Graham R Smith, 7150 Homers Wharf, New Bedford, MA 02740

7161964, Jan 9, 2007

Sep 11, 2002

10/241232

Anthony L. Lentine - Holmdel NJ, US
Graham H. Smith - Jersey City NJ, US
Ted K. Woodward - Holmdel NJ, US

Lucent Technologies Inc. - Murray Hill NJ

H04J 3/04

370535, 398 35

A reconfigurable ADD/DROP multiplexer/demultiplexer apparatus is implemented by connecting a multiplexer/demultiplexer apparatus to a serializer/deserializer (SERDES) apparatus having a loop-back capability. By selectively activating the loop-back functionality of the SERDES apparatus the combination can be made to function as a reconfigurable ADD/DROP multiplexer/demultiplexer apparatus.

7254335, Aug 7, 2007

Nov 8, 2001

10/008507

Brandon C. Collings - Middletown NJ, US
Anthony L. Lentine - Holmdel NJ, US
Martin C. Nuss - Fair Haven NJ, US
Graham Smith - Holmdel NJ, US
Ted K. Woodward - Fair Haven NJ, US

CIENA Corporation - Linthicum MD

H04J 14/02

398 82, 398 83

A module that includes both an “add-in”/“drop-out” pair of ports and a “drop-in”/“add-out” pair of ports comprises an arrangement of elements that combines an optical signal having a chosen wavelength with an optical signal applied at the “add-in” port, and outputs the combined signal at the “add-out port. ” Concurrently, the module extracts an optical signal with the same wavelength from an optical signal applied at the “drop-in” port signal, yielding an optical signal at the “drop-out” port that is missing that same wavelength. When the amount of information that needs to be sent from a first network node to a second, remote, node, is greater than that which a single wavelength can handle, a plurality of the above-described modules are interconnected within the first node by optically coupling the “add” ports in a “daisy chain” fashion and the “drop” ports in a “daisy chain” fashion, with each module operating at a different wavelength.

8604038, Dec 10, 2013

Aug 24, 2010

13/392282

Scott D. Edmondson - Clark NJ, US
Lehua Chang - Ramsey NJ, US
Nam Fung Kar - Brooklyn NY, US
Christopher R. Moyes - Westfield NJ, US
Cheng Zhu - Edison NJ, US
Neville J. Anthony - Northborough MA, US
Philip Jones - Houston TX, US
Graham F. Smith - Sudbury MA, US
Mark E. Scott - Andover MA, US
Christopher F. Thompson - Arlington MA, US
Joon Jung - Newton MA, US
Carolyn Cammarano - Worcester MA, US
Dawn Marie Hoffman - Boston MA, US

Merck Sharp & Dohme Corp. - Rahway NJ

A61K 31/50
A61K 31/525

51425205, 514383, 514343, 514256, 51425505, 514370, 514378, 514303, 514428, 5482676, 548199, 548247, 548570, 5462764, 546118, 544335, 544336, 544238

The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor.

2002003, Mar 28, 2002

May 21, 2001

09/862573

Anthony Lentine - Holmdel NJ, US
Graham Smith - Jersey City NJ, US
Ted Woodward - Holmdel NJ, US

H04J003/00
H04J003/04

370/521000, 370/535000, 370/540000

An apparatus and method for enabling the transport of a higher line rate time-multiplexed data signals (e.g., Ethernet at 10 Gb/s) at a lower line rate (e.g., SONET OC-192) and for regenerating the higher line rate time-multiplexed data signals at the receiving end. At a transmitter end, a data stream compression apparatus removes a predetermined portion of non-unique, invariant content of the higher line rate data stream thereby generating the lower line rate data stream which is transmitted over a communication link to the receiver end. At the receiver end, a data stream expansion apparatus adds back the missing predetermined portion of non-unique, invariant content to the lower line rate data stream thereby regenerating the higher line rate data stream. A data compression multiplexer apparatus is formed by combining a plurality of the data stream compression apparatuses with a data multiplexer. A data expansion demultiplexer apparatus is formed by combining a data demultiplexer with a plurality of the data stream expansion apparatuses.

4416635, Nov 22, 1983

Dec 24, 1981

6/334196

Graham M. Smith - Scotch Plains NJ

Merck & Co., Inc. - Rahway NJ

G09B 2326

434280

A molecular model of a relatively large molecule or a portion thereof is made up of a series of solid parallel and equidistant cross sections of rigid transparent plastic sheets representing space occupied by the atoms in the crystalline state. The adjacent cross sections are generated from x-ray crystal spectroscopic data providing crystal coordinates of the large molecules in computer readable form. Computer tapes of such data are used to print out numbered cross sections of the molecule showing coordinate plots of atoms intersecting such cross sections along a preselected coordinate axis. These cross sections are duplicated manually in clear rigid plastic sheets and assembled in order using appropriate spacer blocks to maintain accurate spacing of the adjacent cross section.

5921956, Jul 13, 1999

Sep 24, 1997

8/937359

Alexander Grinberg - Newton MA
Graham Smith - Plaistow NH

Smith & Nephew, Inc. - Andover MA

A61M 3700

604 95

A surgical instrument is steerable from the hub of the instrument to move a surgical tool to different offset positions. The instrument includes a shaft disposed along a longitudinal axis between a proximal region and a distal region at which the surgical tool is supported. A steering body is connected to the shaft proximally of the surgical tool and is configured to transmit proximally directed and distally directed forces applied by an actuator to a proximal end thereof to the shaft to bend the shaft in a flexible region of the shaft and offset the surgical tool from the longitudinal axis of the shaft.

2017027, Sep 28, 2017

Sep 25, 2015

15/515383

Michael D. ALTMAN - Boston MA, US
Brian M. ANDRESEN - Boston MA, US
Jason D. BRUBAKER - Cambridge MA, US
Matthew L. CHILDERS - Boston MA, US
Anthony DONOFRIO - Boston MA, US
Thierry FISCHMANN - Kenilworth NJ, US
Craig R. GIBEAU - Boston MA, US
Solomon D. KATTAR - Boston MA, US
Charles A. LESBURG - Boston MA, US
Jongwon LIM - Boston MA, US
John K.F. MACLEAN - Kilmarnock, Ayrshire Scotland, GB
Umar F. MANSOOR - Boston MA, US
Alan B. NORTHRUP - Boston MA, US
John SANDERS - West Point PA, US
Graham F. SMITH - Boston MA, US
Luis TORRES - Boston MA, US

MERCK SHARP & DOHME CORP. - RAHWAY NJ

C07D 498/04
A61K 31/517
C07D 403/04
C07D 239/94
C07D 401/04
A61K 31/5377
C07D 405/14
C07D 401/14
C07D 413/04
C07D 405/04
C07D 471/04
A61K 31/5383
C07D 491/048
C07D 417/04
C07D 409/04
A61K 45/06

The present invention relates to inhibitors of IRAK4 of Formula (I) and provides compositions comprising such inhibitors, as well as methods therewith for treating IRAK4-mediated or -associated conditions or diseases.

2017024, Aug 31, 2017

Sep 25, 2015

15/515396

MICHAEL D. ALTMAN - NEEDHAM MA, US
JASON D. BRUBAKER - CAMBRIDGE MA, US
MATTHEW L. CHILDERS - MEDFIELD MA, US
ANTHONY DONOFRIO - CAMBRIDGE MA, US
THIERRY FISCHMANN - SCOTCH PLAINS NJ, US
CRAIG R. GIBEAU - HOLLISTON MA, US
SOLOMON D. KATTAR - WAKEFIELD MA, US
CHARLES A. LESBURG - NEWTON MA, US
JONGWON LIM - LEXINGTON MA, US
JOHN K.F. MACLEAN - AYRSHIRE, GB
UMAR F. MANSOOR - HOPKINTON MA, US
ALAN B. NORTHRUP - READING MA, US
JOHN M. SANDERS - HATFIELD PA, US
GRAHAM F. SMITH - SUDBURY MA, US

MERCK SHARP & DOHME CORP. - RAHWAY NJ

C07D 491/107
C07D 239/94
A61K 31/5377
C07D 417/12
C07D 401/12
C07D 405/12
C07D 409/12
A61K 31/541
A61K 31/517
C07D 403/12

The present invention relates to inhibitors of IRAK4 of Formula I and provides compositions comprising such inhibitors, as well as methods therewith for treating IRAK4-mediated or -associated conditions or diseases.