Eli R Cohen DeceasedBannockburn, IL

6537819, Mar 25, 2003

Apr 30, 2001

09/845222

Eli Cohen - Skokie IL
Peter R. Delmenico - Evanston IL
Gabriel Raviv - Glenview IL
William R. George - Santa Cruz CA
John A. Lake - Evanston IL

Haemoscope Corporation - Niles IL

G01N 3386

436 69, 600368, 600369, 600371, 73 6441, 73 6442, 422 73

A method and apparatus are provided for measuring hemostasis. The apparatus includes a torque sensing column having a torque sensing element and a drive ring disposed around a body of the column and in registration with the column so as to allow rotation of the drive ring around a longitudinal axis of the column. The apparatus further includes a first guide shaft rigidly secured to the drive ring, the guide shaft extending parallel to the longitudinal axis of the column and a cup holder movably attached to the guide shaft, allowing the cup holder to move parallel to the longitudinal axis of the column. The apparatus also includes a sample cup adapted to engage the cup holder on a outer surface and the torque sensing element of the torque sensing column on an inner surface.

6613573, Sep 2, 2003

Jun 9, 2000

09/591371

Eli Cohen - Skokie IL

Haemoscope Corporation - Skokie IL

G01N 3386

436 69, 422 73, 600368, 600369, 73 6441

A blood coagulation analyzer, such as the Thrombelastograph (TEGÂ) blood coagulation analyzer is utilized to measure continuously in real time, the clotting process from the initial fibrin formation, through platelet-fibrin interaction and lysis to generate blood coagulation parameters. The measured blood coagulation parameters permit confirmation of the attainment of therapeutic level of GPIIb/IIIa receptor blockade; individualized dosing assessment to evaluate attainment of adequate GPIIb/IIIa receptor blockade; individualized dosing assessment required to reach adequate GPIIb/IIIa receptor blockade; illustration of the rate of diminishment of platelet inhibition or inhibition recovery after treatment with platelet-inhibition drugs; evaluation of the interaction effect of a combination of thrombolytic or any other agents or conditions effecting hemostasis and platelet-inhibiting agents on patient hemostasis.

6787363, Sep 7, 2004

Oct 1, 2002

10/261331

Eli Cohen - Skokie IL
Irene A. Navickas - Northbrook IL

Haemoscope Corporation - Niles IL

G01N 3386

436 69, 422 73, 73 6441, 600369, 705 2, 709217

A procedure for hemostasis and blood management, particularly for cardiovascular procedures, provides: sampling instructions, i. e. , when to draw blood samples and how to pre-treat the blood samples, a decision tree to assist the interpretation of hemostasis analysis results allowing for the identification of various coagulopathies, and treatment suggestions related to the hemostasis analysis results. The analysis, interpretation and identification may be conducted by a suitably programmed computer.

6797519, Sep 28, 2004

Oct 10, 2001

09/974044

Eli Cohen - Skokie IL
Irene A. Navickas - Northbrook IL
Benjamin M. Cohen - Skokie IL
Barry N. Robinson - Chicago IL

Haemoscope Corporation - Niles IL

G01N 3386

436 69, 422 73, 600369, 705 2, 709217

A system and method for diagnosing hemostasis utilizing a communication network. A blood hemostasis analyzer tests a blood sample and provides a parameter indicative of hemostasis. The blood hemostasis analyzer is communicatively coupled via the communication network to an analysis tool. The analysis tool includes an algorithm operable on the parameter to provide a result. The diagnostic result may indicate normal hemostasis, a coagulopathy or other condition, and may provide a recommended course of treatment.

6890299, May 10, 2005

Apr 8, 2003

10/409479

Eli Cohen - Skokie IL, US
Irene Navickas - Northbrook IL, US

Haemoscope Corporation - Niles IL

A61B005/00
G01N033/86

600369, 436 69

A method and apparatus for monitoring hemostasis in a connection with a recipient of an artificial surface device provide a multi-phase monitoring protocol. In a first, pre- and intra-operative phase, hemostasis of the recipient is monitored relative to preventing clot formation to achieve artificial surface patency. In a second, post operative phase hemostasis of the recipient is monitored relative to bringing about clot formation to achieve vascular recovery. In a third, stabilizing intensive care phase hemostasis of the recipient is monitored relative to balancing hemostasis toward an anti-coagulation bias. In a fourth, maintenance phase hemostasis is monitored relative to maintaining balanced hemostasis.

7179652, Feb 20, 2007

Mar 7, 2003

10/384345

Eli Cohen - Skokie IL, US
Roslyn Cohen - Chicago IL, US
Roger Carroll - Knoxville TN, US

Haemoscope Corporation - Niles IL

G01N 33/86

436 69, 422 73, 435 13, 600368, 600369, 73 6441

A hemostasis analyzer, such as the Thrombelastograph (TEG) hemostasis analyzer is utilized to measure continuously in real time, the hemostasis process from the initial fibrin formation, through platelet-fibrin interaction and lysis to generate blood hemostasis parameters. The measured blood hemostasis parameters permit evaluation of platelet inhibition therapy.

7182913, Feb 27, 2007

Jul 31, 2003

10/631519

Eli Cohen - Skokie IL, US
Peter R. Delmenico - Evanston IL, US
Gabriel Ravin - Glenview IL, US
William R. George - Santa Cruz CA, US
John A. Lake - Evanston IL, US

Haemoscope Corporation - Niles IL

G01N 33/86

422 73, 436 69, 600368, 600369, 600371, 73 6441, 73 6442

A sample retention apparatus for use in a device for measuring hemostasis. The device for measuring hemostasis may include a sample articulation apparatus including a guide shaft coupled for articulating motion to a drive motor, a sample carrier secured to and axially moveable along the guide shaft between a sample ready position, a sample testing position and a sample ejection position. The sample carrier therefore articulates in unison with the articulating motion of the guide shaft. A measuring apparatus may include a sensing column. The sample retention apparatus may include a sample cup defining a volume within which a sample may be disposed. The sample cup may be adapted to be operably positioned within an aperture formed within the sample carrier. The sample testing apparatus may also include a sample pin that is engageable with the sensing column. The sample pin may include a tip portion for extending into the sample cup.

7524670, Apr 28, 2009

Aug 5, 2003

10/634553

Eli Cohen - Skokie IL, US
Roslyn Cohen - Chicago IL, US
Roger C. Carroll - Knoxville TN, US

Haemoscope Corporation - Niles IL

C12M 1/34

4352871

A hemostasis analyzer, such as the Thrombelastograph (TEG) hemostasis analyzer is utilized to measure continuously in real time, the hemostasis process from the initial fibrin formation, through platelet-fibrin interaction and lysis to generate blood hemostasis parameters. The measured blood hemostasis parameters permit determination of heparin-induced thrombocytopenia II complex (HiT II).