Hongmei M Zhang, 51Lexington, MA

2019031, Oct 10, 2019

Apr 5, 2019

16/376264

- Cambridge MA, US
Hongmei Zhang - Lexington MA, US

G01N 27/414
G01N 33/543
H01L 51/00
G01N 33/00

The present disclosure describes a solution to rapidly detect trace amounts of biomarkers present in a fluid sample. The solution can be, for example, used to diagnosis sepsis through the detection of nitric oxide. The solution includes one or more organic electrochemical transistors that are functionalized with a bio-recognition coating. The bio-recognition coating can bind or otherwise interact with the biomarkers to change the transconductance of the organic electrochemical transistors. The solution can detect the change in the transconductance of the organic electrochemical transistors and signal the presence of the biomarker.

2018009, Apr 5, 2018

May 11, 2017

15/592694

- Cambridge MA, US
Amy DuweI - Cambridge MA, US
Anthony Kopa - Cambridge MA, US
Seth Davis - Cambridge MA, US
Andrew P. Magyar - Cambridge MA, US
Brian Smith - Cambridge MA, US
Mitchell W. Meinhold - Cambridge MA, US
Sara Barron - Cambridge MA, US
Gregory Romano - Cambridge MA, US
Richard Morrison - Cambridge MA, US
Hongmei Zhang - Cambridge MA, US

H05K 3/34
H01B 13/016
H05K 1/11
H05K 3/32
H01R 43/02
H01R 9/05

A method for attaching a prefabricated miniature coaxial wire to a first electrical connection point, the prefabricated miniature coaxial wire having an electrically conductive core disposed within an electrical insulation layer disposed within an electrically conductive shield layer, includes attaching an exposed portion of the electrically conductive core at a distal end of the prefabricated miniature coaxial wire to the first electrical connection point, thereby establishing electrical conductivity between the electrically conductive core and the first electrical connection point, depositing a layer of electrically insulating material onto the exposed portion of the electrically conductive core such that the exposed portion of the electrically conductive core and the first electrical connection point is encased in the layer of electrically insulating material, and connecting the electrically conductive shield layer to a second electrical connection point using a connector formed from an electrically conductive material.