George Edward Glover, 671981 Plymouth St, Philadelphia, PA 19138

2006023, Oct 19, 2006

Mar 17, 2004

10/549390

Harold Bramson - King of Prussia PA, US
George Glover - King of Prussia PA, US
Sanjay Khandekar - King of Prussia PA, US
Steven Ratcliffe - King of Prussia PA, US

C12Q 1/48

435015000, 435183000

The present invention provides methods for identifying compounds that inhibit kinases. In addition, methods for profiling protein kinases are also provided. In addition, methods for determining the mode of action of kinase inhibitors are also provided.

3936229, Feb 3, 1976

May 10, 1973

5/357401

George E. Glover - Philadelphia PA

Crane Co. - New York NY

B01F 720

416178

The liquid agitator is of the type used in stirring water containing small particles of suspended matter to cause the particles to come together and form agglomerations (e. g. , flocs) which will settle faster than the individual small particles. The agitator includes a paddle having pale elements and each of the pale elements has a predetermined shape, size and disposition so that said paddle produces a substantially uniform velocity gradient in the water being agitated when the paddle is rotated. The uniform velocity gradient developed will provide uniform agitation of the water to obtain uniform flocculation throughout the agitated volume even though the linear velocity of various portions of the paddle will be different depending on the radial distance of that portion from the vertical axis. Another embodiment utilizes a second paddle wherein the pale elements project between the pale elements of the first paddle, said second paddle can be stationary or counter rotated with reference to the first paddle.