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George A Borg, 46Philadelphia, PA

George Borg Phones & Addresses

Philadelphia, PA   

Pittsburgh, PA   

Somerville, MA   

163 Charles St, Cambridge, MA 02141    617-9452950   

Riverside, CA   

Camarillo, CA   

Walnut Creek, CA   

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George A Borg

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George Borg

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George Borg Photo 32

Giorgio Borg Olivier

A monument in honour of George Borg Olivier was erected in Castille Square, Valletta in 1989, as part of the events commemorating the 25th anniversary of ...

Us Patents

Compounds And Methods Of Use

US Patent:
8178557, May 15, 2012
Filed:
Jun 9, 2008
Appl. No.:
12/157303
Inventors:
Michele Potashman - Cambridge MA, US
Steven Bellon - Wellesley MA, US
Shon Booker - Thousand Oaks CA, US
Yuan Cheng - Newbury Park CA, US
Joseph L. Kim - Wayland MA, US
Andrew Tasker - Simi Valley CA, US
Ning Xi - Thousand Oaks CA, US
Shimin Xu - San Diego CA, US
Jean-Christophe Harmange - Andover MA, US
George Borg - Somerville MA, US
Matthew Weiss - Boston MA, US
Brian L. Hodous - Cambridge MA, US
Russell Graceffa - Hampton NH, US
William H. Buckner - Kittery ME, US
Craig E. Masse - Cambridge MA, US
Deborah Choquette - Medford MA, US
Matthew W. Martin - Arlington MA, US
Julie Germain - Quebec, CA
Lucian V. DiPietro - Gloucester MA, US
Stuart C. Chaffee - Boston MA, US
Joseph J. Nunes - Andover MA, US
John L. Buchanan - Newton MA, US
David C. McGowan - Brussels, BE
Douglas A. Whittington - Waltham MA, US
Gregory J. Habgood - Merrimac MA, US
Vinod F. Patel - Acton MA, US
Daniel La - Brookline MA, US
Assignee:
Amgen Inc. - Thousand Oaks CA
International Classification:
A61K 31/04
US Classification:
514312
Abstract:
Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Compounds And Methods Of Use

US Patent:
2006024, Oct 26, 2006
Filed:
Jan 24, 2005
Appl. No.:
11/042634
Inventors:
Michele Potashman - Cambridge MA, US
Steven Bellon - Wellesley MA, US
Shon Booker - Thousand Oaks CA, US
Yuan Cheng - Newbury Park CA, US
Joseph Kim - Wayland MA, US
Andrew Tasker - Simi Valley CA, US
Ning Xi - Thousand Oaks CA, US
Shimin Xu - Santa Barbara CA, US
Jean-Christophe Harmange - Andover MA, US
George Borg - Cambridge MA, US
Matthew Weiss - Boston MA, US
Brian Hodous - Cambridge MA, US
Russell Graceffa - Hampton NH, US
William Buckner - Arlington MA, US
Craig Masse - Cambridge MA, US
Deborah Choquette - Medford MA, US
Matthew Martin - Cambridge MA, US
Julie Germain - Medford MA, US
Lucian DiPietro - Gloucester MA, US
Stuart Chaffee - Cambridge MA, US
Joseph Nunes - Andover MA, US
John Buchanan - Brookline MA, US
Gregory Habgood - Merrimac MA, US
David McGowan - Woluwe St. Pierre, BE
Douglas Whittington - Waltham MA, US
International Classification:
A61K 31/517
A61K 31/502
A61K 31/498
A61K 31/4709
C07D 43/02
US Classification:
514248000, 514249000, 514266200, 514314000, 544237000, 544284000, 544333000, 546167000
Abstract:
Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Acc Inhibitors And Uses Thereof

US Patent:
2016018, Jun 30, 2016
Filed:
May 8, 2014
Appl. No.:
14/890358
Inventors:
- Cambridge MA, US
Geraldine C. HARRIMAN - Charlestown RI, US
George BORG - Somerville MA, US
Craig E. MASSE - Cambridge MA, US
International Classification:
C07D 487/04
C07D 405/12
A01N 43/76
C07D 413/04
C07D 405/14
A01N 43/90
C07D 413/14
C07D 471/04
Abstract:
The present invention provides for compounds of formula I as acetyl-CoA carboxylase (ACC) inhibitors. The ACC inhibitors are useful for the prevention or treatment of metabolic syndrome, including obesity, dyslipidemia and hyperlipidemia in humans. The inhibitor compounds are also capable of inhibiting the ACC enzyme found in plants, parasites and bacteria.

Acc Inhibitors And Uses Thereof

US Patent:
2016018, Jun 30, 2016
Filed:
May 8, 2014
Appl. No.:
14/890344
Inventors:
- Cambridge MA, US
Geraldine C. Harriman - Charlestown RI, US
George Borg - Somerville MA, US
Craig E. Masse - Cambridge MA, US
International Classification:
C07D 513/04
A01N 43/90
C07D 495/04
Abstract:
The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.

Acc Inhibitors And Uses Thereof

US Patent:
2016010, Apr 21, 2016
Filed:
May 8, 2014
Appl. No.:
14/890308
Inventors:
- Cambridge MA, US
Geraldine C. Harriman - Charlestown RI, US
George Borg - Somerville MA, US
Craig E. Masse - Cambridge MA, US
International Classification:
C07D 513/04
A01N 43/90
C07D 487/04
C07D 495/04
Abstract:
The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.

Acc Inhibitors And Uses Thereof

US Patent:
2016010, Apr 21, 2016
Filed:
May 8, 2014
Appl. No.:
14/890320
Inventors:
- Cambridge MA, US
Geraldine C. Harriman - Charlestown RI, US
George Borg - Somerville MA, US
Craig E. Masse - Cambridge MA, US
International Classification:
C07D 513/04
A01N 43/90
C07D 471/04
C07D 487/04
C07D 498/04
Abstract:
The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same. Specifically, bicyclic heteroaryl derivatives containing a imidazole, thiazole or oxazole fused to a pyridinone, pyrimidinone or pyrimidindione are provided. These compounds have therapeutic utility toward treating an ACC enzyme mediated disorder such as obesity in a subject, upon administration in an effective amount to said subject.

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