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Heather Demille Hirsch, 42PO Box 358, Fairport, NY 14450

Heather Hirsch Phones & Addresses

Fairport, NY   

Pittsford, NY   

South Dennis, MA   

West Newton, MA   

Thornville, OH   

Columbus, OH   

Cleveland, OH   

Mentions for Heather Demille Hirsch

Career records & work history

Lawyers & Attorneys

Heather Hirsch Photo 1

Heather Hirsch - Lawyer

ISLN:
1000864292
Admitted:
2019
Heather Hirsch Photo 2

Heather Hirsch - Lawyer

Office:
Law Offices Tobin • Lucks LLP
Specialties:
Worker's Compensation
ISLN:
921521936
Admitted:
2009
University:
University of California at Los Angeles, B.A.
Law School:
University of La Verne College of Law, J.D., 2009

License Records

Heather Ann Hirsch

Licenses:
License #: 42349 - Expired
Category: Nursing Support
Issued Date: Feb 1, 2000
Effective Date: Mar 31, 2004
Expiration Date: Feb 1, 2003
Type: Medication Aide

Publications & IP owners

Us Patents

Use Of Metformin In Cancer Treatment And Prevention

US Patent:
2012022, Aug 30, 2012
Filed:
Aug 25, 2010
Appl. No.:
13/391890
Inventors:
Kevin Struhl - Weston MA, US
Heather Hirsch - Boston MA, US
Dimitrios Iliopoulos - Brighton MA, US
Assignee:
PRESIDENT AND FELLOWS OF HARVARD COLLEGE - Cambridge MA
International Classification:
A61K 31/155
A61P 35/00
US Classification:
514635
Abstract:
Disclosed herein is a method for treating a tumor in a subject in need thereof comprising administering an enhancing amount of metformin and a reduced amount of one or more chemotherapeutic agents. One example of an enhancing amount of metformin is about 250 mg/day. Also disclosed is a Untreated method for preventing cancer or delaying the recurrence of cancer in a subject comprising administering an effective amount of metformin to the subject. In one example of such a method, the amount of metformin is about 75 mg/day. Also disclosed is a composition comprising an enhancing amount of metformin, and a reduced amount of one or more chemotherapeutic agents and a pharmaceutically acceptable carrier. Kits comprising metformin and one or more chemotherapeutic agents are also disclosed.

Gene Signatures For Determining Icos Expression

US Patent:
2021034, Nov 4, 2021
Filed:
Feb 5, 2021
Appl. No.:
17/168544
Inventors:
- Cambridge MA, US
Igor Feldman - Jamaica Plain MA, US
Christopher Harvey - Boston MA, US
Sriram Sathyanarayanan - Lexington MA, US
Heather Hirsch - Brookline MA, US
Lauren Pepper MacKenzie - Cambridge MA, US
Amit Deshpande - Cambridge MA, US
Stephen Sazinsky - Melrose MA, US
Jennifer S. Michaelson - Brighton MA, US
Kutlu Goksu Elpek - Arlington MA, US
Assignee:
Jounce Therapeutics, Inc. - Cambridge MA
International Classification:
C07K 16/28
C12Q 1/6886
A61P 35/00
A61K 39/00
A61K 39/395
Abstract:
Gene expression signatures correlating to ICOS expression levels are provided. Methods of treatment comprising determining ICOS expression levels using gene signatures in patients and administering anti-ICOS antibodies are also provided.

Gene Signatures For Determining Icos Expression

US Patent:
2018037, Dec 27, 2018
Filed:
Oct 21, 2016
Appl. No.:
15/767172
Inventors:
- Cambridge MA, US
Igor Feldman - Jamaica Planin MA, US
Christopher Harvey - Boston MA, US
Sriram Sathyanarayanan - Lexington MA, US
Heather Hirsch - Brookline MA, US
Lauren Pepper MacKenzie - Cambridge MA, US
Amit Deshpande - Cambridge MA, US
Stephen Sazinsky - Melrose MA, US
Jennifer S. Michaelson - Brighton MA, US
Kutlu Gosku Elpek - Arlington MA, US
Assignee:
Jounce Therapeutics, Inc. - Cambridge MA
International Classification:
C07K 16/28
C12Q 1/6886
A61P 35/00
Abstract:
Gene expression signatures correlating to ICOS expression levels are provided. Methods of treatment comprising determining ICOS expression levels using gene signatures in patients and administering anti-ICOS antibodies are also provided.

Predictive Biomarker Useful For Cancer Therapy Mediated By A Cdk Inhibitor

US Patent:
2015005, Feb 19, 2015
Filed:
Mar 27, 2013
Appl. No.:
14/388385
Inventors:
- Rahway NJ, US
Heather A. Hirsch - Brookline MA, US
Leigh Scott Zawel - Weston MA, US
Stephen Eric Fawell - Framingham MA, US
Assignee:
Merck Sharp & Dohme Corp. - Rahway NJ
International Classification:
G01N 33/574
US Classification:
5142593, 506 9, 435 612
Abstract:
The present invention provides a predictive biomarker whose expression level is useful for identifying patients responsive to a therapeutically effective dose of a CDK inhibitor. In one embodiment of the invention, the predictive biomarker is the ratio of MCL-1 to BCL-xL (MCL-1:BCL-xL ratio) and the CDK inhibitor is SCH 927965 (Dinaciclib).

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