Inventors:
Nora Sarvetnick - San Diego CA, US
Howard Fox - San Diego CA, US
Assignee:
The Scripps Research Institute - La Jolla CA
International Classification:
C07K016/00
C12P021/08
US Classification:
5303879, 436547, 436548, 530350, 530380, 5303871, 5303881, 5303882, 5303891, 5303892, 530866
Abstract:
Methods for isolating pancreatic progenitor 1 genes are provided. The pancreatic progenitor 1 nucleic acid compositions find use in identifying homologous or related proteins and the DNA sequences encoding such proteins; in producing compositions that modulate the expression or function of the protein; and in studying associated physiological pathways. In addition, modulation of the gene activity in vivo is used for prophylactic and therapeutic purposes, such as identification of cell type based on expression, and the like.