Gregory Koll resumes & CV records
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Gregory Edwin Koll, 67New York, NY
Gregory Koll Phones & Addresses
New York, NY
Mahwah, NJ
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Publications & IP owners
Us Patents
Flavoring Of Drug-Containing Chewing Gums
US Patent:
8323683, Dec 4, 2012
Filed:
May 18, 2005
Appl. No.:
11/131561
Inventors:
Seema Mody - Montville NJ, US
Gregory Koll - Hillsborough NJ, US
Gregory Koll - Hillsborough NJ, US
Assignee:
McNeil-PPC, Inc. - Skillman NJ
International Classification:
A24B 15/16
A24B 15/00
A23G 4/00
A23G 4/08
A24B 15/00
A23G 4/00
A23G 4/08
US Classification:
424440, 424 48, 424439, 426 3, 426 4, 426 5, 426103, 426 6, 131270
Abstract:
A chewing gum comprising at least one active pharmaceutical ingredient (API) with a core onto which is applied at least one inner polymer film coating and thereafter onto which is applied at least one outer hard coating. A preferred API is nicotine. Flavoring agents may be incorporated in the core, in the at least one inner polymer film coating and/or in the at least one outer hard coating. The gums formed exhibit a long lasting effect of flavoring agent(s) and result in the domination of flavoring agents in the coating(s) over flavoring agent(s) in the core, thereby (a) avoiding problems of chemical or pharmaceutical incompatibility between an API in the core and flavoring agent(s) in the coating(s) and (b) achieving an increased control of the release of the API and of non-active excipients.
New Product And Use And Manufacture Thereof
US Patent:
2007026, Nov 22, 2007
Filed:
Jun 1, 2006
Appl. No.:
11/444787
Inventors:
Per Steen - Astorp, SE
Darek Dymitrowicz - Malmo, SE
Andreas Hugerth - Malmo, SE
Asa Waltermo - Odakra, SE
Magnus Palsson - Helsinborg, SE
Roland Olsson - Helsingborg, SE
Fredrik Nicklasson - Bjarred, SE
Anette Schluter - Rydeback, SE
Kristina Thyresson - Lund, SE
Seema K. Mody - Montville NJ, US
Bengt Bosson - Helsingborg, SE
Katarina Lindell - Eslov, SE
Gregory Koll - Hillsborough NJ, US
Darek Dymitrowicz - Malmo, SE
Andreas Hugerth - Malmo, SE
Asa Waltermo - Odakra, SE
Magnus Palsson - Helsinborg, SE
Roland Olsson - Helsingborg, SE
Fredrik Nicklasson - Bjarred, SE
Anette Schluter - Rydeback, SE
Kristina Thyresson - Lund, SE
Seema K. Mody - Montville NJ, US
Bengt Bosson - Helsingborg, SE
Katarina Lindell - Eslov, SE
Gregory Koll - Hillsborough NJ, US
International Classification:
A61K 31/4439
A61K 9/68
A61K 9/68
US Classification:
424 48, 424440, 514343
Abstract:
A pharmaceutical oral formulation for delivering nicotine in any form to a subject by transmucosal uptake in the oral cavity comprising nicotine in any form, wherein said oral formulation is buffered with at least trometamol. Also contemplated is a method for the oral delivery of nicotine in any form, a method for the reduction of the urge to smoke or use tobacco as well as methods for manufacturing the oral formulation, the use of the oral formulation for obtaining transmucosal uptake of nicotine in the oral cavity of a subject, and use of nicotine for the production of an oral formulation for the treatment of a disease selected from the group consisting of tobacco or nicotine dependence, Alzheimer's disease, Crohn's disease, Parkinson's disease, Tourette's syndrome, ulcerous colitis and post-smoking-cessation weight control.
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