Elmer J Reist, 94581 Berkeley Ave, Menlo Park, CA 94025
Elmer Reist Phones & Addresses
581 Berkeley Ave, Menlo Park, CA 94025 650-3241445 650-9060595
Sunnyvale, CA
Palo Alto, CA
581 Berkeley Ave, Menlo Park, CA 94025
Work
Position:
Retired
Education
Degree:
Graduate or professional degree
Mentions for Elmer J Reist
Publications & IP owners
Us Patents
Method For Treating Herpes Viral Infections Using Benzothiophene Analogs.
US Patent:
5578615, Nov 26, 1996
Filed:
Apr 21, 1995
Appl. No.:
8/426212
Inventors:
Elmer J. Reist - Menlo Park CA
Assignee:
SRI International - Menlo Park CA
International Classification:
A61K 3144
US Classification:
514337
Abstract:
Benzothiophene analogs useful to treat herpes viral infections, particularly cytomegalovirus, are provided. These antiviral agents have the structural formula (I) ##STR1## wherein R and R. sup. 1 are as defined herein, and may be in free base or acid addition salt form. Pharmaceutical compositions are provided containing the antiviral agents, as are methods of treating herpes-infected individuals.
Benzothiophene Analogs As Antiviral Agents
US Patent:
5747511, May 5, 1998
Filed:
Apr 21, 1995
Appl. No.:
8/426262
Inventors:
Elmer J. Reist - Menlo Park CA
Assignee:
SRI International - Menlo Park CA
International Classification:
C07D40906
A61K 3144
A61K 3144
US Classification:
514337
Abstract:
Benzothiophene analogs useful to treat herpes viral infections, particularly cytomegalovirus, are provided. These antiviral agents have the structural formula (I) ##STR1## wherein R and R. sup. 1 are as defined herein, and may be in free base or acid addition salt form. Pharmaceutical compositions are provided containing the antiviral agents, as are methods of treating herpes-infected individuals.
Acyclic Purine Phosphonate Nucleotide Analogs As Antiviral Agents, And Related Synthetic Methods
US Patent:
5532225, Jul 2, 1996
Filed:
Jul 31, 1992
Appl. No.:
7/922937
Inventors:
Elmer J. Reist - Menlo Park CA
Beatrice Ruhland-Fritsch - Mountain View CA
Pricilla A. Sturm - Mountain View CA
Beatrice Ruhland-Fritsch - Mountain View CA
Pricilla A. Sturm - Mountain View CA
Assignee:
SRI International - Menlo Park CA
International Classification:
A61K 31675
C07F 96512
C07F 96512
US Classification:
514 81
Abstract:
Acyclic purine phosphonate nucleotide analogs useful to treat herpes viral infections are provided in enantiomerically pure form. These antiviral agents have the structural formula (Ia) or (Ib) ##STR1## and may be in acid, salt or ester form. Such compounds may also be dehydrated to provide antiviral agents in cyclic form. Pharmaceutical compositions are provided containing the antiviral agents, as is a chiral synthesis which may be used to prepare the agents in enantiomerically pure form or as a racemic mixture.
Benzothiophen Analogs As Antiviral Agents
US Patent:
5424315, Jun 13, 1995
Filed:
Aug 2, 1993
Appl. No.:
8/101371
Inventors:
Elmer J. Reist - Menlo Park CA
Assignee:
SRI International - Menlo Park CA
International Classification:
A61K 31435
C07D49506
C07D49506
US Classification:
514285
Abstract:
Benzothiophene analogs useful to treat herpes viral infections, particularly cytomegalovirus, are provided. These antiviral agents have the structural formula (I) ##STR1## wherein R and R. sup. 1 are as defined herein, and may be in free base or acid addition salt form. Pharmaceutical compositions are provided containing the antiviral agents, as are methods of treating herpes-infected individuals.
Acyclic Purine Phosphonate Nucleotide Analogs
US Patent:
5047533, Sep 10, 1991
Filed:
Jan 22, 1990
Appl. No.:
7/469791
Inventors:
Elmer J. Reist - Menlo Park CA
Priscilla A. Sturm - Mountain View CA
Priscilla A. Sturm - Mountain View CA
Assignee:
SRI International - Menlo Park CA
International Classification:
A61K 31675
C07F 96561
C07F 96561
US Classification:
544244
Abstract:
Certain open chain purine nucleoside phosphonate derivatives have antiviral activity against the Herpes group of viruses, and also show effective antiviral activity against retroviruses, including human immunodeficiency virus (HIV). These compounds have the formula ##STR1## wherein B represents a substituted or unsubstituted purine base, especially adenine or guanine and their halogenated derivatives. R1 is selected from H, methyl, hydroxymethyl, halomethyl, azidomethyl, and cyano; R2 is selected from H, methyl, hydroxymethyl, halomethyl, azidomethyl, cyano, and OH; also when R2 is OH the carbon to which it is attached may be oxidized so that the H there shown and R2 together may be =0; and n is an integer of 0-5. The compounds of the invention further include the pharmaceutically acceptable mono and dibasic salts and the mono- and diesters of the phosphonate moiety and the acid addition salts of the murine-substituted purines. In addition, when R1 or R2 is --CH. sub.
Enantiomerically Pure 2-Aminopurine Phosphonate Nucleotide Analogs As Antiviral Agents
US Patent:
5877166, Mar 2, 1999
Filed:
Apr 28, 1997
Appl. No.:
8/847881
Inventors:
Elmer J. Reist - Menlo Park CA
Wallace W. Bradford - Redwood City CA
Nurulain T. Zaveri - San Jose CA
Wallace W. Bradford - Redwood City CA
Nurulain T. Zaveri - San Jose CA
Assignee:
SRI International - Menlo Park CA
International Classification:
A61K 31675
C07F 96561
C07F 96561
US Classification:
514 81
Abstract:
Cyclic and acyclic 2-aminopurine phosphonate nucleotide analogs useful to treat herpes viral infections are provided in enantiomerically pure form. Pharmaceutical compositions and methods for treating herpes viral infections are provided as well, as is a chiral synthesis for preparing the novel compounds in enantiomerically pure form.
NOTICE: You may not use BackgroundCheck or the information it provides to make decisions about employment, credit, housing or any other purpose that would require Fair Credit Reporting Act (FCRA) compliance. BackgroundCheck is not a Consumer Reporting Agency (CRA) as defined by the FCRA and does not provide consumer reports.