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Eric L Wickstrom, 78787 24Th St, Philadelphia, PA 19130

Known as:
Eric W Wickstrom
Related to:
Jonell Smith 80 Luis J Wickstrom

Eric Wickstrom Phones & Addresses

787 24Th St, Philadelphia, PA 19130    215-7659362   

Tampa, FL   

Richardson, TX   

787 N 24Th St, Philadelphia, PA 19130    215-9713742   

Work

Position: Food Preparation and Serving Related Occupations

Education

Degree: Bachelor's degree or higher

Emails

c***[email protected]
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Eric Wickstrom resumes & CV records

Resumes

Eric Wickstrom Photo 29

Professor Of Biochemistry And Molecular Biology

Location:
Chicago, IL
Industry:
Biotechnology
Work:
Thomas Jefferson University Hospitals
Professor of Biochemistry and Molecular Biology University of South Florida Jun 1982 - Jun 1992
Assistant, Associate, and Full Professor Southernbiotech Jul 1981 - May 1982
Senior Research Scientist University of Denver Sep 1974 - Jun 1981
Assistant Professor of Chemistry University of Colorado Jan 1973 - Aug 1974
Research Associate
Education:
University of California, Berkeley 1968 - 1972
Doctorates, Doctor of Philosophy, Philosophy, Chemistry Caltech 1964 - 1968
Bachelors, Biology, Chemistry Evanston Township High School
Skills:
Molecular Biology, Life Sciences, Biotechnology, Research, Cell Biology, Microsoft Office, Management, Dna, Mentoring, Science, Microsoft Excel, C
Eric Wickstrom Photo 30

Plumber At The Pampering Plumber

Location:
10720 State Rd, Trinity, FL
Industry:
Building Materials
Work:
The Pampering Plumber
Plumber at the Pampering Plumber Duo Plumbing 2009 - 2011
Plumber Kci Wireless 2005 - 2008
Field Construction Superintendent Safeway Roofing Jan 1993 - Jan 2005
Roofing Superintendent Duo Plumbing Duo Plumbing & Heating Jan 1985 - Jul 1993
Plumber
Skills:
Roofers, Software Installation, Auditing, Payroll, Heavy Equipment, Pressure
Eric Wickstrom Photo 31

Eric Wickstrom

Eric Wickstrom Photo 32

Eric Wickstrom

Eric Wickstrom Photo 33

Professor At Thomas Jefferson University

Position:
Professor at Thomas Jefferson University
Location:
Greater Philadelphia Area
Industry:
Higher Education
Work:
Thomas Jefferson University
Professor
Education:
California Institute of Technology 1964 - 1968

Publications & IP owners

Us Patents

Antigenomic Oligodeoxynucleotides For Treatment Of Infection By Negative-Stranded Nonsegmented Rna Viruses

US Patent:
6355621, Mar 12, 2002
Filed:
Jun 26, 1998
Appl. No.:
09/105836
Inventors:
Zhen Fang Fu - Cherry Hill NJ
Eric Wickstrom - Philadelphia PA
Bernhard Dietzschold - Newtown Square PA
Hilary Koprowski - Wynnewood PA
Assignee:
Thomas Jefferson University - Philadelphia PA
International Classification:
C07H 2104
US Classification:
514 44, 435 6, 435455, 536 231, 536 241, 536 245
Abstract:
Oligodeoxynucleotides complementary to genomic RNA of a negative-stranded nonsegmented RNA virus are provided. Methods of inhibiting infection of cells by a negative-stranded nonsegmented RNA virus and treating animals infected with a negative-stranded nonsegmented RNA virus using these oligodeoxynucleotides are also provided.

Oligonucleotide Inhibitors Of Cancer Cell Proliferation

US Patent:
2002016, Nov 7, 2002
Filed:
May 7, 2002
Appl. No.:
10/141263
Inventors:
Eric Wickstrom - Philadelphia PA, US
International Classification:
A61K048/00
C07H021/04
US Classification:
514/044000, 536/023200
Abstract:
The K-RAS oncogene is a member of the highly conserved RAS gene family, whose protein products are believed to play a significant role in signal transduction and the regulation of cellular proliferation. Mutation-activated K-RAS is found in 30-50% of both advanced and early stage ovarian cancers. The present invention relates to a method for modulating mutation-activated K-RAS expression in ovarian, colon, lung, thyroid, prostate, skin, and hematologic cancer cells by administering an effective amount of an oligonucleotide targeted against a portion of mRNA for human K-RAS. Oligonucleotides are provided that are specifically hybridizable with mRNA encoding mutation-activated human K-RAS. Such oligonucleotides can be used for therapeutics and diagnostics as well as for research purposes. The present invention further encompasses pharmaceutical compositions comprising the antisense oligonucleotides of the invention.

Compounds And Methods For Diagnostic Imaging And Therapy

US Patent:
2005008, Apr 21, 2005
Filed:
Oct 16, 2003
Appl. No.:
10/688821
Inventors:
Eric Wickstrom - Philadelphia PA, US
Mathew Thakur - Cherry Hill NJ, US
Assignee:
Thomas Jefferson University - Philadelphia PA
International Classification:
A61K048/00
US Classification:
514012000, 514044000, 530324000, 530322000
Abstract:
Compounds comprising a diagnostic or therapeutic moiety can be retained inside a cell by conjugating the moiety to at least one PNA that is targeted to the transcripts from a gene of interest. The diagnostic or therapeutic moiety is also conjugated to at least one targeting moiety specific for an extracellular receptor or other cell surface molecule. The targeting moiety binds to the surface of a cell, and the entire compound is then internalized. Once inside the cell, the PNA portion of the diagnostic or therapeutic compound binds to RNA transcripts in a sequence specific manner. Binding of the PNA to its target RNA transcript retains the compound within the cell. The PNA can be designed to bind to a predetermined nucleic acid sequence from an RNA transcript, for example a mutated or overexpressed sequence that is characteristic of a pathological state.

Implants With Attached Silylated Therapeutic Agents

US Patent:
2006028, Dec 21, 2006
Filed:
Sep 14, 2004
Appl. No.:
10/572134
Inventors:
Eric Wickstrom - Philadelphia PA, US
Noreen Hickok - Philadelphia PA, US
Javad Parvizi - Philadelphia PA, US
International Classification:
A61F 2/28
A61K 38/14
A61K 31/7034
A61K 31/496
A61K 31/65
A61K 48/00
US Classification:
424423000, 623023760, 514008000, 514035000, 514152000, 514252130, 514044000
Abstract:
The present invention is directed to implants that include therapeutic molecules bonded to their surfaces. The therapeutic molecules interact with cells that are adjacent, near, or adhering to the implant. The covalently-bonded therapeutic molecules may be released from the implant surface by changes in pH or enzymes characteristic of cells adjacent to the implant. Preferably the covalently-bonded agents include an antibiotics that are released from the implant surface by bacteria and in this way ensures that the antibiotic is released at sites on the implant that would serve as centers for both bacterial colonization and biofilm formation.

Antisense Compounds And Methods For Diagnostic Imaging

US Patent:
2011012, May 26, 2011
Filed:
May 12, 2010
Appl. No.:
12/778376
Inventors:
Eric Wickstrom - Philadelphia PA, US
Mathew L. Thakur - Cherry Hill NJ, US
Assignee:
GENESEEN LLC - CHERRY HILL NJ
International Classification:
C12Q 1/68
C07K 9/00
US Classification:
435 6, 530322
Abstract:
Compounds comprising a diagnostic or therapeutic moiety can be retained inside a cell by conjugating the moiety to at least one PNA that is targeted to the transcripts from a gene of interest. The diagnostic or therapeutic moiety is also conjugated to at least one targeting moiety specific for an extracellular receptor or other cell surface molecule. The targeting moiety binds to the surface of a cell, and the entire compound is then internalized. Once inside the cell, the PNA portion of the diagnostic or therapeutic compound binds to RNA transcripts in a sequence specific manner. Binding of the PNA to its target RNA transcript retains the compound within the cell. The PNA can be designed to bind to a predetermined nucleic acid sequence from an RNA transcript, for example a mutated or overexpressed sequence that is characteristic of a pathological state.

Solid Phase Synthesis Of Oligonucleotides With Stereospecific Substituted Phosphonate Linkages By Pentavalent Grignard Coupling

US Patent:
5703223, Dec 30, 1997
Filed:
Sep 2, 1994
Appl. No.:
8/300259
Inventors:
Eric Wickstrom - Philadelphia PA
Christine Le Bec - Philadelphia PA
Assignee:
Thomas Jefferson University - Philadelphia PA
International Classification:
C07H 100
C07H 2104
US Classification:
536 2533
Abstract:
The present invention provides a method for producing an oligonucleotide having stereospecific substituted phosphonate linkages by use of a pentavalent Grignard coupling reaction on a solid phase support. The method can be used for automated synthesis of oligonucleotides having sequential equatorial or axial stereospecific substituted phosphonate linkages.

Composition And Method For Targeted Integration Into Cells

US Patent:
5958775, Sep 28, 1999
Filed:
Jul 23, 1998
Appl. No.:
9/121527
Inventors:
Eric Wickstrom - Philadelphia PA
Stephen Cleaver - Hatfield PA
Assignee:
Thomas Jefferson University - Philadelphia PA
International Classification:
C12N 1564
C12N 1581
C12N 1582
C12N 1585
US Classification:
435455
Abstract:
A vector containing a selected nucleic acid sequence interposed between the terminal ends of a Tn7 transposon and a method for site specific integration of genetic material into a chromosome using those vectors are provided.

Peptide Nucleic Acid Conjugates

US Patent:
6180767, Jan 30, 2001
Filed:
Jan 7, 1997
Appl. No.:
8/779072
Inventors:
Eric Wickstrom - Philadelphia PA
Soumitra Basu - New Haven CT
Assignee:
Thomas Jefferson University - Philadelphia PA
International Classification:
C07H 1900
C07H 2102
C07H 2100
C07H 2104
US Classification:
536 221
Abstract:
Peptide nucleic acid (PNA) oligomers are conjugated to a ligand which is capable of binding to a cell surface receptor. The ligand facilitates cellular uptake of the PNA oligomer. Where the ligand is a peptide, the conjugate may be produced as a unitary molecule by first synthesizing the peptide ligand by solid phase or solution peptide synthesis, followed by synthesis of the PNA oligomer as an extension of the peptide ligand. The PNA oligomer base sequence is selected to hybridize to a target polynucleotide sequence by either triplex (dsDNA) or duplex (ssDNA; RNA) formation.

Isbn (Books And Publications)

Prospects For Antisense Nucleic Acid Therapy Of Cancer And Aids

Author:
Eric Wickstrom
ISBN #:
0471568805

Clinical Trials Of Genetic Therapy With Antisense Dna And Dna Vectors

Author:
Eric Wickstrom
ISBN #:
0824700856

Possible Relatives

David M Wickstrom  Dean C Wickstrom  Daniel K Wickstrom  Darlene A Wickstrom  Donna J Wickstrom  Duane L Wickstrom  Frank C Wickstrom  Eric N Johnson  Eric Stamps  Eric P Stander 

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