Hua Gu resumes & CV records
Resumes
Hua Gu
Hua Gu7 Frost Creek Dr, Matinecock, NY 11560
Hua Gu Phones & Addresses
7 Frost Creek Dr, Locust Valley, NY 11560
Glen Cove, NY
Long Island City, NY
Mentions for Hua Gu
Publications & IP owners
Us Patents
Agents And Methods To Elicit Anti-Tumor Immune Response
US Patent:
2011028, Nov 24, 2011
Filed:
Sep 13, 2007
Appl. No.:
12/441335
Inventors:
Hua Gu - New York NY, US
Richard Hodes - Bethesda MD, US
Jeffrey J. Chiang - Herndon VA, US
Ihnkyung Jang - New York NY, US
Richard Hodes - Bethesda MD, US
Jeffrey J. Chiang - Herndon VA, US
Ihnkyung Jang - New York NY, US
Assignee:
The Government of the United States of America as represented by the Secretary of the Dept of the HH - Rockville MD
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK - New York NY
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK - New York NY
International Classification:
A61K 35/14
A61M 37/00
A61P 35/00
A61P 37/04
C12N 5/0783
G01N 33/566
A61M 37/00
A61P 35/00
A61P 37/04
C12N 5/0783
G01N 33/566
US Classification:
4242771, 435375, 435 71, 435 792, 604522
Abstract:
The invention provides an isolated, purified population of human cells comprising CD8+ T cells with reduced Cbl-b activity. The invention provides uses of such cells in methods for inducing or enhancing an anti-tumor immune response in a subject. These methods comprise: (a) providing a cell population, from a subject or from another source, which comprises CD8+ T cells, (b) reducing Cbl-b activity in the CD8+ T-cells, (c) administering the cells of step (b) to the subject. The invention provides methods for making CD8+ T cells that do not require stimulation through a co-receptor in order for the cell to become activated or proliferated in response to contact via its T cell receptor. Such methods are based upon reducing function of Cbl-b. The invention also provides methods for identifying agents which affect Cbl-b expression or activity.
Inhibitory Rnas That Regulate Hematopoietic Cells
US Patent:
2011017, Jul 21, 2011
Filed:
May 8, 2009
Appl. No.:
12/991656
Inventors:
Hua Gu - New York NY, US
Christoph Park - Stanford CA, US
Irving Weissman - Stanford CA, US
Christoph Park - Stanford CA, US
Irving Weissman - Stanford CA, US
International Classification:
A61K 31/7088
C12Q 1/68
C12N 5/071
C12N 5/0786
C12N 5/0787
A61P 35/00
A61P 35/02
C12Q 1/68
C12N 5/071
C12N 5/0786
C12N 5/0787
A61P 35/00
A61P 35/02
US Classification:
514 44 A, 435 614, 435375, 435 613
Abstract:
Provided are compositions and methods for preventing, treating, ameliorating or diagnosing conditions or diseases involving a myeloid cell proliferation disorder. Such compositions and methods target miRNA function myeloproliferative diseases. More particularly, such compositions and methods target miR-29a function in myeloid cell proliferation disorders. Also provided are methods for diagnosing risk or presence of a myeloid cell proliferation disorder in a subject.
Possible Relatives
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