Gary E Hewett, 7324766 2Nd St, Hayward, CA 94541

6645142, Nov 11, 2003

Dec 1, 2000

09/728743

James R. Braig - Piedmont CA
Gary E. Hewett - Castro Valley CA
Michael A. Munrow - Belmont CA
Julian M. Cortella - Alameda CA
Kamrava Azizi - San Ramon CA
Daniel S. Goldberger - Boulder CO

OptiScan Biomedical Corporation - Alameda CA

A61B 500

600300, 600316, 128903, 128904, 340501

A glucose monitoring instrument having network-based communication features which provide a link between patient and practitioner. The glucose monitoring instrument comprises circuitry for communicating data with one or more destination sites on the network which are configured to transmit and receive information to and from the instrument. Instrument measurements are transmitted over the link in addition to information and guidance, to provide increased accuracy, improved program compliance, and patient guidance from a supervisory authority or medical practitioner. In addition, a set of calibration features encourage calibration compliance.

2009011, May 7, 2009

Dec 4, 2007

11/950192

George Russell Warnick - Alameda CA, US
Gary Hewett - Hayward CA, US

Berkeley HeartLab, Inc. - Burlingame CA

C07K 1/18
C08J 5/20

521 27, 530359

Described are polymer monolith compositions for separating high density lipoprotein, as well as related methods of use.

5744096, Apr 28, 1998

Feb 21, 1997

8/803677

Ronald M. Jones - Mountain View CA
Eric G. Barr - Fremont CA
Gary E. Hewett - San Leandro CA

Cholestech Corporation - Hayward CA

G01N 3510

422 58

The invention relates to an immunoassay cassette useful for carrying out multistage immunoassays in an automated manner. In operation, the cassette assumes different operational positions in which solutions are transferred sequentially across an absorbent pathway containing assay reagents.

5171688, Dec 15, 1992

Aug 23, 1989

7/396326

Gary E. Hewett - Los Altos Hills CA
Steven T. Mielke - Fremont CA
Judith A. Blunt - Fremont CA

Cholestech Corporation - Hayward CA

C12M 136
C12Q 160
G01N 2100

435289

An assay device and method for determining the concentration of an analyte in a fluid sample. The device includes a porous-matrix reservoir which receives the sample to be assayed, and at least two reaction zones into which sample fluid is drawn from the reservoir. In an embodiment containing two reaction zones, a single-point standard curve which corrects for reduced-signal effects related to loss of reagent activity and linear inhibition effects, is used to determine analyte concentration. In an embodiment containing three reaction zones, a two-point standard curve which corrects for reduced-signal effects related loss of reagent activity and non-linear inhibition effects, is used to determine analyte concentration. Also disclosed is an apparatus which uses the device for automated or semi-automated analyte assay.

4851210, Jul 25, 1989

May 22, 1986

6/866350

Gary E. Hewett - Atherton CA

Genelabs Incorporated - Redwood City CA

G01N 3100

424 11

A membrane structure is disclosed having controlled capillarity useful in detecting cells in a solution by promoting effective contacting between cells and the membrane surface bearing affinity for selected cell sites. Also disclosed is a mtehod of using such membrane structures to detect particles in solution. One embodiment of the invention is an improved blood-typing device and method. The device may be attached to a blood bag, clamp, stick or the like, to provide a permanent visual record of blood type.

5156954, Oct 20, 1992

Mar 8, 1989

7/320414

Steven T. Mielke - Fremont CA
Gary E. Hewett - Milpitas CA

Cholestech Corporation - Hayward CA

C12Q 160
C12Q 134
C12Q 126
C12Q 128

435 18

An assay device and method for determining the concentration of an analyte. Analyte introduced by liquid absorption into the matrix is used to generate H2O2, via an analyte-specific oxidase, and the H. sub. 2 O. sub. 2 is utilized by peroxidase in the presence of peroxidase to convert a substrate reagent to a colored reaction product. A trapping compound in the matrix competes with the substrate reagent, in the presence of the peroxidase enzyme, to produce a silent reaction product, thus proportionately reducing the amount of signal reaction product generated by a given amount of analyte. Detection of a wider range of analyte concentrations is therefore possible.

5114350, May 19, 1992

Mar 8, 1989

7/320474

Gary E. Hewett - Milpitas CA

Cholestech Corporation - Hayward CA

C12M 134
C12M 140
G01N 2111

435288

Method and apparatus for use in determining the concentration of a selected analyte in a body-fluid sample. As the fluid sample is applied to a wettable, absorbent reaction pad, the extent of sample wetting of the pad is monitored by surface reflectance. This surface monitoring is used to control the volume of sample applied to the pad, to prevent overfilling the pad and to allow determination of the final sample volume applied. From the known sample volume and amount of analyte, the concentration of analyte in the sample can be accurately calculated in reaction components, trapping agents, matrix configuration, and analyte tested can be made.

5110724, May 5, 1992

Apr 2, 1990

7/503371

Gary E. Hewett - Atherton CA

Cholestech Corporation - Hayward CA

C12Q 160
G01N 2111

435 11

An assay device for assaying multiple analytes in a drop-size blood sample. The device includes a sample dispenser designed to distribute a small-volume blood sample to multiple transfer sites, by capillary flow of the blood sample through sieving and distributing matrices which separate blood cells from serum as the sample fluid migrates toward the transfer sites. A test plate in the device carries multiple absorbent test pads, each containing reagent components for use in detection of a selected analyte. The test plate is mounted on the dispenser for movement toward and away from a transfer position at which the exposed surface regions of the pads are in contact with associated sample-transfer sites, for simultaneous transfer of sample fluid from such sites to the pads in the support.