using these compounds to induce contraception or treat progesterone-related carcinomas and adenocarcinomas.

Thio-Oxindole Derivatives

US Patent:
6841568, Jan 11, 2005
Filed:
Apr 22, 2003
Appl. No.:
10/420276
Inventors:
Andrew Fensome - Wayne PA, US
Puwen Zhang - Audubon PA, US
Marci C. Koko - Bethlehem PA, US
Jay E. Wrobel - Lawrenceville NJ, US
Edward G. Melenski - Woodlyn PA, US
Lin Zhi - San Diego CA, US
Todd K. Jones - Solana Beach CA, US
Christopher M. Tegley - Thousand Oaks CA, US
James P. Edwards - San Diego CA, US
Assignee:
Wyeth - Madison NJ
Ligand Pharmaceuticals, Inc. - San Diego CA
International Classification:
A61K 31405
C07D20904
US Classification:
514415, 548491
Abstract:
This invention relates to compounds which are agonists of the progesterone receptor which have the general structure: wherein:R, R, R, R, Rand Qare as defined herein, or a pharmaceutically acceptable salt thereof, as well as methods of using these compounds to induce contraception or treat progesterone-related carcinomas and adenocarcinomas.

Thio-Oxindole Derivatives

US Patent:
6946454, Sep 20, 2005
Filed:
Apr 5, 2002
Appl. No.:
10/117156
Inventors:
Andrew Fensome - Wayne PA, US
Puwen Zhang - Audubon PA, US
Marci C. Koko - Bethlehem PA, US
Lin Zhi - San Diego CA, US
Todd K. Jones - Solana Beach CA, US
Jay E. Wrobel - Lawrenceville NJ, US
Christopher M. Tegley - Thousand Oaks CA, US
James P. Edwards - San Diego CA, US
Edward G. Melenski - Woodlyn PA, US
Assignee:
Wyeth - Madison NJ
Ligand Pharmaceuticals, Inc. - San Diego CA
International Classification:
A61K031/56
A61K031/44
A61K031/40
US Classification:
514171, 514336, 514414, 514418
Abstract:
This invention relates to methods of co-administering compounds of formula 1 which are agonists of the progesterone receptor which have the general structure: wherein:.

Thio-Oxindole Derivatives

US Patent:
7091234, Aug 15, 2006
Filed:
Oct 20, 2004
Appl. No.:
10/969531
Inventors:
Andrew Fensome - Wayne PA, US
Puwen Zhang - Audubon PA, US
Marci C. Koko - Bethlehem PA, US
Lin Zhi - San Diego CA, US
Todd K. Jones - Solana Beach CA, US
Jay E. Wrobel - Lawrenceville NJ, US
Christopher M. Tegley - Thousand Oaks CA, US
James P. Edwards - San Diego CA, US
Edward G. Melenski - Woodlyn PA, US
Assignee:
Wyeth - Madison NJ
International Classification:
A61K 31/405
C07D 209/04
US Classification:
514415, 548469
Abstract:
This invention relates to compounds which are agonists of the progesterone receptor which have the general structure:.

Cyanopyrrole-Sulfonamide Progesterone Receptor Modulators And Uses Thereof

US Patent:
7291643, Nov 6, 2007
Filed:
Jul 27, 2006
Appl. No.:
11/494226
Inventors:
Casey Cameron McComas - Phoenixville PA, US
Andrew Fensome - Wayne PA, US
Edward George Melenski - Collegeville PA, US
Assignee:
Wyeth - Madison NJ
International Classification:
A61K 31/40
C07D 207/34
US Classification:
514427, 548561
Abstract:
Progesterone receptor modulators of formula I, or a pharmaceutically acceptable salt thereof,.

Cyanopyrrole-Phenyl Amide Progesterone Receptor Modulators And Uses Thereof

US Patent:
7297713, Nov 20, 2007
Filed:
Jul 27, 2006
Appl. No.:
11/494069
Inventors:
Casey Cameron McComas - Phoenixville PA, US
Andrew Fensome - Wayne PA, US
Edward George Melenski - Collegeville PA, US
Assignee:
Wyeth - Madison NJ
International Classification:
A61K 31/40
C07D 207/34
US Classification:
514427, 548561
Abstract:
Progesterone receptor modulators of formula I, or a pharmaceutically acceptable salt thereof,.

Progesterone Receptor Modulators Comprising Pyrrole-Oxindole Derivatives And Uses Thereof

US Patent:
7317037, Jan 8, 2008
Filed:
Jul 6, 2005
Appl. No.:
11/175824
Inventors:
Andrew Fensome - Wayne PA, US
Casey Cameron McComas - Phoenixville PA, US
Edward George Melenski - Collegeville PA, US
Michael Anthony Marella - Limerick PA, US
Jay Edward Wrobel - Lawrenceville NJ, US
Gary Sondermann Grubb - Newtown Square PA, US
Assignee:
Wyeth - Madison NJ
International Classification:
C07D 209/30
A61K 31/404
US Classification:
514414, 548411, 548466, 206569, 206570
Abstract:
Pyrrole-oxindole derivatives useful as progesterone receptor antagonists, and methods for preparing the same, are provided. Pharmaceutical compositions containing these derivatives are described, as is the use thereof in contraception and hormone-related conditions.

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